Transition Metals

Medchemexpress LLC (3R)-N,N-dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyrrolidin-3-amine | 2089389-15-9 | 99.8% | 307.39 g/mol | C18H21N5 | 1 ML

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(R)-ZINC-3573 is a small-molecule probe and selective agonist of the Mas-related G protein-coupled receptor X2 (MRGPRX2), supplied for research use. It is provided as a ready-to-use 10 mM solution in DMSO (1 mL) and is also available as solid quantities for assay development and pharmacology studies.

• Selective MRGPRX2 agonist for pain and itch research.
• Supplied as 10 mM solution in DMSO, 1 mL volume.
• High purity suitable for biochemical and cellular assays.
• Chemical formula C18H21N5; molecular weight 307.39 g/mol.
• For research use only; not for human or diagnostic use.

Apexbio Technology LLC Vortioxetine (Lu AA21004) HBr 960203-27-4 10mM (in 1mL DMSO)

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Vortioxetine (Lu AA21004) HBr (CAS 960203-27-4) is a multimodal antidepressant that modulates the serotonergic system It acts as an antagonist at the human 5-HT3A (Ki 3 7 nM) and 5-HT7 receptors (Ki 19 nM) a partial agonist at the 5-HT1B receptor (Ki 33 nM EC50 460 nM) an agonist at 5-HT1A (Ki 15 nM) and inhibits the serotonin transporter (hSERT Ki 1 6 nM) In cellular assays it demonstrates functional antagonism at 5-HT7 and partial agonism at 5-HT1B In vivo vortioxetine modulates serotonergic activity in rodents with ED50 values of 0 4 mg/kg for rSERT and 0 11 mg/kg for 5-HT3 It is utilized in neuropharmacological studies to investigate serotonergic signaling and depression-related mechanisms

Apexbio Technology LLC Vortioxetine (Lu AA21004) HBr 960203-27-4 25mg

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Vortioxetine (Lu AA21004) HBr (CAS 960203-27-4) is a multimodal antidepressant that modulates the serotonergic system It acts as an antagonist at the human 5-HT3A (Ki 3 7 nM) and 5-HT7 receptors (Ki 19 nM) a partial agonist at the 5-HT1B receptor (Ki 33 nM EC50 460 nM) an agonist at 5-HT1A (Ki 15 nM) and inhibits the serotonin transporter (hSERT Ki 1 6 nM) In cellular assays it demonstrates functional antagonism at 5-HT7 and partial agonism at 5-HT1B In vivo vortioxetine modulates serotonergic activity in rodents with ED50 values of 0 4 mg/kg for rSERT and 0 11 mg/kg for 5-HT3 It is utilized in neuropharmacological studies to investigate serotonergic signaling and depression-related mechanisms

Apexbio Technology LLC Vortioxetine (Lu AA21004) HBr 960203-27-4 100mg

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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Vortioxetine (Lu AA21004) HBr (CAS 960203-27-4) is a multimodal antidepressant that modulates the serotonergic system It acts as an antagonist at the human 5-HT3A (Ki 3 7 nM) and 5-HT7 receptors (Ki 19 nM) a partial agonist at the 5-HT1B receptor (Ki 33 nM EC50 460 nM) an agonist at 5-HT1A (Ki 15 nM) and inhibits the serotonin transporter (hSERT Ki 1 6 nM) In cellular assays it demonstrates functional antagonism at 5-HT7 and partial agonism at 5-HT1B In vivo vortioxetine modulates serotonergic activity in rodents with ED50 values of 0 4 mg/kg for rSERT and 0 11 mg/kg for 5-HT3 It is utilized in neuropharmacological studies to investigate serotonergic signaling and depression-related mechanisms

STA PHARMACEUTICAL US LLC 2'-TOM MeC(Ac) amidite | 1 g | CAS 872548-65-7 | InChIKey OBHVHGNMPRNNPM-RNGKMJNNSA-N

2'-TOM MeC(Ac) amidite is a Amidite reagent (Subcategory: 2'-OH Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. Ships on dry ice. SDS available for reference.

Specifications
- CAS: 872548-65-7
- MDL: No data
- InChIKey: OBHVHGNMPRNNPM-RNGKMJNNSA-N
- Molecular Weight: 988.247761998
- Molecular Formula: C52H74N5O10PSi
- Purity: ≥95%
- Container Type: 15 mL HDPE
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 7.8 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-5-(4-acetamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((triisopropylsilyl)oxy)methoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@@H]1[C@H](O[C@@H](N2C=C(C(NC(C)=O)=NC2=O)C)[C@@H]1OCO[Si](C(C)C)(C(C)C)C(C)C)COC(C3=CC=C(C=C3)OC)(C4=CC=C(C=C4)OC)C5=CC=CC=C5)OCCC#N)C(C)C)C