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Filtered Search Results
eMolecules 18741-24-7 | 2-Mercapto-3-phenylquinazolin-4-one | Oakwood Chemical | MFCD00023895 | 254.310 | C14H10N2OS | 95.000 | O=c1n(-c2ccccc2)c(=S)[nH]c2ccccc12 | 100mg | 537713488
2-Mercapto-3-phenylquinazolin-4-one | Oakwood Chemical | 18741-24-7 | MFCD00023895 | 254.310 | C14H10N2OS | 95.000 | O=c1n(-c2ccccc2)c(=S)[nH]c2ccccc12 | 100mg | 537713488
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eMolecules (2-Hydroxyphenyl)thiourea | 1520-26-9 | MFCD00041159 | 1g
Combi-Blocks | (2-Hydroxyphenyl)thiourea | 1g | 232333878 | SH-5742 | 98.000 | 1520-26-9 | MFCD00041159 | 168.210 | C7H8N2OS
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eMolecules 62-56-6 | THIOUREA | Broadpharm | MFCD00008067 | 76.120 | CH4N2S | 99.000 | NC(N)=S | 500g | 249969213
THIOUREA | Broadpharm | 62-56-6 | MFCD00008067 | 76.120 | CH4N2S | 99.000 | NC(N)=S | 500g | 249969213
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eMolecules 62-56-6 | Thiourea | Oakwood Chemicals | MFCD00008067 | 76.120 | CH4N2S | 99.000 | NC(N)=S | 5g | 480131779
Thiourea | Oakwood Chemicals | 62-56-6 | MFCD00008067 | 76.120 | CH4N2S | 99.000 | NC(N)=S | 5g | 480131779
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eMolecules 62-56-6 | Thiourea | Combi-Blocks | MFCD00008067 | 76.120 | CH4N2S | 98.000 | NC(N)=S | 100g | 290691754
Thiourea | Combi-Blocks | 62-56-6 | MFCD00008067 | 76.120 | CH4N2S | 98.000 | NC(N)=S | 100g | 290691754
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AdipoGen Colcemid
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Chemical. CAS 477-30-5. Formula C21H25NO5. MW 371.43. Synthetic. Depolymerizes microtubules and blocks mitosis at metaphase. Often in karyotyping and cell cycle research it is desirable to increase the yield of mitotic cells in a particular phase of the cell cycle. This can be achieved in a variety of ways with the most popular being the use of a cell cycle synchronizing agent such as demecolcine. Demecolcine will arrest cells in metaphase with no remarkable effect on the biochemical events in mitotic cells or in synchronized G1 and S phase cells. White blood cells are often treated with demecolcine to arrest cells in metaphase.
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AdipoGen Aluminon
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Chemical. CAS 569-58-4. Formula C22H14O9 . 3NH3. MW 422.3 . 51.1. Synthetic. Aluminon, the triammonium salt of aurintricarboxylic acid, is a dye commonly used to detect the presence of the aluminium ion in an aqueous solution. In addition to its use in qualitative inorganic analysis, aluminon has applications in pigment production. It forms brilliantly colored lake pigments with aluminum, chromium, iron and beryllium. Spectral data AL-Complex Absorbance at ~525nm. Aurintricarboxylic acid readily polymerizes in aqueous solution, forming a stable free radical that inhibits protein-nucleic acid interactions. It is a potent inhibitor of RNA-directed DNA polymerase and topoisomerase II. Angiogenesis inhibitor. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells.
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AdipoGen TPEN
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Chemical. CAS 16858-02-9. Formula C26H28N6. MW 424.5. TPEN is a cell permeable metal ion chelator. TPEN is a chelator that has a high affinity for zinc Zn2, next to other transition metals Zn2 >Fe2 >Mn2 and is used in zinc treatment studies to limit intra- and extracellular concentrations of the mineral. TPEN has lower affinity for Ca2 and Mg2 and can also form complexes with other soft metal ions such as Cd2. In addition to a heavy metal chelator, TPEN is also known to be an apoptosis inducer. Depletion of zinc by TPEN induces apoptosis in several cell lines. TPEN shows anticancer activity through induction of caspase-dependent apoptosis, via reactive oxygen species ROS signaling mechanism and inhibiting cell autophagy. TPEN also inhibits RNA binding protein Lin28 and has been shown to be useful in extracting Abeta depostis from Alzheimers disease brain tissue.
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AdipoGen Z-Leu-Leu-Leu-AMC
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Chemical. CAS 152015-61-7. Formula C36H48N4O7. MW 648.8. Fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome. Excitation 345nm. Emission 445nm. This substrate is useful for inhibitor screening and kinetic analysis.
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AdipoGen Budesonide
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Chemical. CAS 51333-22-3. Formula C25H34O6. MW 430.5. Budesonide is a glucocorticoid and an agonist of glucocorticoid receptors EC50=45.7pM in a transactivation assay, selective for glucocorticoid over mineralocorticoid receptors. Budesonide is a synthetic anti-inflammatory agent that displays chemopreventive activity. It is used as an anti-inflammatory agent in the treatment of asthma, rhinitis and inflammatory bowel disease and is evaluated in prevention of lung cancer. It prevents formation of lung adenomas and adenocarcinomas in mice following inhalation or oral administration. It also reverses DNA hypomethylation and modulates expression of cancer related genes. Due to its potent activity, as an inhaled glucocorticoid, in reducing airway inflammation, Budesonide has potential as treatment for early COVID-19 infection.
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eMolecules 62-56-6 | Thiourea | Chem-Impex | MFCD00008067 | 76.120 | CH4N2S | 99.000 | NC(N)=S | 25kg | 342448904
Thiourea | Chem-Impex | 62-56-6 | MFCD00008067 | 76.120 | CH4N2S | 99.000 | NC(N)=S | 25kg | 342448904
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Biomatik Corporation Pepstatin A. Grade High Purity. Storage 4C. CAS 8913806
Pepstatin A. Grade High Purity. Storage 4C. CAS 8913806
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AdipoGen Ozagrel
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Chemical. CAS 82571-53-7. Formula C13H12N2O2. MW 228.2. Synthetic. Ozagrel, an antithrombic drug, is a potent and selective TXA Synthase thromboxane A2 TXAS inhibitor. Acts as a selective inhibitor of TXAS with an IC50=11nM. The beneficial effects of TXAS inhibition by ozagrel include improved motor coordination after experimental stroke, and antihypertensive effects in spontaneously hypertensive rats.
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AdipoGen Z-Leu-Arg-Gly-Gly-AMC
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Chemical. CAS 167698-68-2 free base. Formula C34H44N8O8 . C2HF3O2. MW 692.8 . 114.0. Fluorogenic tetrapeptide substrate for ubiquitin C-terminal hydrolases UCHs, e.g. UCHL3 and isopeptidase T. LRGG is the preferred substrate sequence of the human deSUMOylating enzymes SENP6 and SENP7. Excitation 380nm. Emission 460nm.
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AdipoGen Pifithrin-alpha HBr
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Chemical. CAS 63208-82-2. Formula C16H18N2OS . HBr. MW 286.4 . 80.9. p53 inhibitor. Reversibly blocks p53-dependent transcriptional activation. Tool to combat side effects of cancer therapy. Apoptosis inhibitor.
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