Cinnamic acids and derivatives
Sigma Aldrich Fine Chemicals Biosciences 4-Formylcinnamic acid, predominantly trans | 23359-08-2 | MFCD00006955 | 5G
4-Formylcinnamic acid, predominantly trans | Mol Wt: 176.17 | 23359-08-2 | MFCD00006955 | 5G
Medchemexpress LLC p-Coumaric acid (Standard) | 501-98-4 | 164.16 | 50 MG
p-Coumaric acid (Standard) is the analytical standard of p-Coumaric acid, intended for research and analytical applications. It is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation and promotes apoptosis. It also has antibacterial, anti-inflammatory, antioxidant, and anti-tumor activities.
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
- Exhibits antibacterial activity
- Exhibits anti-inflammatory activity
- Exhibits antioxidant activity
- Exhibits anti-tumor activity
Medchemexpress LLC p-Coumaric Acid Ethyl Ester | 7362-39-2 | 100 MG
p-Coumaric Acid Ethyl Ester is a non-competitive, reversible inhibitor of tyrosinase, used in the development of medicines, cosmetics, and fruit preservation products derived from pollen. It functions by quenching the intrinsic fluorescence of the enzyme and inducing conformational changes in the catalytic domain of tyrosinase, which alters the binding affinity of L-tyrosine without binding to the copper ion.
- Tyrosinase inhibition: Non-competitive, reversible inhibitor with IC50 = 4.89 μg/mL and Ki = 1.83 μg/mL
- Shows anti-platelet activity in rabbit platelet-rich plasma (IC50 = 130.4 μM)
- Used in the development of medicines, cosmetics, and fruit preservation products
- High purity of 99.19%
- Molecular weight: 192.21
- Chemical formula: C11H12O3
- Appearance: Solid, light yellow to light brown
- Soluble in DMSO at 100 mg/mL (520.26 mM)
Medchemexpress LLC Ferulic acid 4-O-sulfate | 86321-29-1 | 98.1% | 274.25 | 25 MG
Ferulic acid 4-O-sulfate, also known as Ferulic acid 4-sulfate, is a significant metabolite of Ferulic acid. This compound has demonstrated a notable ability to relax arteries and reduce blood pressure in mice, indicating its potential role in cardiovascular research. Its in vitro studies show concentration-dependent relaxations in various mouse arteries, while in vivo applications have resulted in a decrease in mean arterial pressure.
- Relaxes arteries and lowers blood pressure
- Demonstrates concentration-dependent relaxations in mouse arteries
- Significantly decreases mean arterial pressure in vivo
- Intended for research and analytical applications
eMolecules 2-Fluorocinnamic acid | 451-69-4 | MFCD00004370 | 25g
Matrix Scientific | 2-Fluorocinnamic acid | 25g | 389714243 | 4179 | 98.000 | 451-69-4 | MFCD00004370 | 166.151 | C9H7FO2
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Medchemexpress LLC Cinnamic acid | 621-82-9 | MFCD00004369 | 148.16 | 1 G
Cinnamic acid has potential use in cancer intervention, exhibiting IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate, and lung carcinoma cells. In addition to inhibiting tumor-cell proliferation, Cinnamic acid induces morphological changes consistent with melanocyte differentiation. Treatment with Cinnamic acid also leads to a dose-dependent loss of invasive capacity in various tumor lines.
- Endogenous metabolite
- Potential use in cancer intervention
- Exhibits dose-dependent growth inhibition in various tumor cells
- Induces morphological changes consistent with melanocyte differentiation
- Causes dose-dependent loss of invasive capacity in tumor lines
- Purity: 99.98%
- Appearance: Solid
- Color: White to off-white
- Initial source: Microorganisms
- Storage: powder at -20°C for 3 years, 4°C for 2 years; in solvent at -80°C for 2 years, -20°C for 1 year
Chem-Impex International, Inc. trans-Ferulic acid | 1135-24-6 | MFCD00004400 | 25G
trans-Ferulic acid, 1135-24-6, MFCD00004400, 25G
Medchemexpress LLC p-Coumaric acid (standard) | 501-98-4 | 164.16 | 100 MG
p-Coumaric acid (Standard) is the analytical standard of p-Coumaric acid, intended for research and analytical applications. It is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation, promotes apoptosis, and exhibits antibacterial, anti-inflammatory, antioxidant, and anti-tumor activities.
