Anthracyclines
Doxorubicin Hydrochloride 95.0+%, TCI America™
CAS: 25316-40-9 Molecular Formula: C27H30ClNO11 Molecular Weight (g/mol): 579.98 MDL Number: MFCD00077757,MFCD00077757,MFCD00941448 InChI Key: MWWSFMDVAYGXBV-FGBJBKNOSA-N Synonym: doxorubicin hydrochloride,adriamycin,doxorubicin hcl,adriacin,adriblastina,rubex,adriamycin hydrochloride,adriblastin,adriamycin pfs PubChem CID: 129626538 IUPAC Name: hydrogen (8S,10S)-10-[(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy]-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione chloride SMILES: [H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
Daunorubicin Hydrochloride 98.0+%, TCI America™
CAS: 23541-50-6 Molecular Formula: C27H30ClNO10 Molecular Weight (g/mol): 563.984 MDL Number: MFCD04974507 InChI Key: GUGHGUXZJWAIAS-QQYBVWGSSA-N Synonym: daunorubicin hydrochloride,daunorubicin hcl,daunomycin hydrochloride,daunoblastina,rubidomycin hydrochloride,daunorubicinol hydrochloride,daunoblastin,rubomycin,ondena,daunomycin chlorohydrate PubChem CID: 62770 IUPAC Name: (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride SMILES: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)C)O)N)O.Cl
Sigma Aldrich Fine Chemicals Biosciences Daunorubicin hydrochloride >=90% (HPLC) | 23541-50-6 | MFCD04974507 | 5MG
Daunorubicin hydrochloride >=90% (HPLC) | Purity: >=90% (HPLC) | Mol Wt: 563.98 | 23541-50-6 | MFCD04974507 | 5MG
Sigma Aldrich Fine Chemicals Biosciences Apoatropine hydrochloride10MG
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity water residual solvents inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH Co. KG
Medchemexpress LLC Doxorubicin-SMCC 10mM 1mL | 400647-59-8 | 1 ML
Doxorubicin-SMCC is a payload-linker conjugate that links the DNA topoisomerase II inhibitor doxorubicin to a non-cleavable SMCC linker for antibody-drug conjugate research. It is supplied as a 10 mM solution in DMSO.
- Ready-to-use 10 mM solution in DMSO, 1 mL.
- Non-cleavable SMCC linker for stable maleimide-thiol conjugation.
- Doxorubicin payload (topoisomerase II inhibitor) for potent cytotoxicity.
- High purity (98.8%) for reproducible conjugation and bioassays.
- Molecular weight 762.76 g·mol-1; formula C39H42N2O14.
- Storage: in solvent -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Doxorubicin (hydrochloride) | 25316-40-9 | C27H30ClNO11 | 25 MG
Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride; ADR) is a cytotoxic anthracycline antibiotic and an anti-cancer chemotherapy agent. It functions as a potent human DNA topoisomerase I and topoisomerase II inhibitor, reducing basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Additionally, it induces apoptosis and autophagy.
- Cytotoxic anthracycline antibiotic
- Anti-cancer chemotherapy agent
- Potent human DNA topoisomerase I and II inhibitor
- Reduces basal phosphorylation of AMPK and acetyl-CoA carboxylase
- Induces apoptosis and autophagy
- Suitable for neutral or weakly acidic solvents
- Melting/freezing point of 216°C
- For research use only
Medchemexpress LLC BIIE-0246 hydrochloride | 246146-55-4 | MFCD04113026 | >98.0% | 896.05 g/mol | C49H57N11O6 | 50 MG
BIIE-0246 is a selective, non-peptide antagonist of the neuropeptide Y Y2 receptor used as a research tool in receptor pharmacology and preclinical studies. It is typically supplied as the hydrochloride salt and is appropriate for in vitro assays and parenteral in vivo investigations.
- Selective antagonist of the NPY Y2 receptor.
- Potent activity (IC50 ≈ 15 nM).
- Typically supplied as a hydrochloride salt for lab use.
- Purity ≥98.0% by HPLC.
- Molecular weight 896.05 g/mol.
- Available in mg-scale quantities for research applications.
- Intended for research use only; not for human therapeutic use.
Medchemexpress LLC Doxorubicin (hydrochloride) | 25316-40-9 | C27H30ClNO11 | 100 MG
Doxorubicin hydrochloride (Standard) is an analytical standard and cytotoxic anthracycline antibiotic, primarily used as an anti-cancer chemotherapy agent. It functions as a potent human DNA topoisomerase I and topoisomerase II inhibitor, reducing basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase, while also inducing apoptosis and autophagy.
- Intended for research and analytical applications
- Functions as a cytotoxic anthracycline antibiotic
- Acts as an anti-cancer chemotherapy agent
- Potent human DNA topoisomerase I and II inhibitor
- Induces apoptosis and autophagy
- Used in qualitative and quantitative research experiments
- Suitable for HPLC, GC, and MS applications
Medchemexpress LLC BIIE-0246 hydrochloride | 99.1% | 896.05 g/mol | C49H57N11O6
BIIE-0246 hydrochloride is a potent, selective, non-peptide antagonist of the neuropeptide Y Y2 receptor (NPY2R) used in pharmacological and neuroscience research. Supplied as a white to off-white solid, the compound is offered as bulk material and as pre-made DMSO solutions for in vitro studies. Documentation such as COA, SDS, and analytical reports are available to support experimental reproducibility.
- Potent and selective NPY Y2 receptor antagonist for research applications.
- High purity (reported at 99.1%), reducing variability in assays.
- Available as solid material and as pre-made DMSO solutions for convenience.
- White to off-white solid appearance suitable for laboratory handling.
- Stability data provided for powder and solutions to aid storage planning.
- Analytical documentation (COA, HNMR, HPLC) available to verify quality.
Fisher Scientific Doxorubicin Hydrochloride, Fisher BioReagents
CAS: 25316-40-9 Molecular Formula: C27H30ClNO11 Molecular Weight (g/mol): 579.98 MDL Number: MFCD00077757,MFCD00077757,MFCD00941448 InChI Key: MWWSFMDVAYGXBV-FGBJBKNOSA-N Synonym: doxorubicin hydrochloride,adriamycin,doxorubicin hcl,adriacin,adriblastina,rubex,adriamycin hydrochloride,adriblastin,adriamycin pfs PubChem CID: 129626538 IUPAC Name: (7R,9R)-7-[(2S,4R,5R,6R)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride SMILES: [H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O