Anthracyclines
Doxorubicin hydrochloride, MP Biomedicals™
CAS: 25316-40-9 Molecular Formula: C27H30ClNO11 Molecular Weight (g/mol): 579.98 MDL Number: MFCD00077757,MFCD00077757,MFCD00941448 InChI Key: MWWSFMDVAYGXBV-FGBJBKNOSA-N Synonym: doxorubicin hydrochloride,adriamycin,doxorubicin hcl,adriacin,adriblastina,rubex,adriamycin hydrochloride,adriblastin,adriamycin pfs PubChem CID: 129626538 IUPAC Name: hydrogen (8S,10S)-10-[(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy]-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione chloride SMILES: [H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
Doxorubicin hydrochloride
CAS: 25316-40-9 Molecular Formula: C27H30ClNO11 Molecular Weight (g/mol): 579.98 MDL Number: MFCD00077757,MFCD00077757,MFCD00941448 InChI Key: MWWSFMDVAYGXBV-FGBJBKNOSA-N Synonym: doxorubicin hydrochloride,adriamycin,doxorubicin hcl,adriacin,adriblastina,rubex,adriamycin hydrochloride,adriblastin,adriamycin pfs PubChem CID: 129626538 IUPAC Name: hydrogen (8S,10S)-10-[(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy]-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione chloride SMILES: [H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
Daunorubicin hydrochloride
CAS: 23541-50-6 Molecular Formula: C27H30ClNO10 Molecular Weight (g/mol): 563.984 MDL Number: MFCD04974507 InChI Key: GUGHGUXZJWAIAS-QQYBVWGSSA-N Synonym: daunorubicin hydrochloride,daunorubicin hcl,daunomycin hydrochloride,daunoblastina,rubidomycin hydrochloride,daunorubicinol hydrochloride,daunoblastin,rubomycin,ondena,daunomycin chlorohydrate PubChem CID: 62770 IUPAC Name: (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride SMILES: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)C)O)N)O.Cl
Doxorubicin Hydrochloride 95.0+%, TCI America™
CAS: 25316-40-9 Molecular Formula: C27H30ClNO11 Molecular Weight (g/mol): 579.98 MDL Number: MFCD00077757,MFCD00077757,MFCD00941448 InChI Key: MWWSFMDVAYGXBV-FGBJBKNOSA-N Synonym: doxorubicin hydrochloride,adriamycin,doxorubicin hcl,adriacin,adriblastina,rubex,adriamycin hydrochloride,adriblastin,adriamycin pfs PubChem CID: 129626538 IUPAC Name: hydrogen (8S,10S)-10-[(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy]-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione chloride SMILES: [H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
Daunorubicin Hydrochloride 98.0+%, TCI America™
CAS: 23541-50-6 Molecular Formula: C27H30ClNO10 Molecular Weight (g/mol): 563.984 MDL Number: MFCD04974507 InChI Key: GUGHGUXZJWAIAS-QQYBVWGSSA-N Synonym: daunorubicin hydrochloride,daunorubicin hcl,daunomycin hydrochloride,daunoblastina,rubidomycin hydrochloride,daunorubicinol hydrochloride,daunoblastin,rubomycin,ondena,daunomycin chlorohydrate PubChem CID: 62770 IUPAC Name: (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride SMILES: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)C)O)N)O.Cl
Selleck Chemical LLC Doxorubicin (DOX) HCl S1208-1g
Doxorubicin (DOX) HCl is an antibiotic agent that inhibits human DNA topoisomerase I and topoisomerase II with IC50s of 0 8 M and 2 67 M respectively Doxorubicin reduces basal phosphorylation of AMPK Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation This product may precipitate when dissolved in PBS solution It is recommended to prepare the stock solution in pure water and dilute with either pure water or saline to obtain the working solution Doxorubicin (Adriamycin) HCl can be used to induce animal models of kidney disease
Sigma Aldrich Fine Chemicals Biosciences Daunorubicin hydrochloride >=90% (HPLC) | 23541-50-6 | MFCD04974507 | 5MG
