Isocyanates
Sigma Aldrich Fine Chemicals Biosciences Cyclohexyl isocyanate 98% | 3173-53-3 | MFCD00003840 | 100G
Cyclohexyl isocyanate 98% | Purity: 98% | Mol Wt: 125.17 | 3173-53-3 | MFCD00003840 | 100G
eMolecules 4747-21-1 | N-ISOPROPYLMETHYLAMINE | AstaTech | MFCD00042859 | 73.139 | C4H11N | 97.000 | CNC(C)C | 5g | 721956263
N-ISOPROPYLMETHYLAMINE | AstaTech | 4747-21-1 | MFCD00042859 | 73.139 | C4H11N | 97.000 | CNC(C)C | 5g | 721956263
Medchemexpress LLC XL-3158 | 3117797-77-7 | 99.5% | 690.61 | 200 MG
XL-3158 is a selective and cross-species Cyclic GMP-AMP synthase (cGAS) inhibitor. It simultaneously occupies allosteric and orthosteric sites, stabilizing the activation loop in a closed, inactive conformation, thereby attenuating cGAS-DNA interactions. It efficiently penetrates cells by inhibiting aggregate formation, effectively reducing the local concentration of cGAS within cells. This compound can be used for the study of cGAS-dependent inflammatory diseases.
- Blocks cGAS intracellular condensation with DNA by inhibiting cGAS phase separation in L929 cells.
- Specifically inhibits downstream signaling activation of the cGAS-STING pathway in THP-1 Dual cells.
- Selectively inhibits the DNA-triggered cGAS-dependent interferon pathway in THP-1 Dual cells.
- Has CC50 values of 77.55 μM against THP-1 cells and 56.79 μM against RAW-ISG cells.
- Attenuates Cerulein-induced acute pancreatitis.
Cayman Chemical Lipoxin A5 Fatty Acids and Der
A 5-series LO derived from EPA; contracts pulmonary parenchymal strips from guinea pig with similar potency to that of LXA4 and LXB4, yet does not exert the vasodilatory effects on aortic smooth muscle exhibited by LXA4 and LXB4
Medchemexpress LLC XL-3158 | 3117797-77-7 | 99.6% | 690.61 | 100 MG
XL-3158 | 3117797-77-7 | 99.6% | 690.61 | 100 MG
eMolecules 1189-71-5 | Chlorosulfonyl isocyanate | Chem-Impex | MFCD00011608 | 141.530 | CClNO3S | 99.000 | ClS(=O)(=O)N=C=O | 250g | 603112020
Chlorosulfonyl isocyanate | Chem-Impex | 1189-71-5 | MFCD00011608 | 141.530 | CClNO3S | 99.000 | ClS(=O)(=O)N=C=O | 250g | 603112020
eMolecules 1189-71-5 | Chlorosulfonyl isocyanate | Chem-Impex | MFCD00011608 | 141.530 | CClNO3S | 99.000 | ClS(=O)(=O)N=C=O | 25g | 603112018
Chlorosulfonyl isocyanate | Chem-Impex | 1189-71-5 | MFCD00011608 | 141.530 | CClNO3S | 99.000 | ClS(=O)(=O)N=C=O | 25g | 603112018
Medchemexpress LLC FG-3019 10mg | 10mg
FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF) FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF)[1][2]
Cayman Chemical 19 20EpDPA Fatty Acids and Der
An epoxide metabolite of DHA; formed from DHA by various CYP isoforms; suppresses hCLS formation and liver fibrosis in wild-type mice in a model of NASH at 100 ng/animal, i.p., intraplantar administration induces acute mechanical hyperalgesia in mice