Coumarins and derivatives
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | 50 G
4-Hydroxycoumarin is an orally active coumarin derivative, a versatile heterocyclic scaffold used in synthesizing various organic compounds. It possesses both electrophilic and nucleophilic properties. It acts as an HIV protease inhibitor and tyrosine kinase inhibitor, and exhibits anti-inflammatory, antibacterial, and anti-tumor effects.
- Orally active coumarin derivative
- Versatile heterocyclic scaffold for organic compound synthesis
- Possesses both electrophilic and nucleophilic properties
- Acts as an HIV protease inhibitor
- Acts as a tyrosine kinase inhibitor
- Exhibits anti-inflammatory effects
- Exhibits antibacterial effects
- Exhibits anti-tumor effects
Indofine Chemical 7-Hydroxycoumarin, 99%, 5 Gm
7-HYDROXYCOUMARIN 5 GM, Coumarin, Umbelliferone, C9H6O3, MW: 162.14, 99+%, 93-35-6, MFCD00006878
Selleck Chemical LLC Dicoumarol-50mg
Dicoumarol is a competitive NADPH quinone oxidoreductase (NQO1) inhibitor,and used as an anticoagulant by interfering with the metabolism of vitamin K.
Sigma Aldrich Fine Chemicals Biosciences 7-Methoxycoumarin >=98% | 531-59-9 | MFCD00006876 | 25G
7-Methoxycoumarin >=98% | Purity: >=98% | Mol Wt: 176.17 | 531-59-9 | MFCD00006876 | 25G
Medchemexpress LLC Linarin (buddleoside) | 480-36-4 | MFCD00151178 | 98.0% | 592.55 | C28H32O14 | 10 MG
Linarin (buddleoside) is a naturally occurring flavonoid glycoside and an orally active, selective acetylcholinesterase (AChE) inhibitor. It has reported anti-inflammatory, antioxidant, sedative, bone differentiation, antitumor, antibacterial, and antiviral activities and is used in research on nervous system disorders, osteoporosis, and cancer.
- Natural flavonoid glycoside, also known as buddleoside.
- Selective acetylcholinesterase (AChE) inhibitor, orally active.
- CAS 480-36-4; formula C28H32O14; molecular weight 592.55.
- Purity typically 98.0% as supplied.
- White to off-white solid; soluble in DMSO (≈250 mg/mL).
- Storage: protect from light; short-term 4°C; in solution -20°C to -80°C as specified.
- Supplied in small research quantities suitable for in vitro and in vivo studies.
Medchemexpress LLC My-1076 | 3008262-76-5 | MFCD35444266 | 99.1% | 539.57 g·mol-1 | C29H33NO9 | 10 MG
MY-1076 is a small-molecule inhibitor of Yes-associated protein (YAP) used for laboratory research. It induces YAP degradation and apoptosis and shows potent antiproliferative activity against several cancer cell lines with low-nanomolar IC50s. Reported properties include CAS 3008262-76-5, formula C29H33NO9, molecular weight 539.57 g·mol-1, and high reported purity.
- Induces YAP degradation and apoptosis in vitro
- Potent antiproliferative activity with low-nanomolar IC50s
- High purity suitable for analytical and biological studies
- Available in multiple small-scale quantities for research use
- Intended for research use only; not for human or clinical use
Medchemexpress LLC 6-Hydroxycoumarin | 6093-68-1 | 1 G
6-Hydroxycoumarin is a coumarin with a broad spectrum of biological activities, including anti-inflammatory, anti-pyretic, anti-oxidant, vasodilator, anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic, and antitumor properties. It has shown cytotoxicity against various human cancer cell lines such as COLO 205, HCT-116, HL-60, SK-MEL-28, and SK-MEL3.
- Exhibits anti-inflammatory, anti-pyretic, and anti-oxidant effects
- Functions as a vasodilator
- Displays anti-amoebic, anti-bacterial, anti-fungal, and bacteriostatic activities
- Possesses antitumor activity
- Demonstrates cytotoxicity against multiple human cancer cell lines
- Intended for research use only
Medchemexpress LLC 7-Methylcoumarin | 2445-83-2 | MFCD00006880 | 5 G
7-Methylcoumarin is a coumarin derivative known for its potent hepatoprotective and antioxidant properties. It functions as a mechanism-based inhibitor for CYP2A6, a key enzyme involved in drug metabolism. Studies have shown that it can significantly reduce markers of liver damage, such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB), in models of CCl4-induced liver injury. Additionally, it helps to restore total protein (TP) and albumin (TA) levels and prevent oxidative stress. It also exhibits an ability to decrease the mitotic activity of *A. sativum* promeristem.
- Possesses potent hepatoprotective properties
- Acts as a mechanism-based inhibitor for CYP2A6
- Reduces markers of liver damage
- Restores protein and albumin levels in serum
- Prevents oxidative stress
- Decreases mitotic activity
Medchemexpress LLC Coumarin 6 | 38215-36-0 | 1 ML
Coumarin 6 is a fluorescent dye utilized as a fluorescent probe within microparticle drug delivery systems. It is employed to conduct in vivo tracking, cellular uptake studies, and investigations into the transport mechanisms of drug delivery systems. It has an excitation wavelength (λexc) of 450 nm and an emission wavelength (λem) of 505 nm. This product is intended for research use only and is not sold to patients.
- Used for in vivo tracking, cell uptake, and transport mechanism studies in drug delivery systems
- Optimal wavelengths: Excitation at 450 nm and emission at 505 nm
- Purity: 99.59%
Medchemexpress LLC 4-Hydroxycoumarin (standard) | 1076-38-6 | 50 MG
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin, intended for research and analytical applications. It is an orally active coumarin derivative and a versatile heterocyclic scaffold, frequently used in the synthesis of diverse organic compounds. The product exhibits both electrophilic and nucleophilic properties.
- Analytical standard.
- Intended for research and analytical applications.
- Orally active coumarin derivative.
- Versatile heterocyclic scaffold.
- Used in the synthesis of various organic compounds.
- Possesses both electrophilic and nucleophilic properties.
- Functions as an HIV protease inhibitor.
- Functions as a tyrosine kinase inhibitor.
- Displays anti-inflammatory effects.
- Displays antibacterial effects.
- Displays anti-tumor effects.