Nitrogen mustard compounds
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Medchemexpress LLC HN37 | 1821222-10-9 | 99.5% | 340.39 g/mol | C20H21FN2O2 | 5 MG
HN37 is a small-molecule research compound that functions as a potent activator of the KCNQ2 potassium channel. It contains an alkyne moiety suitable for click-chemistry derivatization and is intended for in vitro pharmacology and chemical biology applications.
- Potent KCNQ2 activation with EC50 of 37 nM.
- Alkyne functional group suitable for copper-catalyzed azide-alkyne cycloaddition.
- High reported purity for reproducible assay performance.
- Soluble in DMSO at 50 mg/mL for preparation of concentrated stocks.
- Available in multiple milligram quantities for research use.
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Medchemexpress LLC Methyl (4-((4-fluorobenzyl)(prop-2-yn-1-yl)amino)-2,6-dimethylphenyl)carbamate | 1821222-10-9 | MFCD34676457 | 99.5% | C20H21FN2O2 | 10MG
HN37 is a small-molecule KCNQ2 (Kv7) activator intended for laboratory research use. It exhibits potent neuronal Kv7 activation with reported antiepileptic activity (EC50 ≈ 37 nM) and contains an alkyne functional group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and probe synthesis. The compound is provided as a high-purity solid or DMSO solution for experimental use.
- Potent KCNQ2 (Kv7) activator with EC50 ≈ 37 nM.
- Contains an alkyne group for CuAAC click chemistry.
- High purity (99.53%) suitable for research applications.
- Supplied in solid and DMSO solution formats.
- Intended for laboratory research only; not for human use.