Isoflavonoids
Medchemexpress LLC 5-Methyl-7-methoxyisoflavone | 82517-12-2 | 266.29 | 25 MG
5-Methyl-7-methoxyisoflavone is an orally active antioxidant with remyelinating activity. It inhibits the enzyme aromatase, interfering with the normal metabolic pathways of testosterone. It is a non-steroidal anabolic isoflavone used as an anabolic agent, showing better potency in increasing muscle mass and endurance. This compound can also be used for fat loss, maintaining low cholesterol levels, and strengthening bones. Additionally, 5-Methyl-7-methoxyisoflavone acts as an inhibitor for NF-κB.
- Orally active antioxidant with remyelinating activity.
- Inhibits aromatase enzyme.
- Non-steroidal anabolic isoflavone, acts as an anabolic agent.
- Increases muscle mass and endurance.
- Aids in fat loss.
- Helps maintain low cholesterol levels.
- Strengthens bones.
- Inhibitor for NF-κB.
- Inhibits the clonogenicity of HCT116 colon cancer cells in vitro.
Medchemexpress LLC Sophoricoside | 152-95-4 | 432.38 | 50 MG
Sophoricoside is an isoflavone glycoside isolated from *Sophora japonica*. It exhibits anti-inflammatory, anti-cancer, and immunosuppressive effects. It is intended for research use only and not for sale to patients.
- Anti-inflammatory effects
- Anti-cancer effects
- Immunosuppressive effects
Medchemexpress LLC Genistin | 529-59-9 | 432.38 | 100 MG
Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of the ERalpha signaling pathway.
- An isoflavone belonging to the phytoestrogen family.
- Potent anti-adipogenic and anti-lipogenic agent.
- Attenuates cellular growth.
- Promotes apoptotic cell death in breast cancer cells through modulation of the ERalpha signaling pathway.
Medchemexpress LLC Genistein 8-c-glucoside | 66026-80-0 | 1 ML
Genistein 8-c-glucoside (G8CG) is a glucoside for research use only that induces mitochondrial membrane depolarization and apoptosis.
- Induces mitochondrial membrane depolarization
- Induces apoptosis
- For research use only
Medchemexpress LLC Formononetin | 485-72-3 | 98.79% | 268.26 | 5 MG
Formononetin (Standard) is the analytical standard of Formononetin, intended for research and analytical applications. It is a potent FGFR2 inhibitor that potently inhibits angiogenesis and tumor growth. The compound is of analytical standard grade, used as a reference standard in qualitative, quantitative, and methodological research experiments.
- Analytical standard of Formononetin
- Potent FGFR2 inhibitor with an IC50 of ~4.31 μM
- Potently inhibits angiogenesis and tumor growth
- Commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS
Medchemexpress LLC Daidzein-4',7-diglucoside | 53681-67-7 | 99.7% | 578.52 | 5 MG
Daidzein-4',7-diglucoside is a natural product that can be isolated from *Radix puerariae*. It is intended for research use only.
- Isolated from *Radix puerariae*
- Appears as a solid
- Color is white to off-white
- Classified as a flavonoid and isoflavone
- Initial source is plants, Leguminosae, *Piptanthus nepalensis (Hook.) D. Don*
- Part of compound screening libraries
- Cited in one publication
Apexbio Technology LLC Puerarin 3681-99-0 50mg
Puerarin (CAS 3681-99-0) is an isoflavone compound isolated from the root of Pueraria lobata It exerts multiple pharmacological effects primarily through modulation of oxidative stress and inflammatory signaling pathways Puerarin has been reported to enhance myocardial perfusion protect against ischemic injury and regulate glucose and lipid metabolism in preclinical models Additionally it demonstrates neuroprotective properties including mitigation of neuronal damage associated with neurodegenerative conditions Puerarin is widely studied for its potential in cardiovascular metabolic and neurological disease research
Apexbio Technology LLC Genistein(Synonyms: 4',5,7-Trihydroxyisoflavone, Genisteol, Prunetol, Sophoricol, Differenol A), 100mg, CAS: 446-72-0.
Genistein (CAS 446-72-0) is an isoflavonoid compound that selectively inhibits protein tyrosine kinases enzymes implicated in signaling pathways associated with oncogenic activity and cellular proliferation Genistein inhibits tyrosine kinase activity with an IC50 of approximately 8 M In NIH-3T3 cell assays genistein suppresses epidermal growth factor (EGF)-mediated mitogenesis (IC50 12 M) and insulin-mediated effects (IC50 19 M) additionally inhibiting EGF-induced activation of S6 kinase at a concentration of 6 15 M In animal models oral administration of genistein demonstrates dose-dependent inhibition of prostate adenocarcinoma development highlighting its utility in cancer biology research and potential chemopreventive applications
Apexbio Technology LLC Daidzein 486-66-8 1g
Daidzein is an isoflavone compound derived from soybeans structurally classified as a phytoestrogen with structural similarity to endogenous estrogen It has been widely investigated for its potential in biomedical research particularly in oncology and cell biology studies Daidzein exhibits anticancer-related biological activity possibly via modulation of hormonal signaling pathways and interference with cell cycle progression as exemplified by inducing cell cycle arrest at the G1 phase in cultured mammalian cells Additionally it demonstrates antioxidant properties providing protective effects against oxidative stress-mediated cell injury such as hepatic cellular damage induced by chemical carcinogens Daidzein is thus employed in studies focused on hormone-dependent tumorigenesis cell-cycle regulation mechanisms and oxidative-stress-induced cellular responses
Apexbio Technology LLC Genistein(Synonyms: 4',5,7-Trihydroxyisoflavone, Genisteol, Prunetol, Sophoricol, Differenol A), 10mM (in 1mL DMSO), CAS: 446-72-0.
Genistein (CAS 446-72-0) is an isoflavonoid compound that selectively inhibits protein tyrosine kinases enzymes implicated in signaling pathways associated with oncogenic activity and cellular proliferation Genistein inhibits tyrosine kinase activity with an IC50 of approximately 8 M In NIH-3T3 cell assays genistein suppresses epidermal growth factor (EGF)-mediated mitogenesis (IC50 12 M) and insulin-mediated effects (IC50 19 M) additionally inhibiting EGF-induced activation of S6 kinase at a concentration of 6 15 M In animal models oral administration of genistein demonstrates dose-dependent inhibition of prostate adenocarcinoma development highlighting its utility in cancer biology research and potential chemopreventive applications