Sulfoxides
Medchemexpress LLC Cytochrome P450 27A1 antibody (YA2163) | 100 UL
Cytochrome P450 27A1 Antibody (YA2163) is a rabbit-derived, non-conjugated IgG monoclonal antibody that targets Cytochrome P450 27A1. This enzyme plays a crucial role in cholesterol homeostasis by catalyzing the hydroxylation of cholesterol and its derivatives, leading to bile acid synthesis and modulation of lipid metabolism genes.
- Rabbit-derived monoclonal antibody
- Targets Cytochrome P450 27A1
- Non-conjugated IgG
- Reactive with human, mouse, and rat samples
- Purified by affinity chromatography
- Predicted band size: 60 kDa; Observed band size: 50 kDa
- Suitable for WB, IHC-P, ICC/IF, and FC applications
Medchemexpress LLC (R)-IL-17 modulator 4 | 2446804-29-9 | 99.6% | C27H34N6O2 | 25 MG
(R)-IL-17 modulator 4 is the R-configure of IL-17 modulator 4. This compound is a proagent of IL-17 modulator 1, an orally active, highly efficacious IL-17 modulator. It is promising for the research of IL-17A mediated diseases, including inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome.
- Target: IL-17
- Research applications include inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome
- Appearance: Solid
- Color: Off-white to gray
- Molecular weight: 474.60
- Solubility in DMSO: 100 mg/mL
![Medchemexpress LLC N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide | 476633-98-4 | 99.7% | 373.40 g·mol⁻1 | C22H19N3O3 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000287716.png-250.jpg)
Medchemexpress LLC N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide | 476633-98-4 | 99.7% | 373.40 g·mol⁻1 | C22H19N3O3 | 10 MG
Sirtuin modulator 6 is a small-molecule research compound that modulates sirtuin activity and is used in studies of lifespan, metabolic disorders, and neurodegenerative disease. The material is provided as a characterized solid with supporting batch documentation for research use in biochemical and cellular assays.
- High HPLC purity (99.7%).
- Molecular formula C22H19N3O3; molecular weight 373.40 g·mol⁻1.
- CAS registry number 476633-98-4 confirms chemical identity.
- Supplied in small research pack sizes suitable for assay preparation.
- Characterized by batch-specific COA and SDS for safety and quality data.
- Suitable for biochemical and cellular sirtuin pathway studies.
Medchemexpress LLC Sirtuin modulator 1 | 2070015-26-6 | 99.85% | 606.20 | 100 MG
Sirtuin modulator 1 is a compound that acts as a modulator of SIRTl, a homolog of SIRT3. This compound has an EC1.5 of less than 1 μM and was extracted from patent WO 2010071853 A1, Compound No.4.
- Modulator of SIRTl, a homolog of SIRT3
- High purity of 99.85%
- Solid appearance, light yellow to yellow color
- Molecular weight of 606.20
- Soluble in DMSO at 12.5 mg/mL
Medchemexpress LLC Triclabendazole sulfoxide | 100648-13-3 | MFCD09038493 | 98.8% | C14H9Cl3N2O2S | 10MG
Triclabendazole sulfoxide is the primary plasma metabolite of triclabendazole; it shows antiparasitic activity and has been reported to inhibit the ABCG2/BCRP transporter. Supplied for research use, it is typically used in pharmacology and transporter inhibition studies.
- Main plasma metabolite of triclabendazole.
- Exhibits antiparasitic activity.
- Inhibits ABCG2/BCRP transporter.
- Provided as a research-use reagent, not for human use.
- Stable under recommended cold storage conditions for extended periods.
Medchemexpress LLC Nourseothricin (sulfate) | 96736-11-7 | 99.9% | 500 MG
Nourseothricin (sulfate) is a broad-spectrum polycationic antibiotic that destroys the outer membrane of Gram-negative bacteria. It functions by inhibiting protein biosynthesis in prokaryotic cells and significantly suppressing the growth of eukaryotes such as fungi. It is a dominant selective marker for Fonsecaea pedrosoi and can be utilized as a selective marker for a diverse range of organisms, including bacteria, yeast, filamentous fungi, and plant cells.
- Broad-spectrum antibiotic
- Destroys outer membrane of Gram-negative bacteria
- Inhibits protein biosynthesis in prokaryotic cells
- Suppresses growth of eukaryotes such as fungi
- Selective marker for Fonsecaea pedrosoi, bacteria, yeast, filamentous fungi, and plant cells
- Mixture of several Streptothricins, mainly D and F
- Can create channels in the outer membrane of bacteria
Medchemexpress LLC CXCR7 modulator 2 | 2227426-37-9 | 98.7% | 522.68 | 100 MG
CXCR7 modulator 2 is a small molecule modulator of C-X-C Chemokine Receptor Type 7 (CXCR7) with a Ki of 13 nM. This compound exhibits potent CXCR7-binding affinity and β-arrestin activity, offering improved selectivity in GPCR panels and an enhanced therapeutic index in hERG patch-clamp assays. It demonstrates good aqueous solubility and is suitable for research applications.
- Potent CXCR7-binding affinity (Ki=13 nM)
- Beta-arrestin activity (EC50=11 nM)
- Improved selectivity in GPCR panel
- Improved therapeutic index in hERG patch-clamp assay
- Moderate to high in vitro turnover
- Good aqueous solubility
- Rapidly absorbed in vivo
- Reduces cardiac fibrosis in injury models
- Soluble in DMSO