Daunorubicin hydrochloride >=90% (HPLC) | Purity: >=90% (HPLC) | Mol Wt: 563.98 | 23541-50-6 | MFCD04974507 | 5MG
Sigma Aldrich Fine Chemicals Biosciences Apoatropine hydrochloride10MG
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity water residual solvents inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH Co. KG
TARGETMOL CHEMICALS INC DAUNORUBICIN HYDROCHLORI 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Daunorubicin hydrochloride (Rubidomycin hydrochloride) an anthracycline aminoglycoside antineoplastic inhibits DNA replication and repair and RNA and protein synthesis. purity: 99%
Sigma Aldrich Fine Chemicals Biosciences Naltrindole hydrochloride50MG
Naltrindole hydrochloride50MG
Medchemexpress LLC Doxorubicin hydrochloride | 25316-40-9 | MFCD00077757 | 99.3% | 579.98 g/mol | C27H30ClNO11 | 10 MG
Doxorubicin hydrochloride is an anthracycline antibiotic with cytotoxic activity supplied as a high-purity analytical standard for laboratory research. It functions as a DNA intercalator and inhibits topoisomerases I and II, making it useful as a biochemical reagent and reference in cell-based assays and analytical method development.
- High purity (99.33%) suitable for analytical applications.
- Confirmed identity: CAS 25316-40-9, molecular weight 579.98 g/mol.
- Available in multiple package sizes, including 10 mg.
- Acts as a DNA intercalator and topoisomerase I/II inhibitor.
- Suitable for biochemical assays, cell-based studies, and analytical standards.
Medchemexpress LLC Doxorubicin hydrochloride | 25316-40-9 | C₂₇H₃₀ClNO₁₁ | 5 MG
Doxorubicin hydrochloride is a cytotoxic anthracycline antibiotic and an anti-cancer chemotherapy agent. It is a potent human DNA topoisomerase I and topoisomerase II inhibitor, reducing basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. It also induces apoptosis and autophagy.
- Potent human DNA topoisomerase I and topoisomerase II inhibitor
- Reduces basal phosphorylation of AMPK
- Induces apoptosis and autophagy
- Used in infection and cancer research
Alkali Scientific Doxorubicin Hydrochloride, Powder, 10 Mg
Doxorubicin Hydrochloride (powder form, 10 mg) is a chemotherapy drug used in the treatment of various cancers such as leukemia, breast cancer, and sarcomas. As a potent anthracycline antibiotic, it interferes with DNA replication and transcription by inserting itself between DNA base pairs, effectively halting cell division. This powder form allows for precise reconstitution, offering flexibility in clinical and research applications. Doxorubicin is crucial in cancer treatment protocols, often used in combination with other drugs to enhance therapeutic outcomes. Its cytotoxic action on cancer cells makes it one of the most widely utilized chemotherapeutic agents in oncological care.
Medchemexpress LLC BIIE-0246 | 246146-55-4 | 99.1% | 896.05 g·mol⁻¹ | C49H57N11O6 | 1 ML
BIIE-0246 is a potent, selective non-peptide antagonist of the neuropeptide Y Y2 receptor (NPY2R) used in preclinical neuroscience research. It has an IC50 of approximately 15 nM (rat [125I]PYY3-36) and modulates downstream signaling pathways including p-AKT and p44/42 MAPK. The compound is supplied as a 10 mM solution in DMSO with reported high purity for research use only.
- Potent NPY Y2 receptor antagonist (IC50 ~15 nM).
- Ready-to-use 10 mM solution in DMSO for in vitro assays.
- High reported purity (99.1%).
- Molecular weight 896.05 g·mol⁻¹ and formula C49H57N11O6.
- Suitable for studies of NPY2R signaling and related pathways.