Sulfoxides
Medchemexpress LLC Sulindac-d3 | 99.4% | C20H14D3FO3S | 5 MG
Sulindac-d3 is a deuterium labeled non-steroidal anti-inflammatory agent that acts as a COX-2 inhibitor, inhibiting its overexpression. It is supplied as a light yellow to yellow solid.
- Deuterium labeled Sulindac
- Non-steroidal anti-inflammatory agent
- Acts as a COX-2 inhibitor
- Purity: 99.4% (HPLC)
- Isotopic enrichment: 99.8%
- Storage (powder): -20°C for 3 years
- Storage (in solvent): -80°C for 6 months; -20°C for 1 month
Medchemexpress LLC Kv3.1 modulator 2 | 3035827-42-7 | 99.8% | 437.88 | 5 MG
Kv3.1 modulator 2 (compound 4) is a Kv3.1 channels modulator with an EC50 value of 68 nM. This product is for research use only and is not sold to patients.
- Kv3.1 channels modulator
- EC50 value of 68 nM
Medchemexpress LLC mGluR3 modulator-1 | 374548-18-2 | MFCD01957075 | 98.7% | 271.36 g·mol⁻1 | C16H21N3O | 10 MG
mGluR3 modulator-1 is a small-molecule modulator of the metabotropic glutamate receptor 3 (mGluR3) intended for research use. It demonstrates activity in cellular calcium mobilization assays (EC50 = 1-10 μM) and is supplied with a reported high purity and defined molecular properties suitable for in vitro pharmacology and receptor profiling studies.
- Modulates mGluR3 receptor activity in cell-based assays.
- Demonstrated EC50 of 1-10 μM in HEK293T-mGluR-Gqi5 calcium mobilization assay.
- High purity suitable for research applications.
- Available in small mass packages for screening and assay work.
- Includes chemical identifiers for traceability, such as CAS 374548-18-2.
Medchemexpress LLC IL-17 modulator 4 | 2446803-65-0 | >99.0% | C27H34N6O2 | 1 MG
IL-17 modulator 4 is a proagent of IL-17 modulator 1, an orally active and highly efficacious IL-17 modulator. This compound is promising for the research of IL-17A mediated diseases, including inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome. It modulates IL-17A protein-protein interaction by stabilizing the conformation of the IL-17A dimer, preventing binding to the IL-17RA receptor and inhibiting the IL-17A-mediated signaling pathway. It demonstrates favorable pharmacokinetic properties with excellent oral bioavailability.
- Modulates IL-17A protein-protein interaction
- Stabilizes IL-17A dimer conformation
- Inhibits IL-17A-mediated signaling pathway
- Potential for research in inflammation and autoimmune diseases
- Exhibits good pharmacokinetic properties in rat models
- Offers high oral bioavailability
Medchemexpress LLC Hydrazinecarbothioamide, 2-(1H-indol-3-ylmethylene)-N-(4-methylphenyl)-, (2E)- | 2097787-75-0 | 99.0% | 308.40 | 50 MG
Nur77 modulator 3 is a chemical compound that acts as a modulator of the Nur77 receptor. Modulators are typically used in research to study receptor function and signaling pathways. This product is suitable for laboratory research and development applications.
- A chemical compound
- Used for receptor study
- Suitable for research applications
TARGETMOL CHEMICALS INC R-Sulforaphane 5MG
Also available in 1 mg, 2 mg, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. (R)-Sulforaphane (L-Sulforaphane) is a potent inducer of the Keap1/Nrf2/ARE pathway.
FOCUS BIOMOLECULES Biochemical Reagents, UHMCP1, Spliceosome modulator, CAS Unknown, 97% by HPLC/NMR (Conforms)
Biochemical Reagents, UHMCP1, Spliceosome modulator, CAS Unknown, 97% by HPLC/NMR (Conforms), UHMCP1 prevents the interaction (KD 80 uM) between the splicing factor SF3b155 and U2AF homology motif domain (UHM) U2AF65.1 The spliceosomal gene SF3B1 (which encodes for SF3b155) is frequently mutated in cancers as is the splicing factor U2AF.2 UHMCP1 displaying toxicity against HEK293 cells (EC50 140 uM) and various effects on pre-mRNA accumulation or intron retention, exon skipping and inclusion.1 An interesting new tool for study of the spliceosome.
Medchemexpress LLC Sodium decane-1-sulfonate | 13419-61-9 | 244.33 | 1 G
Sodium decane-1-sulfonate is an anionic surfactant primarily used for the analysis of organic small molecule compounds by HPLC and ion-pair liquid chromatography. It appears as a solid and is intended for research use only.
- Anionic surfactant
- Used for analysis of organic small molecule compounds
- Applicable in HPLC and ion-pair liquid chromatography
- Solid appearance
- For research use only
Medchemexpress LLC IL-17A modulator-3 | 2467732-95-0 | 99.37% | 639.80 | 25 MG
IL-17A modulator-3 (compound 253) is an IL-17A modulator that inhibits IL-17A/A with an IC50 value of less than 10 μM. This compound is suitable for research into inflammation, cancer, and autoimmune diseases.
- Inhibits IL-17A/A with an IC50 value of less than 10 μM
- Used for research on inflammation, cancer, and autoimmune diseases
- Molecular weight: 639.80
- Appearance: White to off-white solid
Medchemexpress LLC Sodium decane-1-sulfonate | 13419-61-9 | 244.33 | 5 G
Sodium decane-1-sulfonate is an anionic surfactant primarily used for the analysis of organic small molecule compounds via HPLC and ion-pair liquid chromatography. This product is intended for research use only and is not sold to patients.
- Anionic surfactant
- Used for analysis of organic small molecule compounds
- Applied in HPLC
- Applied in ion-pair liquid chromatography
- For research use only
Medchemexpress LLC Kv3.1 modulator 2 | 99.8% | 437.88 | 50 MG
Kv3.1 modulator 2 (compound 4) is a Kv3.1 channels modulator with an EC50 value of 68 nM. This modulator is suitable for laboratory research and studies involving Kv3.1 channels.
- Functions as a Kv3.1 channels modulator
- Has an EC50 value of 68 nM