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NH125 is a small-molecule inhibitor of eukaryotic elongation factor 2 kinase (eEF-2K/CaMKIII) for laboratory research. It inhibits eEF-2K with an IC50 of 60 nM and blocks eEF2 phosphorylation in intact cells, enabling studies of protein synthesis regulation, autophagy, and kinase signaling.
Potent inhibition of eEF-2K (IC50 ≈ 60 nM) for biochemical assays.
Cell-active: blocks eEF2 phosphorylation in intact cells.
Suitable for studies of translation regulation, autophagy, and kinase signaling.
Available in solid and DMSO solution formats for assay flexibility.
Storage recommendations support short-term and long-term stability when handled correctly.
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