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Filtered Search Results
Medchemexpress LLC (3-([1,1'-Biphenyl]-2-ylethynyl)-1H-indazol-5-yl)(2,6-diazaspiro[3.5]nonan-2-yl)methanone | 3086536-23-1 | 99.5% | 446.54 | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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CDD-2807 is an inhibitor for serine/threonine kinase 33 (STK33) with an IC50 of 9.2 nM. It demonstrates no significant toxicity in mice and can penetrate the blood-testis barrier without accumulating in the brain. CDD-2807 induces a reversible contraceptive effect and has potential for the development of male contraception.
- Potent inhibitor of serine/threonine kinase 33 (STK33) with an IC50 of 9.2 nM.
- Can cross the blood-testis barrier.
- Exhibits no significant toxicity in mice.
- Does not accumulate in the brain.
- Induces a reversible contraceptive effect, suggesting potential for male contraceptive development.
- Intended for research use only.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 1620450-96-5 | 3-OXABICYCLO[3.1.0]HEXANE-6-CARBALDEHYDE | AstaTech | MFCD22690453 | 112.128 | C6H8O2 | 95.000 | O=CC1C2COCC12 | 0.25g | 200617364
3-OXABICYCLO[3.1.0]HEXANE-6-CARBALDEHYDE | AstaTech | 1620450-96-5 | MFCD22690453 | 112.128 | C6H8O2 | 95.000 | O=CC1C2COCC12 | 0.25g | 200617364
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 31255-26-2 | Bromo-PEG3-bromide | Ambeed | MFCD18205853 | 320.021 | C8H16Br2O3 | 96.000 | BrCCOCCOCCOCCBr | 100mg | 596329924
Bromo-PEG3-bromide | Ambeed | 31255-26-2 | MFCD18205853 | 320.021 | C8H16Br2O3 | 96.000 | BrCCOCCOCCOCCBr | 100mg | 596329924
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules Azido-PEG36-acid | Broadpharm |1701.000 | C75H149N3O38 | 0.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 50mg | 387754541
Azido-PEG36-acid | Broadpharm |1701.000 | C75H149N3O38 | 0.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 50mg | 387754541
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 111-46-6 | Diethylene glycol | Ambeed | MFCD00002882 | 106.121 | C4H10O3 | 99.000 | OCCOCCO | 25g | 517260819
Diethylene glycol | Ambeed | 111-46-6 | MFCD00002882 | 106.121 | C4H10O3 | 99.000 | OCCOCCO | 25g | 517260819
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Medchemexpress LLC EGTA-AM (EGTA Acetoxymethyl ester) | 99590-86-0 | 99.8% | 1 MG
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EGTA-AM is a membrane permeable form of EGTA, which can be passively loaded into cells to generate intracellular EGTA. It is also a Ca2+ chelator with slow chelating dynamics. For research use only.
- Membrane permeable, allowing passive loading into cells.
- Generates intracellular EGTA.
- Ca2+ chelator with slow chelating dynamics.
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Medchemexpress LLC Nonaethylene glycol 10g | 3386-18-3 | 414.49 g/mol | C18H38O10 | 10 G
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Nonaethylene glycol is a polyethylene glycol (PEG)-based PROTAC linker used as a hydrophilic, flexible spacer in the synthesis and optimization of bifunctional degrader molecules. The nine-unit ethylene glycol chain increases solubility and provides conformational freedom for connecting ligands or warheads.
- PEG-based linker with nine ethylene glycol units for flexibility.
- Enhances aqueous solubility of conjugates.
- Suitable for linker optimization in PROTAC synthesis.
- Available as a solid for routine synthetic workflows.
- Stable when stored under recommended conditions.
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Medchemexpress LLC Octaethylene glycol | 5117-19-1 | MFCD00698694 | 100.0% | 370.44 g/mol | C16H34O9 | 5 G
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Octaethylene glycol is a polyethylene glycol (PEG) linker composed of eight ethylene glycol units. It is a hydrophilic spacer used in chemical synthesis, commonly as a linker for proteolysis targeting chimeras (PROTACs) and other bioconjugation applications. The substance is a diol with terminal hydroxyl groups and is soluble in water and polar organic solvents.
