Sulfoxides
TARGETMOL CHEMICALS INC R-Sulforaphane 5MG
Also available in 1 mg, 2 mg, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. (R)-Sulforaphane (L-Sulforaphane) is a potent inducer of the Keap1/Nrf2/ARE pathway.
eMolecules 67-68-5 | Dimethyl sulfoxide | Combi-Blocks | MFCD00002089 | 78.130 | C2H6OS | 95.000 | CS(C)=O | 5g | 388720131
Dimethyl sulfoxide | Combi-Blocks | 67-68-5 | MFCD00002089 | 78.130 | C2H6OS | 95.000 | CS(C)=O | 5g | 388720131
Medchemexpress LLC Hydrazinecarbothioamide, 2-(1H-indol-3-ylmethylene)-N-(4-methylphenyl)-, (2E)- | 2097787-75-0 | 99.0% | 308.40 | 50 MG
Nur77 modulator 3 is a chemical compound that acts as a modulator of the Nur77 receptor. Modulators are typically used in research to study receptor function and signaling pathways. This product is suitable for laboratory research and development applications.
- A chemical compound
- Used for receptor study
- Suitable for research applications
Medchemexpress LLC Benzenepropanoic acid, 4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methyl- | 1050506-87-0 | 97.1% | C20H18ClNO3S | 1 ML
GPR120 modulator 2 is a chemical compound with a molecular formula of C20H18ClNO3S and a molecular weight of 387.88. This compound is a white to off-white solid and has a purity of 97.11% as determined by HPLC, with its mass spectrometry consistent with its structure.
- Molecular formula: C20H18ClNO3S
- Molecular weight: 387.88
- Appearance: White to off-white solid
- Purity (HPLC): 97.11%
- Mass spectrometry consistent with structure
Medchemexpress LLC IL-17A modulator-3 | 2467732-95-0 | 99.37% | 639.80 | 25 MG
IL-17A modulator-3 (compound 253) is an IL-17A modulator that inhibits IL-17A/A with an IC50 value of less than 10 μM. This compound is suitable for research into inflammation, cancer, and autoimmune diseases.
- Inhibits IL-17A/A with an IC50 value of less than 10 μM
- Used for research on inflammation, cancer, and autoimmune diseases
- Molecular weight: 639.80
- Appearance: White to off-white solid
Medchemexpress LLC Kv3.1 modulator 2 | 99.8% | 437.88 | 50 MG
Kv3.1 modulator 2 (compound 4) is a Kv3.1 channels modulator with an EC50 value of 68 nM. This modulator is suitable for laboratory research and studies involving Kv3.1 channels.
- Functions as a Kv3.1 channels modulator
- Has an EC50 value of 68 nM
Medchemexpress LLC YK-2168 | 2571068-74-9 | 98.1% | 315.80 | 25 MG
YK-2168 is a potent and selective CDK9 inhibitor with an IC50 of 5.9 nM. It inhibits phosphorylation of the CDK9 substrate pS2-RNA Pol II C-terminal domain. This compound induces apoptosis in tumor cells, suppresses the expression of CDK9-regulated genes, and inhibits tumor growth in CDX mice models. It is suitable for cancer research, including leukemia.
- Potent and selective CDK9 inhibitor (IC50 = 5.9 nM)
- Inhibits phosphorylation of the CDK9 substrate pS2-RNA Pol II C-terminal domain
- Induces apoptosis in tumor cells
- Suppresses expression of CDK9-regulated genes (e.g., MYC and Mcl1)
- Inhibits tumor growth in CDX mice models
- High selectivity over CDK1 and CDK2
- Does not inhibit hERG channel activity at concentrations up to 30 μM
- Demonstrates a good safety profile in animal models
Medchemexpress LLC GPR120 modulator 1 | 1050506-75-6 | 98.06% | C19H16ClNO4S | 50 MG
GPR120 modulator 1 is a G protein-coupled receptor 120 (GPR120) modulator, extracted from patent US8394841B2, compound example F1. It is intended for research use only and can be used for the study of diseases associated with abnormal or deregulated GPR120, such as diabetes.
- G protein-coupled receptor 120 (GPR120) modulator
- Extracted from patent US8394841B2, compound example F1
- Useful for research of diseases associated with abnormal or deregulated GPR120, such as diabetes
- For research use only
Medchemexpress LLC Elafibranor sulfoxide | 95.0% | 400.49 | 25 MG
Elafibranor (GFT505) sulfoxide is a sulfoxide metabolite of Elafibranor (HY-16737). Elafibranor is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively. Elafibranor can be used for the study of primary biliary cholangitis.
- Purity: 95.0%
- Molecular weight: 400.49
- Formula: C22H24O5S
- Appearance: Solid
- Color: Light yellow to yellow
- Solubility (in vitro): 100 mg/mL (DMSO)
- Storage (powder): -20°C 3 years, 4°C 2 years
- Storage (in solvent): -80°C 6 months, -20°C 1 month
- Research use only