- Analytical standard for research and analytical applications
- Inhibits cell proliferation and promotes apoptosis
- Exhibits antibacterial, anti-inflammatory, antioxidant, and anti-tumor activities
- Used as a reference standard in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Chem-Impex International, Inc. trans-Ferulic acid | 1135-24-6 | MFCD00004400 | 250G
trans-Ferulic acid, 1135-24-6, MFCD00004400, 250G
Medchemexpress LLC p-Coumaric acid ethyl ester | 7362-39-2 | MFCD00210460 | 50 MG
p-Coumaric Acid Ethyl Ester is a non-competitive, reversible inhibitor of tyrosinase. It quenches the intrinsic fluorescence of the enzyme and changes the binding affinity of L-tyrosine by inducing conformational changes in the catalytic domain of tyrosinase, without binding to the copper ion of the enzyme. This compound is utilized in the development of medicines, cosmetics, and for fruit preservation.
- Non-competitive, reversible inhibitor of tyrosinase
- Quenches the intrinsic fluorescence of the enzyme
- Induces conformational changes in the catalytic domain of tyrosinase without binding to copper ion
- Exhibits anti-platelet activity in rabbit platelet-rich plasma
- Utilized in medicine and cosmetic development
- Used for fruit preservation
Selleck Chemical LLC p-Coumaric Acid S4759-25mg
p-Coumaric acid (4-Hydroxycinnamic acid P-Hydroxycinnamic acid 4-Coumaric acid Trans-p-Coumaric acid para-Coumaric Acid) is a hydroxy derivative of cinnamic acid found in a variety of edible plants and is reported to have antioxidant anti-inflammatory and antimicrobial activity
Medchemexpress LLC α-cyano-4-hydroxycinnamic acid | 28166-41-8 | MFCD00004204 | 99.9% | 189.17 g·mol⁻¹ | C10H7NO3 | 100 MG
α-Cyano-4-hydroxycinnamic acid is a cinnamic acid derivative used as a research reagent and biochemical tool. It acts as a potent, non-competitive inhibitor of monocarboxylate transporters (MCTs) and is commonly used as a matrix in MALDI mass spectrometry and in studies of lactate transport and metabolism.
- Potent non-competitive inhibitor of monocarboxylate transporters.
- Suitable as a MALDI matrix for peptide analysis.
- High purity, 99.9% (reported 99.92%).
- Molecular weight 189.17 g·mol⁻¹.
- Supplied as a solid for laboratory use.
Medchemexpress LLC 4-Methoxycinnamic acid | 830-09-1 | 178.19 | 100 G
4-Methoxycinnamic acid is recognized as a natural phenylpropanoid found in A. preissii. It is used for research purposes only and is not sold to patients.
- Detected as natural phenylpropanoid in A. preissii.
- For research use only.
- Purity: 99.87%.
- Appears as a solid with an off-white to light yellow color.
- Initial source is an endogenous metabolite.
Medchemexpress LLC p-Coumaric Acid Ethyl Ester | 7362-39-2 | 1 ML
p-Coumaric Acid Ethyl Ester, also known as Ethyl (E)-p-hydroxycinnamate or Ethyl trans-4-hydroxycinnamate, is a reversible, non-competitive inhibitor of tyrosinase. It quenches the enzyme's intrinsic fluorescence and alters the binding affinity of L-tyrosine by inducing conformational changes in the catalytic domain, without binding to the copper ion. This compound finds application in the development of various products, including medicines, cosmetics, and fruit preservation products that utilize pollen.
- Non-competitive and reversible tyrosinase inhibitor.
- Changes L-tyrosine binding affinity through conformational changes in tyrosinase's catalytic domain.
- Does not bind to the copper ion of the enzyme.
- Applicable in developing medicines.
- Used in cosmetic formulations.
- Utilized in fruit preservation products.