Sulfoxides
Medchemexpress LLC Sulindac sulfide | 49627-27-2 | MFCD00078044 | 98.1% | 1 ML
Sulindac sulfide is a noncompetitive γ-secretase inhibitor, demonstrating an IC50 of 20.2 μM for γ42-secretase activity. This compound is primarily utilized in neurological disease research, targeting drug metabolites and γ-secretase.
- Noncompetitive γ-secretase inhibitor
- IC50 of 20.2 μM for γ42-secretase activity
- Targeted for drug metabolite research
- Used in neurological disease studies
AdipoGen Prosulfocarb sulfoxide
Chemical. CAS 51954-81-5. Formula C14H21NO2S. MW 267.39. Metabolite of the herbicide Prosulfocarb. Can be used as a reference compound.
Medchemexpress LLC Sulindac sulfone | 59973-80-7 | 98.1% | 5 MG
Sulindac sulfone is an mTORC1 pathway inhibitor and a metabolite of Sulindac. It inhibits colon cancer cell growth and induces cell cycle arrest. Sulindac sulfone is utilized in cancer research.
- Cytotoxicity against human COLO320 cells after 72 hrs by WST-1 assay (IC50 > 200 μM)
- Cytotoxicity against human MIAPaCa2 cells after 72 hrs by WST-1 assay (IC50 > 200 μM)
Medchemexpress LLC (E/Z)-Sulindac sulfide | 32004-67-4 | MFCD00869764 | 99.88% | 250 MG
(E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM) that selectively reduces Aβ42 production in favor of shorter Aβ species. It can be used for researching Alzheimer's disease.
- Potent γ-secretase modulator (GSM).
- Selectively reduces Aβ42 production.
- Useful for Alzheimer's disease research.
Medchemexpress LLC Sulindac sulfide | 49627-27-2 | 98.10% | 250 MG
Sulindac sulfide is a noncompetitive γ-secretase inhibitor, demonstrating an IC50 of 20.2 μM for γ42-secretase activity. This compound is primarily used in research, especially for studying neurological diseases.
- Noncompetitive γ-secretase inhibitor
- IC50 of 20.2 μM for γ42-secretase activity
- Suitable for research applications
- Useful for studying neurological diseases
Medchemexpress LLC Elafibranor sulfoxide | 95.0% | 400.49 | C22H24O5S | 10 MG
Elafibranor sulfoxide is the sulfoxide metabolite of elafibranor supplied as a research-grade powder for in vitro and preclinical studies. It is intended for laboratory research use only and can be used to investigate PPAR-related pathways and metabolic disease models such as primary biliary cholangitis.
- Chemical formula C22H24O5S, molecular weight 400.49.
- Supplied as a powder; pack sizes include 10 MG.
- Purity (NMR): 95.0%.
- Target: PPAR; drug metabolite.
- Storage: powder -20°C for 3 years, 4°C for 2 years; in solvent -80°C for 6 months, -20°C for 1 month.
- Provided for research use only; not for human therapeutic use.
Medchemexpress LLC Cytochrome P450 2C9 antibody (YA2166) | 50 UL
Cytochrome P450 2C9 Antibody (YA2166) is a Rabbit-derived, non-conjugated IgG monoclonal antibody targeting Cytochrome P450 2C9. It is for research use only.
- Rabbit-derived IgG monoclonal antibody
- Targets Cytochrome P450 2C9
- Reactivity: Human
- Applications: WB (1:500-1:1000), ICC/IF (1:50-1:200), FC (1:50-1:100)
- Supplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol
- Storage at -20°C for 1 year, avoid repeated freeze/thaw cycles
![Medchemexpress LLC 2-bromo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]benzeneacetamide | 942296-18-6 | >98.0% | 298.13 g·mol⁻¹ | C12H12BrNO3 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000289913.png-250.jpg)
Medchemexpress LLC 2-bromo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]benzeneacetamide | 942296-18-6 | >98.0% | 298.13 g·mol⁻¹ | C12H12BrNO3 | 10 MG
AHL modulator-1 is a small-molecule research reagent that modulates N-acylated L-homoserine lactone (AHL)-mediated bacterial signalling. It is supplied as a high-purity solid for laboratory research and is not for human or animal therapeutic or diagnostic use.
