Sulfoxides
Cayman Chemical Sulforaphane Inhibitors
An isothiocyanate that potently induces chemopreventative enzymes via Keap1-Nrf2 signaling and ARE-driven gene expression; at 15 μM, inhibits class I and II HDAC activity and suppresses tumor growth selectively in cancerous prostate epithelial cells without affecting normal cells
Medchemexpress LLC GLP-1R modulator C5 | 421578-93-0 | 99.8% | C24H21NO3 | 10MG
GLP-1R modulator C5 is a small-molecule allosteric modulator that enhances GLP-1 binding to the GLP-1 receptor via a transmembrane site. It is intended for research use and is characterized by an EC50 of 1.59 ± 0.53 μM, molecular formula C24H21NO3, and molecular weight 371.43 g·mol⁻1.
- Allosteric enhancer of GLP-1 binding to GLP-1R.
- Measured EC50 of 1.59 ± 0.53 μM.
- Available as solid (5-100 mg) and 10 mM solution in DMSO.
- High purity (99.81% by LCMS).
- Supplied with certificate of analysis for analytical verification.
Medchemexpress LLC Smurf1 modulator-1 | 1825371-51-4 | 99.8% | 446.54 | 5 MG
Smurf1 modulator-1 (Compound 20) is a selective inhibitor for Smad ubiquitination regulatory factor 1 (Smurf1), with IC50 of 180 nM.
- Selective inhibitor for Smad ubiquitination regulatory factor 1 (Smurf1) with an IC50 of 180 nM.
- For research use only.
Medchemexpress LLC Promethazine sulfoxide | 7640-51-9 | MFCD08063694 | 5mg
Promethazine sulfoxide is a metabolite of the histamine H1 receptor antagonist Promethazine (HY-B1296) It is formed from promethazine by the cytochrome P450 (CYP) isoform CYP2D6
Medchemexpress LLC Nourseothricin sulfate (streptothricin sulfate) | 96736-11-7 | 99.9% | 100 MG
Nourseothricin sulfate (Streptothricin sulfate) is a broad-spectrum antibiotic that destroys the outer membrane of Gram-negative bacteria and is a dominant selective marker for Fonsecaea pedrosoi. It inhibits protein biosynthesis in prokaryotic cells and strongly inhibits the growth of eukaryotes like fungi, and can also be used as a selective marker for a wide range of organisms including bacteria, yeast, filamentous fungi, and plant cells.
- Broad-spectrum antibiotic
- Destroys the outer membrane of Gram-negative bacteria
- Dominant selective marker for Fonsecaea pedrosoi
- Inhibits protein biosynthesis in prokaryotic cells
- Strongly inhibits the growth of eukaryotes like fungi
- Can be used as a selective marker for bacteria, yeast, filamentous fungi, and plant cells
Medchemexpress LLC DL-sulforaphane glutathione | 289711-21-3 | 484.61 g·mol⁻¹ | C16H28N4O7S3 | 5 MG
DL-Sulforaphane glutathione (DL-SFN-GSH) is the glutathione conjugate metabolite of sulforaphane, reported in rat plasma. It is supplied for research use and commonly used as an analytical reference in metabolic and pharmacokinetic studies to investigate sulforaphane biotransformation.
- Metabolite of sulforaphane identified in vivo.
- Suitable as an analytical standard for metabolic and PK studies.
- Provided in a small research pack for analytical applications.
- Chemical formula C16H28N4O7S3; molecular weight ~484.61 g·mol⁻¹.
- For research use only; not intended for human or clinical use.
Medchemexpress LLC IL-17 modulator 4 | 2446803-65-0 | 99.0% | C27H34N6O2 | 25 MG
IL-17 modulator 4 is a proagent of IL-17 modulator 1, an orally active and highly efficacious IL-17 modulator, promising for research into IL-17A mediated diseases like inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome.
- Proagent of an orally active, highly efficacious IL-17 modulator.
- Promising for research into IL-17A mediated diseases.
- Modulates IL-17A protein-protein interaction by stabilizing its conformation and preventing binding to the IL-17RA receptor.
- Inhibits the IL-17A-mediated signaling pathway and IL-8 secretion in HEKa cells (EC50 of 14 nM).
- Exhibits good pharmacokinetic properties in rat models (low clearance, moderate volume of distribution, 3.7 h half-life, 100% oral bioavailability).
- Appearance: solid, off-white to gray.
Medchemexpress LLC GLP-1R modulator L7-028 | 2648317-95-5 | 99.47% | C24H28N2O3 | 100 MG
GLP-1R modulator L7-028 is an allosteric modulator that enhances GLP-1 binding to GLP-1R via a transmembrane site (EC50 11.01 ± 2.73 μM). It is intended for research use only.
- Available as a solid, white to off-white in color.
- Soluble in DMSO at 100 mg/mL.
- Shipped at room temperature in continental US.
AdipoGen Prosulfocarb sulfoxide
Chemical. CAS 51954-81-5. Formula C14H21NO2S. MW 267.39. Metabolite of the herbicide Prosulfocarb. Can be used as a reference compound.
AdipoGen Prosulfocarb sulfoxide
Chemical. CAS 51954-81-5. Formula C14H21NO2S. MW 267.39. Metabolite of the herbicide Prosulfocarb. Can be used as a reference compound.