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Organic compounds that consist of five-membered heterocyclic molecules containing a nitrogen atom and at least one other non-carbon atom as part of the ring.
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Methyl methanesulfonate is an alkylating agent that transfers methyl groups and induces DNA damage. It is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Induces DNA damage
Biochemical reagent for life science research
Acts as a DNA alkylator/crosslinker
Involved in necroptosis pathways
Targets MDM-2/p53 and reactive oxygen species (ROS)
Upregulates generation of phosphorylated p53, RIPK, and ROS in A549 cells
Induces necroptosis in cell A549
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MTT (CAS 298-93-1) chemically known as 3-(4 5-Dimethylthiazol-2-yl)-2 5-diphenyl-2H-tetrazolium bromide is a tetrazolium salt commonly employed in biomedical research to assess cellular proliferation and metabolic activity in vitro Upon uptake by viable cells MTT undergoes reduction primarily mediated by NADH-dependent oxidoreductases in mitochondria and partly by extra-mitochondrial enzymes forming insoluble formazan precipitates The resulting formazan accumulation correlates with metabolic activity and cell viability Due to its membrane-permeable cationic nature MTT efficiently penetrates intact cell membranes without requiring intermediates distinguishing it from second-generation negatively charged tetrazolium derivatives
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m-Isobutyl ibuprofen is a synthetic impurity (Ibuprofen impurity A) encountered during the manufacture of ibuprofen. It is supplied for research and analytical purposes as a small-mass reference standard used in impurity profiling, method development, and quality control. CAS 66622-47-7; molecular formula C13H18O2.
Intended for research use and analytical reference.
Suitable as an impurity reference for HPLC and GC method development.
Available in small pack sizes for laboratory workflows.
Provided with data sheet and certificate of analysis for lot-specific details.
Store under recommended conditions; consult certificate of analysis for stability information.
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Atopaxar is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist. As an antiplatelet agent, it interferes with platelet signaling and can be used for the research of atherothrombotic disease.
Potent, orally active, selective and reversible PAR-1 antagonist
Interferes with platelet signaling
Used for research of atherothrombotic disease
Inhibits human platelet aggregation induced by thrombin or TRAP
Does not inhibit PRP aggregation induced by ADP, U46619, collagen, and PAR-4ap, up to 20 μM
Causes dose-dependent prolongation of time to occlusion of the femoral artery in photochemically-induced thrombosis (PIT) guinea pigs model
Does not prolong bleeding time in guinea pigs at high dosages
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Coblopasvir dihydrochloride is a pangenotypic non-structural protein 5A (NS5A) inhibitor supplied as a solid research compound for preclinical studies of hepatitis C virus (HCV) replication and NS5A function. It is provided in a small research quantity with high reported purity and recommended storage conditions to maintain stability.
Pangenotypic NS5A inhibitor for HCV research.
Supplied as a solid research reagent for biochemical and virology studies.
High reported purity (99.19%) to support experimental consistency.
Chemical formula C41H52Cl2N8O8; molecular weight 855.81 g·mol⁻¹.
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Coblopasvir dihydrochloride is a pangenotypic non-structural protein 5A (NS5A) inhibitor supplied for research use in studies of chronic hepatitis C virus infection. The compound is provided as the dihydrochloride salt and is intended for in vitro and preclinical research applications.
Pangenotypic NS5A inhibitor for HCV research.
Supplied as the dihydrochloride salt for improved stability and handling.
High purity (≈98.5%) suitable for analytical and biological studies.
Available in multiple pack sizes, including 25 mg and solution formats.
Delivered with batch-specific certificate of analysis.
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