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Organic compounds that consist of five-membered heterocyclic molecules containing a nitrogen atom and at least one other non-carbon atom as part of the ring.
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A small-molecule inhibitor of DNA polymerase eta (Pol η) supplied for research use. Provided as a solid in milligram quantities for in vitro and preclinical studies, it is suitable for mechanism-of-action experiments and combination cytotoxicity assays.
High purity: 98.0%.
Molecular weight 445.92.
Chemical formula C24H16ClN3O2S.
Provided in a 5 MG vial suitable for laboratory assays.
Intended for in vitro pharmacology and mechanism-of-action studies.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
SGC-CK2-1 is a selective, ATP-competitive chemical probe for casein kinase 2 (CK2) with low-nanomolar enzymatic potency and demonstrated cellular activity, used for target validation and mechanistic studies in kinase research.
Potent enzymatic inhibition with CK2α IC50 ≈ 4.2 nM and CK2α' IC50 ≈ 2.3 nM.
Cell-active with nanoBRET cellular IC50s in the tens of nanomolar range.
High selectivity across kinases as shown by comprehensive kinome profiling.
Molecular weight 375.44 g·mol⁻¹ and formula C20H21N7O.
Soluble up to 10 mM in DMSO; DMSO stock solutions are stable at -20 °C.
Suitable for biochemical assays and cellular target-validation studies.
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Azathioprine(BW 57-322) is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases.
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Background: A thiazole carboxylic acid used as a building block in pharmaceutical research. The carboxylic acid group allows for amide coupling and further derivatization of the thiazole heterocyclic scaffold.
Storage: Store at room temperature, under dry conditions.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More