Sulfoxides
Medchemexpress LLC Sirtuin modulator 1 | 2070015-26-6 | MFCD29924722 | 99.9% | 10 MG
Sirtuin modulator 1 is a small-molecule modulator of SIRT1 (a homolog of SIRT3) reported with an EC1.5 of <1 μM and described in patent WO 2010071853 A1 (Compound No. 4). Supplied as a high-purity solid for research use, it is intended for biochemical and cellular studies of sirtuin activity.
- High reported purity for assay-ready use.
- Molecular formula C31H32ClN5O2S2, molecular weight 606.20 g/mol.
- CAS number 2070015-26-6 for unambiguous identification.
- Reported EC1.5 potency of <1 μM against SIRT1.
- Available in milligram-scale quantities suitable for research.
Medchemexpress LLC Triclabendazole sulfoxide (TCBZ-SO) | 100648-13-3 | 98.8% | 375.66 | 25 MG
Triclabendazole sulfoxide (TCBZ-SO) is the main plasma metabolite of Triclabendazole. It exhibits anti-parasite effects and can inhibit the membrane transporter ABCG2/BCRP.
- Main plasma metabolite of Triclabendazole
- Exhibits anti-parasite effects
- Inhibits the membrane transporter ABCG2/BCRP
- Useful in infection disease research
- Useful in cancer disease research
- Useful in parasitic infection research
Medchemexpress LLC Sirtuin modulator 3 50mg | 50mg
Sirtuin modulator 3 (compound 129) is a N-phenyl benzamide derivative acts as a sirtuin modulator[1]
Medchemexpress LLC GLP-1R modulator C16 | 875005-43-9 | 98.7% | C21H26ClFN2O3 | 50 MG
GLP-1R modulator C16 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 8.43 ± 3.82 μM).
- Enhances GLP-1 binding to GLP-1R.
- Acts via a transmembrane site.
- High purity of 98.7% confirmed by LCMS.
- Recommended storage conditions for powder: -20°C for 3 years, 4°C for 2 years.
- Recommended storage conditions for in solvent: -80°C for 6 months, -20°C for 1 month.
Medchemexpress LLC Kv3 modulator 2 | 2101321-76-8 | 99.9% | 379.41 g·mol⁻¹ | C21H21N3O4 | 5 MG
Kv3 modulator 2 is a small-molecule modulator of Kv3 voltage-gated potassium channels with reported analgesic activity. It is provided for laboratory research use and is characterized by a defined molecular formula and molecular weight, and high purity suitable for preclinical studies.
- High purity (99.9%).
- Available in small research quantities (example: 5 mg).
- Molecular formula C21H21N3O4; molecular weight 379.41 g·mol⁻¹.
- Reported Kv3 channel modulatory activity with analgesic effects.
- For research use only; not for human or clinical use.
Medchemexpress LLC Sirtuin modulator 3 10mg | 10mg
Sirtuin modulator 3 (compound 129) is a N-phenyl benzamide derivative acts as a sirtuin modulator[1]
Research Products International Corp 4Meth BDGalact 6 Sulf Sod 50MG
Fluorescent substrate for Morquio A Sulphatase.
- 4-Methylumbelliferone: <100PPM
![Medchemexpress LLC 4-Thiazolecarboxamide, 5-(3-methoxypropyl)-2-phenyl-N-[2-[6-(1-pyrrolidinylmethyl)thiazolo[5,4-b]pyridin-2-yl]phenyl]-,hydrochloride | 2070015-26-6 | 99.85% | 606.20 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000403398-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 4-Thiazolecarboxamide, 5-(3-methoxypropyl)-2-phenyl-N-[2-[6-(1-pyrrolidinylmethyl)thiazolo[5,4-b]pyridin-2-yl]phenyl]-,hydrochloride | 2070015-26-6 | 99.85% | 606.20 | 25 MG
Sirtuin modulator 1 is a modulator of SIRTl, a homolog of SIRT3, with EC1.5 of < 1 μM. It was extracted from patent WO 2010071853 A1, Compound No.4.
- Modulates SIRTl, a homolog of SIRT3.
- Has an EC1.5 of less than 1 μM.
- Extracted from patent WO 2010071853 A1.
- Identified as Compound No.4 in the patent.
