Flavonoids
Medchemexpress LLC Kaempferol 3-O-rutinoside 7-O-glucoside | 34336-18-0 | 5 MG
Kaempferol 3-O-rutinoside 7-O-glucoside is a flavonoid glycoside found in red tomato, as well as organisms such as Crocus minimus and Crocus chrysanthus. It is intended for research use only.
- Purity: 99.67%
- Molecular formula: C33H40O20
- Molecular weight: 756.66
- Appearance: Off-white to light yellow solid
- Classified as a flavonoid, flavonol, phenol, and polyphenol
Medchemexpress LLC Gallocatechin gallate | 5127-64-0 | 1 MG
Gallocatechin gallate is a flavonoids product that can be isolated from the herbs of Celastrus orbiculatus. It is intended for research use only.
- Molecular weight: 458.37
- Formula: C22H18O11
- Appearance: Solid
- Color: White to off-white
- Purity: 98%
- Storage: -20°C, sealed storage, away from moisture and light. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light).
- Structure classification: Flavonoids
- Initial source: Plants, celastraceae, celastrus, Celastrus orbiculatus Thunb.
Selleck Chemical LLC Farrerol-5mg
Farrerol, an important bioactive constituent of rhododendron, exhibits broad activities such as anti-oxidative and anti-inflammatory effects.
Apexbio Technology LLC AST 487 630124-46-8 10mM (in 1mL DMSO)
AST487 (CAS 630124-46-8) is a small molecule inhibitor primarily targeting RET kinase exhibiting an IC50 of 0 88 M As a member of the N N -diphenylurea class AST487 inhibits RET autophosphorylation and attenuates downstream signaling pathways such as PLC and ERK in a dose-dependent manner It also displays inhibitory activity against additional kinases including KDR Flt-3 and c-Kit In cellular models harboring RET activating mutations (e g C634W) AST487 suppresses RET-mediated signaling and reduces proliferation of thyroid carcinoma cells with RET mutations In xenograft mouse models oral administration of AST487 leads to a notable reduction in tumor volume making it valuable for preclinical studies of RET-driven cancers
Selleck Chemical LLC AMG 487
AMG 487 is an orally active and selective CXC chemokine receptor 3 (CXCR3) antagonist that inhibits the binding of IP-10 (CXCL10) and ITAC (CXCL11) to CXCR3 with IC50 of 8 0 nM and 8 2 nM respectively
Medchemexpress LLC Myricetin | 529-44-2 | C15H10O8 | 200 MG
Myricetin is a plant-derived flavonoid known for its strong antioxidant, anticancer, antidiabetic, and anti-inflammatory properties. It exhibits diverse cellular effects, including radical scavenging activity and the ability to modulate various signaling pathways, making it suitable for a wide range of research applications.
- Exhibits scavenging activity against various radicals and ions.
- Prevents cancer cell death by apoptosis through regulation of PI3K/Akt and MAPK signaling pathways.
- Displays antiphotoaging effects by quenching free radicals in the skin and suppressing UVB-induced COX-2 expression.
- Inhibits human Hsp70 with notable IC50 values.
- Causes inhibition of rabbit platelet aggregation induced by ADP, arachidonic acid, collagen, and PAF.
Medchemexpress LLC 3-Hydroxy-7-methoxyflavone | 7478-60-6 | 99.4% | 268.26 | 5 MG
3-Hydroxy-7-methoxyflavone is a flavonoid isolated from natural Salvia elegans, known for its anti-anxiety effects. This compound is for research use only.
- Isolated from natural Salvia elegans.
- Exhibits anti-anxiety effects.
- Cytotoxicity against human KB cells with an ED50 of 26 µg/mL.
- Recommended storage at room temperature for 3 years, or in solvent at -80°C for 2 years or -20°C for 1 year.
- Soluble in DMSO at 50 mg/mL.
Medchemexpress LLC Methyl-Hesperidin | 11013-97-1 | MFCD01741310 | 98.3% | 624.59 | 50 MG
Methyl-Hesperidin is a vasodilating agent. It is for research use only and not sold to patients.
- Appearance: Solid
- Color: White to light yellow
- Structure classification: Flavonoids, flavonones, phenols, polyphenols
- Initial source: Plants, other families
- Storage: 4°C, protect from light. In solvent: -80°C for 6 months; -20°C for 1 month (protect from light)
- Purity: 98.29%
- Molecular weight: 624.59
- CAS number: 11013-97-1
TARGETMOL CHEMICALS INC Apigenin 200MG
Also available in 1 g, 1 mL, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Apigenin (NSC 83244) is an aromatic oil extracted from the flowers or leaves of the daisy-like plants. Extracts, oils and teas made from chamomile are used for its soothing qualities as a sedative, mild analgesic and sleep medication. Apigenin has not been implicated in causing serum enzyme elevations or clinically apparent liver injury. Purity 99.66%
Selleck Chemical LLC AST-487
AST-487 (NVP-AST487) a N N -diphenyl urea is an ATP competitive inhibitor of Flt3 with ki of 0 12 M Besides FLT3 AST487 also inhibits RET KDR c-KIT and c-ABL kinase with IC50 values below 1 M