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Organic compounds that consist of five-membered heterocyclic molecules containing a nitrogen atom and at least one other non-carbon atom as part of the ring.
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trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of *Clematis florida* var. *plena*. It exhibits anti-inflammatory activity and suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1).
Purity: 99.93%
Appearance: Solid
Color: White to light brown
Initial source: Plants Ranunculaceae
Biological activity: Suppresses NO and PGE2 production by inducing Nrf2-dependent HO-1.
Target: EP, Human endogenous metabolite
In vitro solubility: DMSO: 100 mg/mL (514.96 mM)
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cis-Urocanic acid is a 5-HT2A receptor agonist that binds to the 5-HT receptor with relatively high affinity (Kd=4.6 nM). This compound acts as an immune modulator, inducing immunosuppression through its binding to the 5-HT2A receptor.
5-HT2A receptor agonist.
Immune modulator that induces immunosuppression by binding to the 5-HT2A receptor.
Treatment with 100 μg/mL completely suppresses IL-6 and IL-8 secretion.
Decreases caspase-3 activity.
Improves cell viability against UV-B irradiation in human corneal epithelial cells (HCE-2) and human conjunctival epithelial cells (HCECs).
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RAD16-I hydrochloride is a soft nanofibrous self-assembling peptide. It provides a suitable microenvironment for human mesenchymal stem cells' (hMSC) proliferation and differentiation into chondrocytes. This ionic complementary peptide is also used as a model to check potential amyloid-like staining properties of self-assembling peptide nanofibers (SAPNFs).
Provides a suitable microenvironment for human mesenchymal stem cells' (hMSC) proliferation and differentiation into chondrocytes.
Used as a model to check potential amyloid-like staining properties of self-assembling peptide nanofibers (SAPNFs).
Intended for research use only.
Suitable for laboratory use.
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1-Trityl-1H-imidazole-4-carbaldehyde is a biochemical reagent used as a biological material or organic compound for life science-related research. It is for research use only and not intended for medical applications.
Used as a biochemical reagent
Applicable in life science-related research
Used in the synthesis of histamine and girolline (in vitro)
Appears as a white to off-white solid
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Medchemexpress, HY-A0006 10mg Pentostatin CAS:53910-25-1 Pentostatin (CI-825; Deoxycoformycin) is an irreversible inhibitor of adenosine deaminase with Ki of 2.5 pM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress, HY-19708 10mg KIRA6 CAS:1589527-65-0 KIRA6 is an advanced small-molecule IRE1α RNase kinase inhibitor with an IC50 of 0.6 µM[2]. KIRA6 can trigger an apoptotic response. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Aminothiazole (96-50-4) is a small-molecule inhibitor targeting thyroid peroxidase It is designed to interfere with thyroid hormone biosynthesis thereby regulating thyroid hormone levels Aminothiazole exerts its biological activity primarily through inhibition of the thyroid peroxidase enzyme In in vitro studies aminothiazole demonstrates inhibitory activity with an IC50 value typically ranging from 1 to 10 M Based on these pharmacological properties aminothiazole holds research potential in the investigation of thyroid hormone regulatory mechanisms and pathologies such as hyperthyroidism as well as in antimicrobial screening assays
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Medchemexpress, HY-100020 50mg BAY-1436032 CAS:1803274-65-8 BAY-1436032 is a novel pan-mutant isocitrate dehydrogenase 1 ( IDH1 ) inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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