Chloroxylenol is a broad-spectrum antibacterial agent that can be used to control bacteria, algae, fungi, and viruses. It inhibits the viability, proliferation, migration, invasion, and sphere formation, and induces apoptosis in HCT116 and SW480 cells by inhibiting the Wnt/β-catenin signaling pathway. It also inhibits nuclear translocation of β-catenin in HCT116 and SW480 cells and inhibits the growth of CRC organoids. In vivo, Chloroxylenol inhibits tumor growth in a MC38 cell xenograft model.
- Broad-spectrum antibacterial agent
- Effective against bacteria, algae, fungi, and viruses
- Inhibits Wnt/β-catenin signaling pathway
- Induces apoptosis in certain cancer cells
- Inhibits tumor growth in xenograft models
- Potential for anti-cancer activity in colorectal cancer