Thioureas
![eMolecules 27231-36-3 | 2-Mercapto-5-methylbenzimidazole | Combi-Blocks | MFCD00010617 | 164.230 | C8H8N2S | 95.000 | Cc1ccc2[nH]c(S)nc2c1 | 1g | 290687361](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502184018.JPG-250.jpg)
eMolecules 27231-36-3 | 2-Mercapto-5-methylbenzimidazole | Combi-Blocks | MFCD00010617 | 164.230 | C8H8N2S | 95.000 | Cc1ccc2[nH]c(S)nc2c1 | 1g | 290687361
2-Mercapto-5-methylbenzimidazole | Combi-Blocks | 27231-36-3 | MFCD00010617 | 164.230 | C8H8N2S | 95.000 | Cc1ccc2[nH]c(S)nc2c1 | 1g | 290687361
AdipoGen Z-Leu-Arg-Gly-Gly-AMC
Chemical. CAS 167698-68-2 free base. Formula C34H44N8O8 . C2HF3O2. MW 692.8 . 114.0. Fluorogenic tetrapeptide substrate for ubiquitin C-terminal hydrolases UCHs, e.g. UCHL3 and isopeptidase T. LRGG is the preferred substrate sequence of the human deSUMOylating enzymes SENP6 and SENP7. Excitation 380nm. Emission 460nm.
Biomatik Corporation Leupeptin, Hemisulfate Salt. Grade Biotechnology. Storage -20C. CAS 103476-89-7
Leupeptin, Hemisulfate Salt. Grade Biotechnology. Storage -20C. CAS 103476-89-7
AdipoGen Z-Leu-Leu-Phe-CHO
Chemical. CAS 133429-58-0. Formula C29H39N3O5. MW 509.7. Reversible and cell permeable proteasome inhibitor. Specifically inhibits the chymotrypsin-like activity of the proteasome. Calpain and cathepsin inhibitor. Does not inhibit the peptidyl-glutamyl peptide hydrolyzing activity of MPC.
Chem-Impex International, Inc. N-(2-Pyridinyl)thiourea | MFCD00041227 | 5G
N-(2-Pyridinyl)thiourea, MFCD00041227, 5G
AdipoGen Suc-Leu-Tyr-AMC
Chemical. CAS 94367-20-1. Formula C29H33N3O8. MW 551.6. Fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome. Fluorogenic substrate for calpain and papain. Peptide substrate for Ti protease from E.coli. Excitation 360nm. Emission 460nm. This substrate is useful for inhibitor screening and kinetic analysis.
AdipoGen Desacetylcolchicine tartrate
Chemical. CAS 49720-72-1. Formula C20H23NO5 . C4H6O6. MW 357.4 . 150.1. Synthetic. Anticancer colchicine analog. Microtubule polymerization inhibitor. Prevents cell division.
eMolecules 6972-05-0 | 1,1-DIMETHYL-THIOUREA | AstaTech | MFCD00060474 | 104.170 | C3H8N2S | 95.000 | CN(C)C(N)=S | 0.25g | 402181171
1,1-DIMETHYL-THIOUREA | AstaTech | 6972-05-0 | MFCD00060474 | 104.170 | C3H8N2S | 95.000 | CN(C)C(N)=S | 0.25g | 402181171
AdipoGen GSH-OEt
Chemical. CAS 92614-59-0. Formula C12H21N3O6S. MW 335.38. Synthetic. GSH-OEt is cellpermeable and has been used to protect cells against radiation damage, oxidants and various toxic compounds including heavy metals. GSH-OEt is a protective agent against cellular damage, such as cataracts and mitochondrial degeneration. It undergoes hydrolysis by intracellular esterases thereby increasing intracellular GSH concentration in many tissues and cell types. Glutathione monoethyl ester may be used to supplement cellular pools of GSH in vitro and in vivo and can prevent ROS formation, neutralize toxic products and block apoptosis pathway. The effect of glutathione GSH and glutathione ethyl ester GSH-OEt supplementation on GSH homeostasis and exercise-induced oxidative stress was also examined. Glutathione ethyl ester protects against cisplatin-induced ototoxicity in the rat.
![Sigma Aldrich Fine Chemicals Biosciences [beta-Mercapto-beta,beta-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-Oxytocin >=93% (HPLC), solid | 77327-45-8 | MFCD00135712 | 1MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501769998.PNG-250.jpg)
Sigma Aldrich Fine Chemicals Biosciences [beta-Mercapto-beta,beta-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-Oxytocin >=93% (HPLC), solid | 77327-45-8 | MFCD00135712 | 1MG
[beta-Mercapto-beta,beta-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-Oxytocin >=93% (HPLC), solid | Purity: >=93% (HPLC) | Mol Wt: 1075.3 | 77327-45-8 | MFCD00135712 | 1MG
Matrix Scientific 1,3-DIBUTYL-2-THIOUREA-250G
1,3-Dibutyl-2-thiourea, 250g,C9H20N2S, MFCD00004926, mw 188.34, [109-46-6]
AdipoGen Colcemid
Chemical. CAS 477-30-5. Formula C21H25NO5. MW 371.43. Synthetic. Depolymerizes microtubules and blocks mitosis at metaphase. Often in karyotyping and cell cycle research it is desirable to increase the yield of mitotic cells in a particular phase of the cell cycle. This can be achieved in a variety of ways with the most popular being the use of a cell cycle synchronizing agent such as demecolcine. Demecolcine will arrest cells in metaphase with no remarkable effect on the biochemical events in mitotic cells or in synchronized G1 and S phase cells. White blood cells are often treated with demecolcine to arrest cells in metaphase.
AdipoGen Aluminon
Chemical. CAS 569-58-4. Formula C22H14O9 . 3NH3. MW 422.3 . 51.1. Synthetic. Aluminon, the triammonium salt of aurintricarboxylic acid, is a dye commonly used to detect the presence of the aluminium ion in an aqueous solution. In addition to its use in qualitative inorganic analysis, aluminon has applications in pigment production. It forms brilliantly colored lake pigments with aluminum, chromium, iron and beryllium. Spectral data AL-Complex Absorbance at ~525nm. Aurintricarboxylic acid readily polymerizes in aqueous solution, forming a stable free radical that inhibits protein-nucleic acid interactions. It is a potent inhibitor of RNA-directed DNA polymerase and topoisomerase II. Angiogenesis inhibitor. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells.
AdipoGen Triptolide
Chemical. CAS 38748-32-2. Formula C20H24O6. MW 360.4. Synthetic. Potent immunosuppressant with anti-inflammatory and antitumor properties. Exhibits potent antiproliferative activity, induces apoptosis, modulates autophagy and inhibits cell cycle regulators. Inhibits global gene transcription by inducing degradation of RNA polymerase II Pol II and by inhibiting the ATPase activity of XPB a subunit of the general transcription factor TFIIH. Interferes with a number of transcription factors including p53, NF-kappaB, nuclear factor of activated T cells NFAT and heat shock factor protein 1 HSF-1. Shown to inhibit aromatase activity.