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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
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m-Anisaldehyde, also known as 3-Methoxybenzaldehyde, is an endogenous metabolite found as a colorless to light yellow liquid with a density of 1.117 g/cm³. It has a chemical formula of C8H8O2 and is associated with thyroid autoimmunity during early pregnancy.
Appears as a colorless to light yellow liquid
Density of 1.117 g/cm³
Chemical formula is C8H8O2
Associated with thyroid autoimmunity during early pregnancy
Derived from plants
Soluble in various solvents including DMSO, PEG300, Tween-80, and Corn Oil
Classified as a ketone, aldehyde, and acid
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PIK-108 is a non-ATP competitive, allosteric p110β/p110δ selective inhibitor. It is suitable for research applications, particularly in studies involving PI3Kbeta-mediated Akt phosphorylation and mTORC2-mediated Akt phosphorylation.
Inhibits human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue with an IC50 of 3 nM.
Inhibits human PI3Kbeta-mediated Akt phosphorylation at T308 residue with an IC50 of 3 nM.
Inhibits mTORC2-mediated Akt phosphorylation at Ser473 residue with an IC50 of 3 nM.
Blocks phosphorylation of PKB/Akt at concentrations of 0.1-10 μM.
Soluble in DMSO at 50 mg/mL.
Clear solution with 10% DMSO, 40% PEG300, 5% Tween-80, 45% Saline at ≥ 2.08 mg/mL.
Clear solution with 10% DMSO, 90% (20% SBE-β-CD in Saline) at ≥ 2.08 mg/mL.
Clear solution with 10% DMSO, 90% Corn Oil at ≥ 2.08 mg/mL.
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