Cinnamic acids and derivatives
Electron Microscopy Sciences Oil Red O, Certified C.I. DcRo-3 10 GR
Oil Red O is lysochrome (fat soluble dye) used demonstrate fat or lipids in fresh tissue sections. The polyazo group of dyes include the Oil Red, Sudan Red and the Sudan Blacks - all these dyes are interchangeable. Also known as Solvent Red 27, Sudan Red 5B.
Cayman Chemical ANTIBODY AMG 9810 25mg
A derivative of the hallucinogen 2C-I with high affinity (Ki 0.049–0.21 nM) and activity (EC50 8.2 nM) at the serotonin receptor 5-HT2A intended for research and forensic applications
Cayman Chemical FerulIc AcId ethyl ester 5g
A selective inhibitor of ABHD6 (IC50 70 nM) increases Ucp1 expression and the OCR in differentiated 3T3-L1 mouse adipocytes at 10 UM increases the expression of Ucp1 Prdm16 Tmem26 and Tbx1 in visceral adipose tissue in mice fed a high-fat diet at 10 mg/kg per day reduces adipose tissue mass and prevents glucose-intolerance and increases in body weight in mice fed a high-fat diet increases brain levels of 2-AG and decreases EAE severity in wild-type but not CB2 receptor knockout mice at 10 mg/kg per day starting at disease onset
TARGETMOL CHEMICALS INC E/Z-DEMETHOXYCURCUMIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. (p-Hydroxycinnamoyl)feruloylmethane is found in Curcuma zedoaria and Etlingera elatior. It has a role as a metabolite an antineoplastic agent and an anti-inflammatory agent. purity: 98%
TARGETMOL CHEMICALS INC TYRPHOSTIN AG 538 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Tyrphostin AG 538 is a chalcone compound an IGF-1 receptor kinase inhibitor (IC₅0 for 400 nM) that is potent cell-permeable reversible and competitive. purity: 99%
TARGETMOL CHEMICALS INC BISDEMETHOXYCURCUMIN 50MG
Also available in 5 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Bisdemethoxycurcumin (Curcumin III) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis interacting with 1(alpha) 25-dihydroxy vitamin D3 to stimulate amyloid-(beta) clearance by macrophages (optimal stimulation at 100 nM BDMC) [1]. More stable than curcumin in physiological media BDMC suppresses proliferation of cancer cells [2]. It down-regulates the transcriptional coactivator p300 suppressing the Wnt/(beta)-catenin pathway and inhibits LPS induction of iNOS expression [3]. purity: 99%
Accela Chembio Inc 2-methylcinnamic Acid | Predominantly Trans | 25g | 2373-76-4 | MFCD00016841 | 97+% | Shelf Life: 1260 Days | Light Sensitive
2-methylcinnamic Acid | Predominantly Trans | 25g | 2373-76-4 | MFCD00016841 | 97+% | Shelf Life: 1260 Days | Light Sensitive
Cayman Chemical CurcumIn-d6 500ug
An antibiotic that has activity against Gram-positive bacteria via inhibition of WalR (MICs 0.39 and 3.13 g/ml for B. subtilis and S. aureus respectively) inhibits WalR-induced repression of EGFP signaling in a reporter assay in a concentration-dependent manner alters expression of WalR regulon genes decreasing ydjM yocH and ycvE and increasing yoeB and yjeA expression in B. subtilis halts transcription of isaA and ssaA in S. aureus
Cayman Chemical FerulIc AcId 50g
A B1 adrenergic receptor antagonist and a B2 adrenergic receptor partial agonist that relaxes human arteries and veins with ED50 values of 40-50 UM in vitro reduces myocardial infarct size and increases NO production in a rabbit model of myocardial ischemia at 1-10 mg/kg/h
Cayman Chemical FerulIc AcId 25g
A potent inhibitor of JAK2 that also inhibits the JAK2V617F mutant enzyme (IC50s for both enzymes 0 5 nM) orally bioavailable with a long half-life in vivo suppressing leukemic cell spreading and splenomegaly in JAK2V617F cell-driven disease in mice
Selleck Chemical LLC Tyrphostin 9 S2895-25mg
Tyrphostin 9 (SF 6847 RG-50872) is firstly designed as an EGFR inhibitor with IC50 of 460 M but is also found to be more potent to PDGFR with IC50 of 0 5 M
Accela Chembio Inc 4-hydroxy-3 | 5-dimethoxycinnamic Acid | Predominantly Trans | 5g | 530-59-6 | MFCD00004401 | 97+% | Shelf Life: 1080 Days | Light Sensitive
4-hydroxy-3 | 5-dimethoxycinnamic Acid | Predominantly Trans | 5g | 530-59-6 | MFCD00004401 | 97+% | Shelf Life: 1080 Days | Light Sensitive
Selleck Chemical LLC p-Coumaric Acid S4759-25mg
p-Coumaric acid (4-Hydroxycinnamic acid P-Hydroxycinnamic acid 4-Coumaric acid Trans-p-Coumaric acid para-Coumaric Acid) is a hydroxy derivative of cinnamic acid found in a variety of edible plants and is reported to have antioxidant anti-inflammatory and antimicrobial activity
Selleck Chemical LLC Bisdemethoxycurcumin (BDMC) S3938-25mg
Bisdemethoxycurcumin (BDMC) is a natural demethoxy derivative of curcumin and possesses several biological activities such as anti-inflammation and anti-cancer activities