Sulfoxides
Medchemexpress LLC Cytochrome P450 3A4 Antibody (YA3715) | 50 UL
Cytochrome P450 3A4 (CYP3A4) is a cytochrome P450 monooxygenase extensively involved in the metabolism of various substrates, including sterols, steroid hormones, retinoids, and fatty acids. This protein utilizes molecular oxygen to hydroxylate carbon-hydrogen bonds and contributes significantly to androgen and cholesterol metabolism. It also plays a crucial role in retinoid metabolism by oxidizing all-trans-retinol to all-trans-retinal and is a major contributor to the oxidative metabolism of xenobiotics, influencing drug metabolism, vitamin D catabolism, and calcium homeostasis.
- Mouse-derived antibody
- Reacts with human, mouse, and rat samples
- Non-conjugated for broad application
- Formulated in PBS with 0.05% sodium azide
- Stable for 1 year when stored at -20°C
- Avoid repeated freeze/thaw cycles
- Applicable in WB, IHC-P, ICC/IF, FC, and ELISA experiments
- Liquid appearance
Medchemexpress LLC Cytochrome P450 3A4 Antibody (YA3715) | 10 UL
The CYP3A4 protein, a cytochrome P450 monooxygenase, is intricately involved in the metabolism of a diverse array of substrates, including sterols, steroid hormones, retinoids, and fatty acids. It plays a crucial role in various biological processes such as androgen and cholesterol metabolism, retinoid metabolism, and the oxidative metabolism of xenobiotics, acting as a major contributor to drug metabolism. This antibody also contributes to vitamin D catabolism and calcium homeostasis.
- Mouse-derived and non-conjugated IgG1 monoclonal antibody
- Targets Cytochrome P450 3A4
- Reactivity: Human, mouse, rat
- Formulated in PBS, pH 7.4
- Store at -20°C for 1 year
- Avoid repeated freeze / thaw cycles
- Liquid appearance
- Suitable for WB, IHC-P, ICC/IF, FC, ELISA applications
TARGETMOL CHEMICALS INC S1PR1 MODULATOR 1 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. S1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6. purity: 99%
Medchemexpress LLC 3',4'-tetramethylene-α-pyrrolidinobutiophenone (hydrochloride) | 2749504-65-0 | 99.9% | 307.86 g/mol | C18H26ClNO | 10 MG
3',4'-Tetramethylene-α-pyrrolidinobutiophenone hydrochloride is a synthetic research chemical classified as a drug derivative and intended for laboratory research use only. It is supplied as a white to off-white solid and is characterized by high purity according to manufacturer analytical data. Documentation such as a certificate of analysis and safety data sheet are provided.
eMolecules 67-68-5 | Dimethyl sulfoxide | Combi-Blocks | MFCD00002089 | 78.130 | C2H6OS | 95.000 | CS(C)=O | 5g | 388720131
Dimethyl sulfoxide | Combi-Blocks | 67-68-5 | MFCD00002089 | 78.130 | C2H6OS | 95.000 | CS(C)=O | 5g | 388720131
Medchemexpress LLC Cytochrome P450 2C9 antibody (YA2166) | 50 UL
Cytochrome P450 2C9 Antibody (YA2166) is a Rabbit-derived, non-conjugated IgG monoclonal antibody targeting Cytochrome P450 2C9. It is for research use only.
- Rabbit-derived IgG monoclonal antibody
- Targets Cytochrome P450 2C9
- Reactivity: Human
- Applications: WB (1:500-1:1000), ICC/IF (1:50-1:200), FC (1:50-1:100)
- Supplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol
- Storage at -20°C for 1 year, avoid repeated freeze/thaw cycles
Medchemexpress LLC Benzenepropanoic acid, 4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methyl- | 1050506-87-0 | 97.1% | C20H18ClNO3S | 1 ML
GPR120 modulator 2 is a chemical compound with a molecular formula of C20H18ClNO3S and a molecular weight of 387.88. This compound is a white to off-white solid and has a purity of 97.11% as determined by HPLC, with its mass spectrometry consistent with its structure.
- Molecular formula: C20H18ClNO3S
- Molecular weight: 387.88
- Appearance: White to off-white solid
- Purity (HPLC): 97.11%
- Mass spectrometry consistent with structure
Medchemexpress LLC IL-17A modulator-3 | 2467732-95-0 | 99.37% | 639.80 | 25 MG
IL-17A modulator-3 (compound 253) is an IL-17A modulator that inhibits IL-17A/A with an IC50 value of less than 10 μM. This compound is suitable for research into inflammation, cancer, and autoimmune diseases.
- Inhibits IL-17A/A with an IC50 value of less than 10 μM
- Used for research on inflammation, cancer, and autoimmune diseases
- Molecular weight: 639.80
- Appearance: White to off-white solid
Medchemexpress LLC GPR120 modulator 1 | 1050506-75-6 | 98.06% | C19H16ClNO4S | 50 MG
GPR120 modulator 1 is a G protein-coupled receptor 120 (GPR120) modulator, extracted from patent US8394841B2, compound example F1. It is intended for research use only and can be used for the study of diseases associated with abnormal or deregulated GPR120, such as diabetes.
- G protein-coupled receptor 120 (GPR120) modulator
- Extracted from patent US8394841B2, compound example F1
- Useful for research of diseases associated with abnormal or deregulated GPR120, such as diabetes
- For research use only
Medchemexpress LLC GLP-1R modulator C16 | 875005-43-9 | 98.7% | C21H26ClFN2O3 | 100 MG
GLP-1R modulator C16 is an allosteric modulator that enhances GLP-1 binding to GLP-1R via a transmembrane site with an EC50 of 8.43 ± 3.82 μM. It has a molecular weight of 408.89, appears as a solid with a white to off-white color, and is for research use only.
- Enhances GLP-1 binding to GLP-1R
- Allosteric modulator
- Molecular weight of 408.89
- Appears as a solid
- White to off-white color
- For research use only
Medchemexpress LLC Kv3.1 modulator 2 | 3035827-42-7 | 99.8% | 437.88 | 5 MG
Kv3.1 modulator 2 (compound 4) is a Kv3.1 channels modulator with an EC50 value of 68 nM. This product is for research use only and is not sold to patients.
- Kv3.1 channels modulator
- EC50 value of 68 nM
Medchemexpress LLC Cytochrome P450 24A1 Antibody (YA2121) | 10 UL
Cytochrome P450 24A1 Antibody (YA2121) is a non-conjugated, Rabbit-derived IgG monoclonal antibody, specifically designed to target Cytochrome P450 24A1. It is intended for research use only.
- Host: Rabbit
- Clonality: Recombinant, Monoclonal
- Species reactivity: Human
- Isotype: IgG
- Conjugation: Non-conjugated
- Formulation: Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
- Storage & stability: Stored at -20°C for 1 year, avoiding repeated freeze/thaw cycles.
- Applications: Western blot (WB) with a dilution ratio of 1:500-1:1000.
- Function: This cytochrome P450 monooxygenase is crucial for vitamin D catabolism and calcium homeostasis, inactivating calcidiol and calcitriol through C24- and C23-oxidation pathways.
- Subcellular localization: Mitochondrion