Medchemexpress LLC Cytochrome P450 17A1 Antibody (YA478 | 57 kDa | 50 UL
The Cytochrome P450 17A1 Antibody (YA478) is a rabbit host antibody designed for research applications. It is supplied as a liquid with a concentration of 1.0 mg/mL and reacts with human, mouse, and rat samples.
- Reacts with human, mouse, and rat samples
- Suitable for Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, and Flow Cytometry
- Formulated in TBS (pH 7.4), 0.05% BSA, and 40% Glycerol
- Contains 0.05% Sodium Azide as a preservative
- Stable for 1 year when stored at -20°C
- Avoid repeated freeze/thaw cycles
Medchemexpress LLC 3-isoxazolecarboxamide, N-(2-cyclohexyl-2,3-dihydro-1,5-dimethyl-3-oxo-1H-pyrazol-4-yl)-4-methyl-5-... | 1825371-51-4 | 99.8% | 446.54 | 1 MG
Smurf1 modulator-1 (Compound 20) is a selective inhibitor for Smad ubiquitination regulatory factor 1 (Smurf1), with an IC50 of 180 nM. This product is for research use only and not sold to patients.
- Selective inhibitor for Smad ubiquiquitination regulatory factor 1 (Smurf1).
- IC50 of 180 nM.
- For research use only.
- Appearance is a white to off-white solid.
- Specific storage conditions for powder and in solvent.
- Soluble in DMSO.
![Medchemexpress LLC N-[(1S)-1-cycloheptyl-2-[4-[(2R)-3-(4-methylpiperazin-1-yl)-3-oxo-2-(propanoylamino)propyl]anilino] | 2467731-88-8 | 99.5% | C31H45N7O4 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000260756.png-250.jpg)
Medchemexpress LLC N-[(1S)-1-cycloheptyl-2-[4-[(2R)-3-(4-methylpiperazin-1-yl)-3-oxo-2-(propanoylamino)propyl]anilino] | 2467731-88-8 | 99.5% | C31H45N7O4 | 10MG
IL-17 modulator 3 is a small-molecule IL-17 pathway modulator intended for research use in studies of inflammation, cancer, and autoimmune diseases. It is provided as a chemically characterized research reagent with documentation of purity and structural identifiers suitable for in vitro and preclinical investigations.
- High purity (99.5%).
- Solid powder with light yellow to yellow appearance.
- Molecular formula C31H45N7O4 and molecular weight 579.73.
- Structural identifiers available (SMILES and PubChem CID documented).
- Supplied in a 10 mg quantity for laboratory research use.
- Intended for use in inflammation, cancer, and autoimmune disease research applications.
TARGETMOL CHEMICALS INC 5-HT1A MODULATOR 1 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. 5-HT1A modulator 1 displays very high affinities for the 5-HT1A (alpha)1-adrenergic receptor and D2 receptor (IC50s = 2 nM 10 nM and 40 nM). purity: 99%
Medchemexpress LLC (E/Z)-Sulindac sulfide | 32004-67-4 | 99.88% | 50 MG
(E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM) that selectively reduces Aβ42 production in favor of shorter Aβ species. It can be used for researching Alzheimer's disease.
- Potent γ-secretase modulator (GSM)
- Selectively reduces Aβ42 production
- Used for researching Alzheimer's disease
Medchemexpress LLC IL-17A modulator-1 | 2748749-29-1 | 98.8% | C33H31N5O4 | 25 MG
IL-17A modulator-1 is a compound that modulates the activity of IL-17A, an important cytokine involved in immune responses. Derived from patent WO2021239743+A1, this modulator inhibits the biological action of IL-17A with a pIC50 of 8.2, making it suitable for research into various diseases and disorders associated with IL-17A activity, including those with immune components, autoimmune pathologies, cancer, and neurodegenerative disorders. The product is provided as a white to off-white solid.
- Modulates IL-17A activity
- Inhibits biological action of IL-17A
- Suitable for research into immune, autoimmune, cancer, and neurodegenerative disorders
- White to off-white solid appearance
Cayman Chemical AM630 Other Receptor Modulator
An inverse agonist at CB2 and partial agonist at CB1 receptors; binds selectively to CB2 over CB1 receptors (Kis = 31.2 and 5,152 nM, respectively); blocks the antinociceptive effects of cannabinoids; decreases proliferation and induces cell cycle arrest in renal cell carcinoma cells