Isocyanates
Medchemexpress LLC Der p 23 protein, Dermatophagoides pteronyssinus | >95.0% | 100 UG
Der p 23 is a recombinant major allergen from the house dust mite Dermatophagoides pteronyssinus, expressed in HEK293 cells and supplied as a lyophilized C-terminal His-tagged protein. It is >95% pure by reducing SDS-PAGE, has an approximate molecular weight of 19 kDa, and endotoxin <1 EU/μg. The product is formulated in PBS (pH 7.4) and is recommended to be stored at -20°C; add carrier protein for long-term storage.
- Recombinant protein expressed in HEK293 cells.
- C-terminal His tag for purification and detection.
- High purity (>95%) suitable for immunological assays.
- Low endotoxin level (<1 EU/μg) for sensitive applications.
- Lyophilized formulation; PBS-based, recommended -20°C storage.
Cayman Chemical Perifosine Fatty Acids and Der
An alkylphospholipid that induces apoptotic cell death in a time- and dose-dependent manner in a variety of tumor cell lines but not in normal vascular endothelial cells; causes inhibition of PC-3 prostate carcinoma cell growth (GI50 = 5 µM at 24h) associated with rapidly decreased Akt activation; induces p21WAF1 expression in squamous carcinoma cells, leading to loss in cyclin-dependent kinase activity and cell cycle arrest
Cayman Chemical Perifosine Fatty Acids and Der
An alkylphospholipid that induces apoptotic cell death in a time- and dose-dependent manner in a variety of tumor cell lines but not in normal vascular endothelial cells; causes inhibition of PC-3 prostate carcinoma cell growth (GI50 = 5 µM at 24h) associated with rapidly decreased Akt activation; induces p21WAF1 expression in squamous carcinoma cells, leading to loss in cyclin-dependent kinase activity and cell cycle arrest
Cayman Chemical Perifosine Fatty Acids and Der
An alkylphospholipid that induces apoptotic cell death in a time- and dose-dependent manner in a variety of tumor cell lines but not in normal vascular endothelial cells; causes inhibition of PC-3 prostate carcinoma cell growth (GI50 = 5 µM at 24h) associated with rapidly decreased Akt activation; induces p21WAF1 expression in squamous carcinoma cells, leading to loss in cyclin-dependent kinase activity and cell cycle arrest
Cayman Chemical Perifosine Fatty Acids and Der
An alkylphospholipid that induces apoptotic cell death in a time- and dose-dependent manner in a variety of tumor cell lines but not in normal vascular endothelial cells; causes inhibition of PC-3 prostate carcinoma cell growth (GI50 = 5 µM at 24h) associated with rapidly decreased Akt activation; induces p21WAF1 expression in squamous carcinoma cells, leading to loss in cyclin-dependent kinase activity and cell cycle arrest
Medchemexpress LLC Der p 23 protein (Dermatophagoides pteronyssinus) | >95.0% | 50 UG
Recombinant Der p 23 protein derived from the house dust mite Dermatophagoides pteronyssinus. Supplied lyophilized in a 50 μg vial, this sequence-verified allergen is intended for research use in allergy and immunology studies where defined recombinant antigen is required.
- Recombinant allergen suitable for allergy and immunology research.
- Expressed in HEK293 cells with a C-terminal His tag.
- Approximately 19 kDa; sequence verified.
- Lyophilized from PBS (pH 7.4) for stability and convenience.
- Purity greater than 95% by reducing SDS-PAGE.
- Store lyophilized at -20°C; freeze aliquots for long-term storage.
- Recommended minimum reconstitution concentration 100 μg/mL in ddH2O.
Medchemexpress LLC Der p 23 protein (Dermatophagoides pteronyssinus) | >95.0% | 5 UG
Recombinant Der p 23 is the mature major allergen from the house dust mite Dermatophagoides pteronyssinus, provided lyophilized for laboratory use. The preparation corresponds to amino acids A22-T90, is expressed in HEK293 cells with a C-terminal His tag, and is supplied at 5 μg with >95% purity. It is intended for immunoassays, antibody production, and allergen characterization.
- Expressed in HEK293 cells for eukaryotic folding and modifications.
- C-terminal His tag facilitates detection and purification.
- Purity >95.0% as determined by reducing SDS-PAGE.
- Contains the mature region A22-T90, approx. 19 kDa.
- Lyophilized from PBS, pH 7.4, for increased stability.
- Supplied as 5 μg aliquots suitable for analytical assays.
- Store lyophilized at -20°C; aliquot and freeze for long-term storage.
- Suitable for immunoassays and antibody generation applications.
Medchemexpress LLC 5-(N,N-Hexamethylene)-amiloride | 1428-95-1 | 99.1% | 50 MG
5-(N,N-Hexamethylene)-amiloride is a derivative of amiloride and acts as a potent inhibitor of the Na+/H+ exchanger. This inhibition leads to a decrease in intracellular pH (pHi) and triggers apoptosis in leukemic cells. Additionally, it functions as an inhibitor of the HIV-1 Vpu virus ion channel. It has been shown to inhibit the replication of mouse hepatitis virus (MHV) and human coronavirus 229E (HCoV229E) in cultured L929 cells, with EC50 values of 3.91 μM and 1.34 μM, respectively.
- Potent Na+/H+ exchanger inhibitor.
- Decreases intracellular pH (pHi).
- Induces apoptosis in leukemic cells.
- Inhibits HIV-1 Vpu virus ion channel.
- Inhibits mouse hepatitis virus (MHV) replication.
- Inhibits human coronavirus 229E (HCoV229E) replication.
- Available in solid form, light yellow to yellow in color.
- Purity of 99.1%.