Sulfoxides
![Medchemexpress LLC Acetic acid, 2-[4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methylphenoxy]- | 1050506-75-6 | 98.1% | C19H16ClNO4S | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Acetic acid, 2-[4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methylphenoxy]- | 1050506-75-6 | 98.1% | C19H16ClNO4S | 1 ML
GPR120 modulator 1 is a G protein coupled receptor 120 (GPR120) modulator. This compound, extracted from patent US8394841B2 (compound example F1), is suitable for research into diseases linked to abnormal or deregulated GPR120, including diabetes.
- Modulates G protein coupled receptor 120 (GPR120)
- Supports research on diseases linked to GPR120 deregulation, such as diabetes
- Purity of 98.1% (HPLC)
- White to off-white solid appearance
- Chemical formula C19H16ClNO4S
Aobchem 6-Bromo-2-(methylsulfinyl)benzo[d]thiazole | 97% | C8H6BrNOS2 | 25g
6-Bromo-2-(methylsulfinyl)benzo[d]thiazole | 97% | C8H6BrNOS2 | 25g
Medchemexpress LLC Sulforaphane | 4478-93-7 | 99.75% | 177.29 | 200 MG
Sulforaphane is an orally active inducer of the Keap1/Nrf2/ARE pathway. It promotes the transcription of tumor-suppressing proteins and effectively inhibits the activity of HDACs. It protects the heart through the activation of the Keap1/Nrf2/ARE pathway and further induction of HO-1 expression. Sulforaphane suppresses high glucose-induced pancreatic cancer through AMPK-dependent signal transmission and exhibits both anticancer and anti-inflammatory properties.
- Targets: HDAC, Keap1-Nrf2, Apoptosis, Bcl-2 family, Caspase, Reactive oxygen species (ROS)
- Research areas: Inflammation/Immunology, Cancer
Aobchem Allyl(3 5-dimethoxyphenyl)sulfane | 97% | C11H14O2S | 250mg
Allyl(3 5-dimethoxyphenyl)sulfane | 97% | C11H14O2S | 250mg
Medchemexpress LLC 2H-Indol-2-one, 1,3-dihydro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1-(2-phenylethyl)- | 421578-93-0 | 99.81% | C24H21NO3 | 1 ML
GLP-1R modulator C5 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 1.59 ± 0.53 μM). This compound is for research use only.
- Allosteric modulator
- Enhances GLP-1 binding to GLP-1R
- Via a transmembrane site
Medchemexpress LLC Sodium decane-1-sulfonate | 13419-61-9 | MFCD00007526 | >98.0% | 244.33 | 10 G
Sodium decane-1-sulfonate is an anionic surfactant utilized for the analysis of organic small molecule compounds through HPLC and ion-pair liquid chromatography.
- Anionic surfactant
- Used for analysis of organic small molecule compounds
- Suitable for HPLC
- Suitable for ion-pair liquid chromatography
- Biochemical assay reagent
Medchemexpress LLC Sirtuin modulator 2 | 667910-69-2 | 99.2% | 349.41 | 25 MG
Sirtuin modulator 2 (Compound 132) is a sirtuin modulator exhibiting an ED50 equal to or less than 50 μM. It is intended for research use only. This compound is characterized by its molecular weight of 349.41 and appears as a light yellow to yellow solid.
- Appears as a light yellow to yellow solid.
- Has an ED50 equal to or less than 50 μM.
- Intended for research applications.
Medchemexpress LLC CB2R/FAAH modulator-3 | 2876918-67-9 | C22H31NO2 | 50 MG
CB2R/FAAH modulator-3 (compound 27) is a dual-targeting modulator that acts as a CB2R agonist and FAAH inhibitor, with Ki values of 20.1 nM for CB2R and 67.6 nM for CB1R, and an IC50 value of 3.4 μM for FAAH. At 10 μM, it reduces the production of pro-inflammatory cytokines TNFα, IFN-γ, IL-1β, and IL6 in unstimulated monocytes and macrophages. This modulator can be used in studies related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.
- Molecular weight: 341.49
- Formula: C22H31NO2
- CAS no.: 2876918-67-9
- Appearance: Solid
- Color: White to off-white
- Purity: 99.71%
Medchemexpress LLC YK-2168 | 2571068-74-9 | 98.05% | 315.80 | 50 MG
YK-2168 is a potent and selective CDK9 inhibitor with an IC50 of 5.9 nM. It inhibits the phosphorylation of the CDK9 substrate pS2-RNA Pol II C-terminal domain. YK-2168 induces apoptosis in tumor cells, suppresses the expression of CDK9-regulated genes such as MYC and Mcl1, and inhibits tumor growth in CDX mice models. This product can be used for cancer research, including leukemia.
- Potently inhibits purified CDK9 enzymatic activity
- Exhibits high selectivity over CDK1 and CDK2
- Inhibits proliferation of MV4-11 leukemia cells
- Induces dose-dependent inhibition of tumor growth in CDX mice models
- Suppresses CDK9-regulated gene expression
- Upregulates cleaved caspase 3, indicating induced apoptosis
- Maintains a good safety profile in vivo with no significant body weight changes
Aobchem (3-Isobutylphenyl)(methyl)sulfane | 95% | C11H16S | 500mg
(3-Isobutylphenyl)(methyl)sulfane | 95% | C11H16S | 500mg
TARGETMOL CHEMICALS INC CB2R/FAAH MODULATOR-3 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-3 acts as a CB2R agonist and FAAH inhibitor the Ki values are 20.1 and 67.6 nM for CB2R and CB1R respectively and the IC50 value for FAAH is 3.4 uM. CB2R/FAAH modulator-3 has research value related to cancer deleterious inflammatory cascades occurring in neurodegenerative diseases and COVID-19 infection. purity: 99%
Aobchem (2-Bromophenyl)(isopropyl)sulfane | ≥97% | CAS 245739-32-6 | C9H11BrS | 1g
(2-Bromophenyl)(isopropyl)sulfane | ≥97% | CAS 245739-32-6 | C9H11BrS | 1g
Medchemexpress LLC Kv3.1 modulator 2 | 3035827-42-7 | 99.8% | 437.88 | 25 MG
Kv3.1 modulator 2 is a Kv3.1 channels modulator with an EC50 value of 68 nM. It is for research use only and not sold to patients. This compound is a solid, appearing white to off-white, and has detailed storage and solubility protocols for various applications.
- Kv3.1 channels modulator
- EC50 value of 68 nM
- Solid, white to off-white appearance
- Specific storage recommendations for powder and in solvent
- Detailed solubility information for in vitro and in vivo use
Medchemexpress LLC CB2R/FAAH modulator-2 | 2876918-68-0 | C24H33NO2 | 1 ML
CB2R/FAAH modulator-2 is a dual targeting modulator functioning as a CB2R agonist and FAAH inhibitor. It has Ki values of 10.8 nM for CB2R and 152.9 nM for CB1R, and an IC50 value of 6.2 μM for FAAH. This modulator can be utilized in studies related to cancer, neurodegenerative diseases, and COVID-19 infection. In vitro, it has been shown to reduce the production of pro-inflammatory cytokines such as TNFα, IFN-γ, IL-1 ß, and IL6 in unstimulated monocytes and macrophages.
- Acts as a CB2R agonist
- Functions as a FAAH inhibitor
- Relevant for studies on cancer
- Useful in research on neurodegenerative diseases
- Applicable to COVID-19 infection studies
- Reduces production of pro-inflammatory cytokines