Isocyanates
Cayman Chemical Perifosine Fatty Acids and Der
An alkylphospholipid that induces apoptotic cell death in a time- and dose-dependent manner in a variety of tumor cell lines but not in normal vascular endothelial cells; causes inhibition of PC-3 prostate carcinoma cell growth (GI50 = 5 µM at 24h) associated with rapidly decreased Akt activation; induces p21WAF1 expression in squamous carcinoma cells, leading to loss in cyclin-dependent kinase activity and cell cycle arrest
Cayman Chemical 11 12EpETE Fatty Acids and Der
An epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo; its effects of remain to be determined
Medchemexpress LLC XL-3158 | 3117797-77-7 | 99.6% | 690.61 | 100 MG
XL-3158 | 3117797-77-7 | 99.6% | 690.61 | 100 MG
Medchemexpress LLC 2-Amino-5-methylbenzoic acid | 2941-78-8 | 151.16 | 500 G
2-Amino-5-methylbenzoic Acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is an impurity of cetilistat.
- Biochemical reagent
- Biological material or organic compound
- Used for life science related research
- Off-white to light yellow solid appearance
- Purity of 99.8%
- Molecular weight of 151.16
- Store powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
Cayman Chemical 16 17EpDPA Fatty Acids and Der
A DHA metabolite derived via epoxidation of the 16,17-double bond; epoxygenase metabolites of DHA have been detected in a mouse model of inflammation
Medchemexpress LLC Hexamethylene bisace | 3073-59-4 | 99.6% | 200.28 g/mol | C10H20N2O2 | 200MG
Hexamethylene bisacetamide (HMBA) is a research reagent used to induce cell differentiation and to study apoptosis and related signaling pathways. It is supplied as a solid and as DMSO solutions for in vitro laboratory applications, and is offered in multiple pack sizes for different experimental scales.
- Induces cell differentiation in multiple cell lines.
- Used to study apoptosis and signaling pathways.
- Supplied as a solid and as DMSO solutions for flexible use.
- Available in multiple pack sizes to suit experimental scale.
- High purity (99.6%) suitable for analytical and research use.
Medchemexpress LLC FG-3019 10mg | 10mg
FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF) FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF)[1][2]
Medchemexpress LLC XL-3158 | 3117797-77-7 | 99.5% | 690.61 | 200 MG
XL-3158 is a selective and cross-species Cyclic GMP-AMP synthase (cGAS) inhibitor. It simultaneously occupies allosteric and orthosteric sites, stabilizing the activation loop in a closed, inactive conformation, thereby attenuating cGAS-DNA interactions. It efficiently penetrates cells by inhibiting aggregate formation, effectively reducing the local concentration of cGAS within cells. This compound can be used for the study of cGAS-dependent inflammatory diseases.
- Blocks cGAS intracellular condensation with DNA by inhibiting cGAS phase separation in L929 cells.
- Specifically inhibits downstream signaling activation of the cGAS-STING pathway in THP-1 Dual cells.
- Selectively inhibits the DNA-triggered cGAS-dependent interferon pathway in THP-1 Dual cells.
- Has CC50 values of 77.55 μM against THP-1 cells and 56.79 μM against RAW-ISG cells.
- Attenuates Cerulein-induced acute pancreatitis.
Medchemexpress LLC Benzoic acid, 2-amino-6-methyl- | 4389-50-8 | 99.4% | 151.16 | 10 G
2-Amino-6-methylbenzoic acid is a biochemical reagent suitable for life science-related research, where it can be utilized as a biological material or an organic compound. It is specifically mentioned that this compound reacts with cyanogen bromide to form 2-amino-5-methyl-benzo[d]oxazin-4-one. The product is intended for research use only.
- Biochemical reagent for life science research
- Can be used as a biological material
- Can be used as an organic compound
- High purity: 99.36%