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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
Suramin is an antiparasitic drug which blocks endothelial cell proliferation and increases tyrosine phosphorylation of many signalling proteins. It is associated with urticaria paresthesias vomitingnbspand neurologic toxicity. Suramin is used to treat trypanosomiasis and onchocerciasis. It functions as an inhibitor of heparanasenbspand also exhibits anti-AIDS (acquired immunodeficiency syndrome) property.
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WAY-100635 maleate is a potent and selective 5-HT1A receptor antagonist used in pharmacological research. It is supplied as a high-purity solid or as a 10 mM solution in DMSO and is intended for in vitro and in vivo studies requiring serotonin 5-HT1A receptor blockade.
Potent, selective 5-HT1A receptor antagonist.
Available as 10 mM solution in DMSO or as solid powder.
High purity (≈99.6%) suitable for research use.
Recommended storage: solid at 4°C; solution at -20°C (short term) or -80°C (long term).
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Methiothepin maleate (CAS 19728-88-2) is a small molecule antagonist targeting serotonin receptors including 5-HT1 5-HT6 and 5-HT7 subtypes By inhibiting serotonin autoreceptors it modulates downstream signaling pathways associated with neurotransmission This compound has been widely utilized in neuroscience research to investigate the regulatory mechanisms of serotonergic signaling and to explore the pathophysiology of related neurological disorders Its ability to selectively block multiple serotonin receptor subtypes makes it a valuable tool for delineating complex neural pathways and receptor functions in experimental models
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CL 316243 disodium salt is a small-molecule agonist targeting the 3-adrenergic receptor It is designed to activate 3 receptors thereby modulating lipolytic and thermogenic pathways predominantly in adipose tissues CL 316243 disodium salt exerts its biological activity by selectively binding to 3-adrenergic receptors leading to enhanced adipocyte-mediated lipid metabolism In experimental rodent models administration of CL 316243 increases insulin sensitivity and reduces obesity-related hyperglycemia by promoting glucose uptake primarily in adipose tissue Based on these pharmacological properties CL 316243 disodium salt holds research potential in the study of 3 receptor-mediated metabolic mechanisms and the exploration of therapeutic strategies for metabolic disorders such as obesity and type 2 diabetes
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Moxalactam sodium salt (CAS 64953-12-4) is a small-molecule -lactam antibiotic belonging to the oxacephem subclass It is designed to inhibit bacterial cell wall biosynthesis by targeting penicillin-binding proteins (PBPs) Moxalactam sodium salt exerts its biological activity by interfering with PBPs thereby preventing cell wall synthesis In in vitro studies Moxalactam sodium salt demonstrates broad-spectrum inhibition of various Gram-positive Gram-negative and anaerobic bacteria including Klebsiella pneumoniae Escherichia coli Haemophilus influenzae and Neisseria gonorrhoeae Typical MIC values for susceptible organisms are generally in the low microgram-per-milliliter range Based on these pharmacological properties Moxalactam sodium salt holds research potential in antibacterial susceptibility assays studies on antibiotic resistance mechanisms and investigations of bacterial cell-wall synthesis pathways
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