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Compounds that are analog of macrolides that contain lactam rings in place of lactone rings; they are a class of antibiotics. Lactam rings are nitrogen analogs of lactone rings.
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MW 804 Da, Purity >98%. Immunosuppressant. Complexes with FKBP-12 to inhibit calcineurin. Achieve your results faster with highly validated, pure and trusted compounds.
MW 804 Da, Purity >98%. Immunosuppressant. Complexes with FKBP-12 to inhibit calcineurin. Achieve your results faster with highly validated, pure and trusted compounds.
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LL-37 FK-13 TFA is the TFA salt form of LL-37 FK-13 (HY-P4836). It is an antimicrobial agent that inhibits *Trichomonas vaginalis*. LL-37 FK-13 TFA shows minimal hemolytic effects on human erythrocytes and low cytotoxicity to human fibroblasts.
Antimicrobial agent
Inhibits *Trichomonas vaginalis*
Minimal hemolytic effects on human erythrocytes
Low cytotoxicity to human fibroblasts
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LL-37 FK-13 TFA is the TFA salt form of LL-37 FK-13. It functions as an antimicrobial agent that inhibits *Trichomonas vaginalis*. This compound demonstrates minimal hemolytic effects on human erythrocytes and low cytotoxicity to human fibroblasts.
TFA salt form of LL-37 FK-13
Functions as an antimicrobial agent
Inhibits *Trichomonas vaginalis*
Demonstrates minimal hemolytic effects on human erythrocytes
Exhibits low cytotoxicity to human fibroblasts
Appears as a solid, white to off-white in color
Soluble in H2O at ≥ 100 mg/mL
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Tacrolimus monohydrate (FK506 monohydrate) is a macrocyclic lactone. It binds to FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. It possesses immunosuppressive properties and is intended for research use only.
Inhibits calcium-dependent events like IL-2 gene transcription, NO synthase activation, cell degranulation, and apoptosis.
Potentiates actions of glucocorticoids and progesterone by binding to FKBPs.
May enhance expression of the TGFβ-1 gene.
Inhibits T cell proliferation in response to T cell receptor ligation.
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