Sulfoxides
Cayman Chemical Sulindac Inhibitors
An NSAID, a COX-2 inhibitor (IC50 = 0.79 µM), and a prodrug form of sulindac sulfide; selective for COX-2 over COX-1 (IC50 = >1,000 µM); inhibits acetic acid-induced writhing in mice and reduces carrageenan-induced paw edema in rats at 100 mg/kg; reduces tumor growth in a BxPC-3 mouse xenograft model at 60 mg/kg
Medchemexpress LLC Sonidegib metabolite 50mg | 1221722-10-6 | 296.24 g·mol⁻¹ | C15H11F3O3 | 50 MG
Sonidegib metabolite M48 (2-methyl-3-[4-(trifluoromethoxy)phenyl]benzoic acid) is the primary circulating metabolite of sonidegib, supplied as a research-grade reference standard for pharmacokinetic, metabolic, and analytical studies.
- For research use only; not for human or clinical use.
- High purity: 98.0%.
- White to off-white solid, stable under recommended storage.
- Comprehensive analytical data available (COA, HNMR, LC-MS).
- Recommended storage: room temperature (solid) for up to 3 years; in solvent: -80°C for 2 years, -20°C for 1 year.
- Suitable as a reference standard for PK and metabolism studies.
Cayman Chemical Sulforaphane Inhibitors
An isothiocyanate that potently induces chemopreventative enzymes via Keap1-Nrf2 signaling and ARE-driven gene expression; at 15 μM, inhibits class I and II HDAC activity and suppresses tumor growth selectively in cancerous prostate epithelial cells without affecting normal cells
Cayman Chemical SulIndac-d3 500ug
An internal standard for the quantification of sulindac by GC- or LC-MS
Medchemexpress LLC Mrgprx4 modulator-1 | 2492596-61-7 | 98.1% | C16H13ClF3NO3 | 10MG
MRGPRX4 modulator-1 is a small-molecule modulator of the Mas-related G-protein coupled receptor X4 used as a research tool for in vitro pharmacology and receptor signaling studies. It is supplied as a solid and as ready-to-use DMSO solutions, and is characterized by defined chemical identity, high purity, and documented storage recommendations.
- Modulates MRGPRX4 receptor activity in vitro.
- Available as solid and DMSO solution formats for flexible use.
- High purity suitable for research applications.
- Documented chemical identity (CAS 2492596-61-7) and formula C16H13ClF3NO3.
- Stable when stored under recommended conditions for extended shelf life.
Cayman Chemical Sulforaphane Inhibitors
An isothiocyanate that potently induces chemopreventative enzymes via Keap1-Nrf2 signaling and ARE-driven gene expression; at 15 μM, inhibits class I and II HDAC activity and suppresses tumor growth selectively in cancerous prostate epithelial cells without affecting normal cells