Sulfoxides
Medchemexpress LLC 3',4'-Tetramethylene-α-pyrrolidinobutiophenone (hydrochloride) | 2749504-65-0 | 99.9% | 307.86 | 50 MG
3',4'-Tetramethylene-α-pyrrolidinobutiophenone hydrochloride is structurally categorized as a drug derivative.
- Applications: Neuroscience-Neuromodulation
- Research area: Neurological disease
- Target: Drug derivative
Medchemexpress LLC Sodium butane-1-sulfonate | 2386-54-1 | MFCD00007540 | 98.0% | 160.17 g/mol | C4H9NaO3S | 500 MG
Sodium butane-1-sulfonate is the sodium salt of butane-1-sulfonic acid used as an ionic mobile-phase additive for chromatographic separation of arsenic, selenium, and related analytes. It appears as a white to off-white crystalline powder, supplied for research use, and is commonly used to improve ion-pairing and retention in aqueous chromatographic methods.
- Used as ionic mobile-phase additive for chromatographic separations.
- Improves separation and resolution of arsenic and selenium species.
- High purity suitable for analytical applications (manufacturer lists ~98% assay).
- White to off-white crystalline powder; stable and easy to weigh.
- Suits ion-pairing and retention control in aqueous methods.
Medchemexpress LLC CB2R/FAAH modulator-3 | 2876918-67-9 | C22H31NO2 | 50 MG
CB2R/FAAH modulator-3 (compound 27) is a dual-targeting modulator that acts as a CB2R agonist and FAAH inhibitor, with Ki values of 20.1 nM for CB2R and 67.6 nM for CB1R, and an IC50 value of 3.4 μM for FAAH. At 10 μM, it reduces the production of pro-inflammatory cytokines TNFα, IFN-γ, IL-1β, and IL6 in unstimulated monocytes and macrophages. This modulator can be used in studies related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.
- Molecular weight: 341.49
- Formula: C22H31NO2
- CAS no.: 2876918-67-9
- Appearance: Solid
- Color: White to off-white
- Purity: 99.71%
Medchemexpress LLC IL-17A modulator-3 | 2467732-95-0 | 99.37% | 639.80 | 5 MG
IL-17A modulator-3 (compound 253) is an IL-17A modulator. It inhibits IL-17A/A with an IC50 value of <10 μM. It can be used for the research of inflammation, cancer, and autoimmune diseases.
- Can be used for the research of inflammation
- Can be used for the research of cancer
- Can be used for the research of autoimmune diseases
Medchemexpress LLC CXCR7 modulator 2 | 2227426-37-9 | 98.71% | 522.68 | 1 ML
CXCR7 modulator 2 is a modulator of C-X-C Chemokine Receptor Type 7 (CXCR7), with a Ki of 13 nM. It is for research use only and not sold to patients. This modulator offers protection against cardiac injury.
- Potent CXCR7-binding affinity (Ki=13 nM).
- β-arrestin activity (EC50=11 nM).
- Improved selectivity in the GPCR panel.
- Improved therapeutic index in the hERG patch-clamp assay.
- Moderate to high in vitro turnover in NADPH-supplemented mouse-liver microsomes (MLM, 93 μL/min/mg) and hepatocytes (28 μL/min per million cells).
- Good aqueous solubility.
- Rapidly absorbed with a mean maximal plasma concentration (Cmax) of 682 ng/mL at 0.25 h (Tmax).
- Reduces cardiac fibrosis in an isoproterenol-induced cardiac injury model in mice.
Medchemexpress LLC CB2 modulator 1 | 666261-80-9 | 99.8% | 380.36 | C18H19F3N4O2 | 5 MG
CB2 modulator 1 is a potent small-molecule modulator of the cannabinoid receptor CB2 intended for research use. It has reported activity relevant to immune disorders, inflammation, osteoporosis, and renal ischemia. Supplied as a high-purity solid for in vitro and exploratory studies; follow appropriate safety and regulatory guidance.
- Acts on cannabinoid receptor CB2.
- Reported activity in immune disorders, inflammation, osteoporosis, and renal ischemia.
- CAS number 666261-80-9.
- Molecular formula C18H19F3N4O2.
- Molecular weight 380.36 g/mol.
- Purity 99.75% (reported).
- Available in small pack sizes for screening, e.g., 5 mg.
- Intended for research use only; follow appropriate safety guidance.