Sulfoxides
Medchemexpress LLC CRBN modulator-1 | 2407829-65-4 | 98.0% | 324.29 | 25 MG
CRBN modulator-1 is a Thalidomide analog and a CRBN modulator, extracted from WO2020006262A1, compound 10. It has an IC₅₀ of 3.5 μM and a Kᵢ of 0.98 μM. This product is for research use only.
- Thalidomide analog and CRBN modulator.
- IC₅₀ of 3.5 μM.
- Kᵢ of 0.98 μM.
- For research use only.
Medchemexpress LLC Cytochrome P450 17A1 Antibody (YA478) | 57 kDa | 100 UL
The Cytochrome P450 17A1 Antibody (YA478) from MedChemExpress is a rabbit-derived monoclonal antibody identified for laboratory research. Supplied as a liquid, it is stable under recommended storage conditions and formulated with TBS, BSA, glycerol, and sodium azide. This antibody is suitable for detecting Cytochrome P450 17A1 in human, mouse, and rat samples.
- Predicted and observed band size of 57 kDa
- Suitable for Western blot (WB), immunocytochemistry/immunofluorescence (ICC/IF), immunohistochemistry-paraffin (IHC-P), and flow cytometry (FC)
- Supplied at a concentration of 1.0 mg/mL
- Store at -20°C for up to 1 year
- Shipped with blue ice
Medchemexpress LLC N-(4-(4-(2-methoxyethoxy)phenyl)thiazol-2-yl)isoxazole-5-carboxamide | 2375779-31-8 | 99.3% | 345.37 g/mol | C16H15N3O4S | 10 MG
GP130 modulator-1 (compound A33) is a small-molecule modulator of the gp130 signaling pathway intended for research use in studies of inflammatory and degenerative disorders.
- Small-molecule gp130 signaling pathway modulator for research use.
- High purity: 99.3%.
- Molecular weight 345.37 g/mol.
- Chemical formula C16H15N3O4S.
- Available in multiple pack sizes, including 10 mg.
- Supplied as a light yellow to yellow solid for laboratory handling and storage.
TARGETMOL CHEMICALS INC SULINDAC SULFIDE 10MG
Also available in 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Sulindac sulfide (cis-Sulindac sulfide) is a non-steroidal anti-inflammatory compound that has a high affinity for COX-1 and acts as an inhibitor in Ras activation of Raf-1. Sulindac sulfide is a non-competitive inhibitor of gamma-secretase with an IC50 value of 20.2 uM. It is an active metabolite of sulinic acid. purity: 99%
Medchemexpress LLC 3',4'-Tetramethylene-α-pyrrolidinobutiophenone (hydrochloride) | 2749504-65-0 | 99.9% | 307.86 | 50 MG
3',4'-Tetramethylene-α-pyrrolidinobutiophenone hydrochloride is structurally categorized as a drug derivative.
- Applications: Neuroscience-Neuromodulation
- Research area: Neurological disease
- Target: Drug derivative
Medchemexpress LLC Triclabendazole sulfoxide | 100648-13-3 | 98.78% | 375.66 | 50 MG
Triclabendazole sulfoxide (TCBZ-SO) is the main plasma metabolite of Triclabendazole and exhibits anti-parasite effects. It can also inhibit the membrane transporter ABCG2/BCRP.
- Exhibits anti-parasite effects.
- Can inhibit membrane transporter ABCG2/BCRP.
- Available in different quantities to suit research needs.
- Purity of 98.78%.
- Multiple related antibodies and small molecules are also listed, indicating its use in various research areas such as anti-infection, membrane transporter/ion channel, protein tyrosine kinase/RTK, and parasitic infection.
Medchemexpress LLC Cytochrome P450 2C9 Antibody (YA2166) | 100 UL
Cytochrome P450 2C9 Antibody (YA2166) is a Rabbit-derived, non-conjugated IgG monoclonal antibody targeting Cytochrome P450 2C9. It is for research use only and is involved in the metabolism of various endogenous substrates, including fatty acids and steroids, contributing to the pharmacokinetic variability of drugs.
- Host: Rabbit
- Clonality: Recombinant, monoclonal
- Species reactivity: Human
- Conjugation: Non-conjugated
- Isotype: IgG
- Formulation: Supplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol
- Storage: Stored at -20°C for 1 year. Avoid repeated freeze/thaw cycles
- Shipping: Shipping with blue ice
- Application & dilution ratio: WB: 1:500-1:1000; ICC/IF: 1:50-1:200; FC: 1:50-1:100
Cayman Chemical GlycerophosphoNPalmitoyl Etha
Precursor of PEA, an endogenous CB found in brain, liver, and other mammalian tissues; PEA has potent anti-inflammatory activity in vivo
Cayman Chemical Sulindac sulfide
An active metabolite of sulindac; inhibits COX-1 and COX-2 (IC50s = 1.9 and 1.21 µM, respectively); inhibits aldose reductase (IC50 = 279 nM), blocking NADPH-dependent reduction of glucose to sorbitol, and reducing type 2 diabetic complications; inhibits colorectal cancer growth in vitro and in vivo
Cayman Chemical SulIndac sulfon 25mg
An oxidized metabolite of sulindac that is produced in many mammals but minimally in mice and rats; generally considered to be inactive against COX enzymes, although it can reduce azoxymethane-induced colon cancer in rats; inhibits aldose reductase (IC50 = 367 nM) in vitro