- Modulates AHL-mediated bacterial signalling
- High purity (>98.0%)
- Molecular formula: C12H12BrNO3
- Molecular weight: 298.13 g·mol⁻¹
- Supplied as a 10 mg solid for research use only
Medchemexpress LLC Cytochrome P450 2E1 Antibody (YA2302) | 10 UL
Cytochrome P450 2E1 Antibody (YA2302) is a rabbit-derived, non-conjugated IgG monoclonal antibody that specifically targets Cytochrome P450 2E1. It is designed for research use and has applications in Western Blot (WB) for human, mouse, and rat species. This antibody is formulated in 10mM PBS, pH 7.4, containing 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide, and 50% glycerol.
- Monoclonal antibody targeting Cytochrome P450 2E1.
- Suitable for Western Blot (WB) applications.
- Reacts with human, mouse, and rat samples.
- Immunogen derived from human CYP2E1 aa52-114.
- Non-conjugated and unmodified.
Medchemexpress LLC Phenol, 2,2'-sulfinylbis[4,6-dichloro- | 844-26-8 | 99.0% | 372.05 | 50 MG
Bithionol sulfoxide is an anti-infection agent for parasites, with mutagenic activity. It can be used in research of parasite infections such as paragonimiasis, flukes, and cestodes infection.
- Shows toxicity to *Neoparamoeba spp* parasites in sea water.
- Exhibits mutagenic activity in strains TA98 and TA100.
- Demonstrates efficacy against natural rumen fluke infections in dairy cattle.
- Supplied as a white to off-white solid.
- Storage conditions for powder: -20°C for 3 years, 4°C for 2 years.
- Storage conditions in solvent: -80°C for 6 months, -20°C for 1 month.
eMolecules 5-Bromo-2-(methylsulfinyl)pyrimidine | 79685-17-9 | MFCD19689658 | 1g
Ambeed | 5-Bromo-2-(methylsulfinyl)pyrimidine | 1g | 600835143 | A245047 | | 79685-17-9 | MFCD19689658 | 221.070 | C5H5BrN2OS
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC Sirtuin modulator 3 50mg | 50mg
Sirtuin modulator 3 (compound 129) is a N-phenyl benzamide derivative acts as a sirtuin modulator[1]
Medchemexpress LLC Dl-sulforaphane n-acetyl-l-cysteine | 334829-66-2 | 99.9% | 340.48 g/mol | C11H20N2O4S3 | 5 MG
DL-Sulforaphane N-acetyl-L-cysteine is a sulforaphane metabolite used in research as an orally active histone deacetylase (HDAC) inhibitor. It is reported to have an extended half-life and improved blood-brain barrier permeability versus the parent compound, and has been used to study autophagy, HDAC activity, and anticancer mechanisms. Supplied as a high-purity solid for laboratory research.
- Orally active HDAC inhibitor and sulforaphane metabolite.
- Longer half-life and improved blood-brain barrier permeability compared with parent compound.
- Reported to induce autophagy, cell-cycle arrest, and apoptosis in certain cancer cell lines.
- High-purity solid suitable for research applications.
- Soluble in DMSO; store powder frozen for long-term stability.
Medchemexpress LLC Isavuconazonium sulfate | 946075-13-4 | MFCD27987905 | 97.1% | 814.84 g/mol | C35H36F2N8O9S2 | 1 ML
Isavuconazonium sulfate is the water-soluble prodrug of the antifungal isavuconazole, provided for research use. It is intended for biochemical and microbiological studies of invasive fungal pathogens and is supplied as a solid or as a ready-to-use 10 mM solution in DMSO, with supporting documentation for handling and quality.
- Water-soluble prodrug of isavuconazole.
- Suitable for in vitro studies of invasive fungal infections.
- Available as solid and as a 10 mM solution in DMSO.
- Purity 97.1% with COA and SDS available.
- Storage: powder at -20 °C; solution at -80 °C for extended stability.