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Amfenac Sodium Monohydrate (CAS 61618-27-7) is a synthetic non-steroidal anti-inflammatory compound structurally characterized by an acetic acid moiety It functions by inhibiting cyclooxygenase (COX) enzymes consequently suppressing prostaglandin synthesis and mitigating inflammatory processes and pain signaling Amfenac Sodium Monohydrate is utilized in biomedical research to investigate inflammatory pathways and to evaluate non-steroidal analgesic drug effects in cellular and animal models of inflammation Its well-defined inhibitory mechanism makes it a valuable tool for elucidating COX-mediated physiological and pathological responses
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Tamoxifen Citrate is a selective estrogen receptor modulator (SERM) Tamoxifen Citrate is also a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity Tamoxifen induces apoptosis and autophagy
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Cefonicid sodium salt (CAS 61270-78-8) is a second-generation cephalosporin antibiotic targeting penicillin-binding proteins (PBPs) It is designed to inhibit bacterial cell wall synthesis thereby exerting bactericidal effects against susceptible bacteria Cefonicid sodium salt acts through inhibition of bacterial cell wall synthesis by binding to PBPs In vitro studies indicate potent inhibition of pathogens such as Neisseria gonorrhoeae with minimal inhibitory concentration (MIC) values typically 2 g/mL Based on these pharmacological properties cefonicid sodium salt holds research potential for studying and treating urinary tract infections lower respiratory tract infections soft tissue infections osteomyelitis and uncomplicated gonorrhea
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Cefonicid sodium salt (CAS 61270-78-8) is a second-generation cephalosporin antibiotic targeting penicillin-binding proteins (PBPs) It is designed to inhibit bacterial cell wall synthesis thereby exerting bactericidal effects against susceptible bacteria Cefonicid sodium salt acts through inhibition of bacterial cell wall synthesis by binding to PBPs In vitro studies indicate potent inhibition of pathogens such as Neisseria gonorrhoeae with minimal inhibitory concentration (MIC) values typically 2 g/mL Based on these pharmacological properties cefonicid sodium salt holds research potential for studying and treating urinary tract infections lower respiratory tract infections soft tissue infections osteomyelitis and uncomplicated gonorrhea
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VTP50469 fumarate is a potent, highly selective, and orally active Menin-MLL interaction inhibitor. It demonstrates potent anti-leukemia activity with a Ki of 104 pM.
Inhibits cell proliferation in MLL-r and ALL cell lines
Induces apoptosis in MLL-r B cell ALL cell lines
Causes dose-dependent differentiation in MLL-r AML cell lines
Displaces Menin from protein complexes and inhibits chromatin occupancy of MLL
Leads to changes in gene expression, differentiation, and apoptosis
Shows significant survival advantage in in vivo studies in NSG mice
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Perhexiline maleate is a potent inhibitor of carnitine palmitoyltransferase 1 (CPT1) with IC50s of 77 M and 148 M for rat heart CPT1 and liver CPT1 respectively and also inhibits carnitine palmitoyltransferase 2 (CPT2)
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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