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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
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p-SCN-Bn-DOTA is a bifunctional chelating agent that combines an isothiocyanate reactive group for covalent protein conjugation with a DOTA macrocycle for stable radiometal chelation. It is used to conjugate radionuclides to antibodies and other biomolecules for radioimaging and radioimmunotherapy applications.
Bifunctional chelator with an isothiocyanate reactive group for protein conjugation.
DOTA macrocycle enables stable chelation of radiometals.
Suitable for antibody conjugation and radioimmunoassays.
Available as a solid powder, typically supplied in milligram-scale quantities.
High purity suitable for research applications.
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Mouse CD137 mRNA encodes CD137P(4-1BB) mainly expressed on activated T cells natural killer (NK) cells and dendritic cells The ligand for CD137 is 4-1BBL primarily expressed on antigen-presenting cells Activation of CD137 enhances T-cell proliferation and survival and promotes the secretion of cytokines such as IFN- and IL-2 thereby strengthening immune responses Activating CD137 can enhance anti-tumor immune responses CD137 signaling pathways play complex roles in autoimmune diseases and transplant rejection EZ Cap Mouse CD137 mRNA (m1 HA tag) supplied at 1 mg/mL encodes mouse-derived CD137 cytokine fused to HA tag facilitating subsequent protein expression detection It contains a cap 1 structure generated through co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
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RS100329 hydrochloride is a selective α1A-adrenoceptor antagonist supplied as the hydrochloride salt for research use. It is reported to have high affinity for α1A (pKi ≈ 9.6) with lower affinity for α1D and α1B, and is used in preclinical studies including investigations of urethral reflex contractions and benign prostatic hyperplasia.
Selective α1A-adrenoceptor antagonist for receptor pharmacology research.
High reported purity suitable for preclinical assays.
Supplied as a stable hydrochloride salt in solid form.
Available in small milligram pack sizes for early-stage studies.
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E/Envelope Protein Dengue virus 2 (429a a sf9 His) is the recombinant Virus-derived E/Envelope protein expressed by Sf9 insect cells with C-His labeled tag
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