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Primary amines

Organic compounds and functional groups that contain a basic nitrogen atom with a lone pair. Primary amines have a nitrogen atom bonded to two hydrogen atoms, and a carbon atom or other functional group.

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1

Medchemexpress LLC Hypaconine | 63238-68-6 | 469.57 | 5 MG
SDP

Hypaconine is a C19-diterpenoid alkaloid isolated from Aconitum and Delphinium spp. It exhibits strong cardiac activity and is for research use only.

  • Purity: 99.0%
  • Appearance: Solid, white to off-white
  • Molecular weight: 469.57
  • Molecular formula: C24H39NO8
  • CAS No.: 63238-68-6
  • For research use only

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2

Medchemexpress LLC Cuda | 479413-68-8 | 99.8% | 5 MG
SDP

Cuda is a small-molecule research reagent that functions as a potent inhibitor of soluble epoxide hydrolase (sEH) and a modulator of PPARα activity. It is supplied as a solid for laboratory research and has reported IC50 values of 11.1 nM (mouse sEH) and 112 nM (human sEH).

  • Potent sEH inhibitor with low-nanomolar activity in mouse
  • Modulates PPARα activity in cellular assays
  • High purity (99.8% as provided)
  • Available in small-mass quantities for screening and assay development
  • Store powder at -20°C for long-term stability

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3

Medchemexpress LLC Silydianin | 29782-68-1 | MFCD09970974 | 482.44 | 5 MG
SDP

Silydianin is a flavonolignan obtained from *Silybum marianum*. It inhibits PTP1B, monophenolase, and diphenolase of tyrosinase. Silydianin induces apoptosis and reduces cytokines (IL-4 and IL-5). It also exhibits antitumor activity against prostate cancer. As part of Silymarin, it contributes to antioxidant, cytoprotective, and immunomodulatory effects, and can be used in allergic asthma research.

  • Flavonolignan
  • Inhibits PTP1B
  • Inhibits monophenolase and diphenolase of tyrosinase
  • Induces apoptosis and reduces cytokines (IL-4 and IL-5)
  • Antioxidant, cytoprotective and immunomodulatory effects
  • Antitumor activity against prostate cancer
  • Used in allergic asthma research
  • Appearance: solid, white to off-white

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4

Medchemexpress LLC Hydrastinine hydrochloride | 4884-68-8 | 99.4% | 5 MG
SDP

Hydrastinine hydrochloride is a major alkaloid constituent found in goldenseal (Hydrastis canadensis). It functions as a haemostatic agent. Goldenseal, from which this compound is derived, has historically been used to treat various conditions, including gastrointestinal issues, urinary tract disorders, and inflammation.

  • Can be used as a haemostatic agent.

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5

Medchemexpress LLC ICCB-19 (hydrochloride) | 1803605-68-6 | 99.3% | 291.84 | C12H22ClN3OS | 5 MG
SDP

ICCB-19 hydrochloride is a research-grade small molecule that inhibits TRADD-mediated signaling and indirectly inhibits RIPK1 kinase activity. It has been reported to induce autophagy, modulate TNF-induced inflammatory responses, and affect RIPK1-dependent apoptosis in cellular and animal models.

  • Targets TRADD and indirectly inhibits RIPK1 kinase activity.
  • Binds TRADD N-terminal domain to disrupt protein interactions.
  • Promotes autophagy via K63-linked ubiquitination of Beclin-1.
  • Reduces TNF-induced inflammatory gene expression in cell and animal studies.
  • Provided as a hydrochloride salt with reported high purity.
  • Available as solid and DMSO solution aliquots for research use.

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