- Cas number 5117-19-1.
- Molecular formula C16H34O9.
- Molecular weight 370.44 g/mol.
- High purity suitable for research use.
- Functional groups: terminal hydroxyls for conjugation.
- Uses: peg-based linker for PROTAC synthesis and bioconjugation.
- Available in small lab-scale quantities (5 G pack).
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eMolecules 1146169-44-9 | 4-[(2-methoxyethoxy)methyl]phenylboronic acid | Combi-Blocks | MFCD14687278 | 210.040 | C10H15BO4 | 98.000 | COCCOCc1ccc(cc1)B(O)O | 1g | 117529684
4-[(2-methoxyethoxy)methyl]phenylboronic acid | Combi-Blocks | 1146169-44-9 | MFCD14687278 | 210.040 | C10H15BO4 | 98.000 | COCCOCc1ccc(cc1)B(O)O | 1g | 117529684
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Medchemexpress LLC Hexaethylene glycol | 2615-15-8 | 99.5% | C12H26O7 | 10 G
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Hexaethylene glycol is a PEG-based PROTAC linker that plays a crucial role in the synthesis of PROTACs. These molecules are designed with two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other binding to a target protein. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of specific target proteins.
- Acts as a PEG-based PROTAC linker
- Utilized in the synthesis of PROTAC molecules
- Facilitates the degradation of target proteins via the ubiquitin-proteasome system
- For research use only
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Sigma Aldrich Fine Chemicals Biosciences 1,2-Dimethoxyethane | 110-71-4 | MFCD00008502 | 100ML
1,2-Dimethoxyethane | 110-71-4 | MFCD00008502 | 100ML ** For R&D use only. Not for drug, household, or other uses. CAS RN 110-71-4 is under an EPA TSCA Significant New Use Rule (40 CFR 721.10229). Website-reference: https://www.govinfo.gov/content/pkg/CFR-2018-title40-vol33/pdf/CFR-2018-title40-vol33-sec721-10229.pdf
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eMolecules 2089325-76-6 | 4-FLUOROTETRAHYDROFURAN-3-AMINE HYDROCHLORIDE | AstaTech141.570 | C4H9ClFNO | 95.000 | Cl.NC1COCC1F | 0.25g | 600864294
4-FLUOROTETRAHYDROFURAN-3-AMINE HYDROCHLORIDE | AstaTech | 2089325-76-6141.570 | C4H9ClFNO | 95.000 | Cl.NC1COCC1F | 0.25g | 600864294
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Medchemexpress LLC Hexyl nicotinate | 23597-82-2 | 99.0% | 100 MG
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Hexyl nicotinate is a nicotinic acid ester used as a laboratory reagent in biochemical and pharmacological research. It is typically supplied as a liquid with documented purity, molecular properties, and defined storage and solubility recommendations.
- Purity 98.96%.
- Molecular formula C12H17NO2.
- Molecular weight 207.27 g/mol.
- Appearance colorless to light yellow liquid; density 1.02 g/cm3.
- Solubility DMSO soluble at 100 mg/mL; in vivo formulation ≥ 2.5 mg/mL in 10% DMSO with SBE-β-CD in saline.
- Storage pure form: -20°C (3 years) or 4°C (2 years); in solvent: -80°C (6 months).
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eMolecules 50-81-7 | L-Ascorbic acid ACS reagent grade | Oakwood Chemical | MFCD00064328 | 176.124 | C6H8O6 | 99.000 | OC[C@H](O)[C@H]1OC(=O)C(O)=C1O | 500g | 537710429
L-Ascorbic acid ACS reagent grade | Oakwood Chemical | 50-81-7 | MFCD00064328 | 176.124 | C6H8O6 | 99.000 | OC[C@H](O)[C@H]1OC(=O)C(O)=C1O | 500g | 537710429
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eMolecules 33354-75-5 | ChemScene | 444-Trimethyl-2262-terpyridine | 100mg | 768992184 | CS-0086862 | MFCD06796994 | 275.355 | C18H17N3
Ambeed | 44-Dimethylisoxazolidin-3-one | 1g | 570579788 | A702965 | 81778-07-6 | MFCD21333197 | 115.132 | C5H9NO2
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