Nitrogen mustard compounds
Sigma Aldrich Bis(2-chloroethyl)amine hydrochloride
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich (3'-CHLORO-4'-METHYLBIPHENYL-4-YL)METHANAMINE HYDROCHLORIDE
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 4-Amino-7,8-dichloroquinoline
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich N(1)-(2-Methylphenyl)glycinamide hydrobromide
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 4-(4-Methylphenyl)-4-phenylpiperidine hydrochloride
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 2-morpholinonicotinaldehyde
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Selleck Chemical LLC Camonsertib-E1108-5MG
Camonsertib is a highly potent and selective inhibitor of ATR kinase with an IC50 of 1 nM
Medchemexpress LLC Flesinoxan | 98206-10-1 | 99.9% | 50 MG
Flesinoxan is a selective 5-HT1A receptor agonist research compound intended for laboratory research use. It is supplied as an off-white to light yellow solid with demonstrated potency at the 5-HT1A receptor and standard handling and storage recommendations for small-molecule research chemicals.
- Selective 5-HT1A receptor agonist (EC50 24 nM).
- High reported purity: 99.9%.
- Off-white to light yellow solid appearance.
- Soluble in DMSO (31.25 mg/mL); in vivo formulations reported at ≥2.08 mg/mL.
- Storage: powder stable at -20°C (3 years) and 4°C (2 years).
- For research use only; not for human consumption or clinical use.
Medchemexpress LLC Vu0467485 (AZ13713945) | 1451994-10-7 | 99.3% | 10 MG
VU0467485 (AZ13713945) is a potent, selective, orally bioavailable positive allosteric modulator (PAM) of the muscarinic acetylcholine receptor M4 supplied as a solid research reagent for preclinical studies.
- Potent and selective M4 receptor positive allosteric modulator.
- Orally bioavailable in preclinical models.
- High purity solid suitable for research applications.
- Provided in small milligram pack sizes for preclinical dosing.
- Molecular formula C17H17FN4O2S; molecular weight 360.41 g/mol.
Medchemexpress LLC ZL0580 | 2377151-10-3 | 99.4% | 532.53 | 50 MG
ZL0580 is a structurally similar analog of ZL0590. It induces epigenetic suppression of HIV by selectively binding to the BD1 domain of BRD4. This compound suppresses HIV by inhibiting Tat transactivation and transcription elongation, and by inducing repressive chromatin structure at the HIV promoter. It is intended for research use only.
- Induces epigenetic suppression of HIV
- Selectively binds to BD1 domain of BRD4
- Inhibits Tat transactivation and transcription elongation
- Induces repressive chromatin structure at the HIV promoter
- Demonstrates low toxicity at effective concentrations (e.g., 8 μM in PBMCs)
- Suppresses both PMA-stimulated and basal HIV transcription
- Shows almost complete loss of productive HIV infection in CD4+ T cells at 8 μM