Azoles
Medchemexpress LLC Methyl methanesulfonate | 66-27-3 | 110.13 | 1 ML
Methyl methanesulfonate is an alkylating agent that transfers methyl groups and induces DNA damage. It is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- Induces DNA damage
- Biochemical reagent for life science research
- Acts as a DNA alkylator/crosslinker
- Involved in necroptosis pathways
- Targets MDM-2/p53 and reactive oxygen species (ROS)
- Upregulates generation of phosphorylated p53, RIPK, and ROS in A549 cells
- Induces necroptosis in cell A549
Medchemexpress LLC DIM-C-pPhOH | 151358-47-3 | 99.0% | 338.40 | 1 MG
DIM-C-pPhOH | 151358-47-3 | 99.0% | 338.40 | 1 MG
Medchemexpress LLC M-isobutyl ibuprofen | 66622-47-7 | MFCD08275582 | ≥98.0% | C13H18O2 | 10MG
m-Isobutyl ibuprofen is a synthetic impurity (Ibuprofen impurity A) encountered during the manufacture of ibuprofen. It is supplied for research and analytical purposes as a small-mass reference standard used in impurity profiling, method development, and quality control. CAS 66622-47-7; molecular formula C13H18O2.
- Intended for research use and analytical reference.
- Suitable as an impurity reference for HPLC and GC method development.
- Available in small pack sizes for laboratory workflows.
- Provided with data sheet and certificate of analysis for lot-specific details.
- Store under recommended conditions; consult certificate of analysis for stability information.
Medchemexpress LLC N7-methyl-guanosine-5'-triphosphate-5'-adenosine diammonium | 75252-10-7 | C21H35N12O17P3 | 10MG
m7G(5')ppp(5')A diammonium is a dinucleotide 5' cap analog that mimics the natural eukaryotic mRNA cap structure. It is used to produce capped RNA in vitro for studies of translation initiation, mRNA stability, and cap-binding protein interactions.
- Mimics natural 5' mRNA cap for biologically relevant capping.
- Suitable for in vitro transcription and translation assays.
- High purity (>99%) supports reproducible experimental results.
- Solid, white to off-white material simplifies handling and storage.
- Stable under recommended storage conditions for consistent performance.
Apexbio Technology LLC DIM-C-pPhOH 151358-47-3 25mg
DIM-C-pPhOH (CAS 151358-47-3) is a small-molecule antagonist that targets the nuclear receptor NR4A1 (nuclear receptor subfamily 4 group A member 1) It has been shown to inhibit tumor cell proliferation by modulating the mTOR signaling pathway induce apoptosis and activate cellular stress responses In in vitro studies using human renal carcinoma cell lines ACHN and 786-O DIM-C-pPhOH demonstrated inhibitory effects on cell proliferation with IC50 values of 13 6 M and 13 0 M respectively This compound serves as a valuable tool for investigating tumor-associated signaling pathways and the mechanisms underlying anticancer therapeutics
Apexbio Technology LLC ET SSB Protein 100ug
ET SSB Protein is a recombinant protein that selectively binds to single-stranded DNA (ssDNA) It is designed to stabilize unfolded DNA regions and prevent strand reassociation or nuclease degradation ET SSB Protein exerts its biological activity primarily by binding ssDNA maintaining DNA in a single-stranded state and withstanding incubation at temperatures up to 95 C Based on these properties ET SSB Protein holds research potential in PCR and q-PCR assay optimization enhancement of DNA polymerase performance stabilization and labeling of ssDNA facilitation of reverse transcriptase efficiency in RT-PCR and sequencing protocols involving strong secondary structures
Apexbio Technology LLC DIM-C-pPhOH 151358-47-3 10mg
DIM-C-pPhOH (CAS 151358-47-3) is a small-molecule antagonist that targets the nuclear receptor NR4A1 (nuclear receptor subfamily 4 group A member 1) It has been shown to inhibit tumor cell proliferation by modulating the mTOR signaling pathway induce apoptosis and activate cellular stress responses In in vitro studies using human renal carcinoma cell lines ACHN and 786-O DIM-C-pPhOH demonstrated inhibitory effects on cell proliferation with IC50 values of 13 6 M and 13 0 M respectively This compound serves as a valuable tool for investigating tumor-associated signaling pathways and the mechanisms underlying anticancer therapeutics
Apexbio Technology LLC ET SSB Protein 500ug
ET SSB Protein is a recombinant protein that selectively binds to single-stranded DNA (ssDNA) It is designed to stabilize unfolded DNA regions and prevent strand reassociation or nuclease degradation ET SSB Protein exerts its biological activity primarily by binding ssDNA maintaining DNA in a single-stranded state and withstanding incubation at temperatures up to 95 C Based on these properties ET SSB Protein holds research potential in PCR and q-PCR assay optimization enhancement of DNA polymerase performance stabilization and labeling of ssDNA facilitation of reverse transcriptase efficiency in RT-PCR and sequencing protocols involving strong secondary structures
Medchemexpress LLC (E)-3-((1H-indol-3-yl)methylene)-5-((E)-3,4-dimethoxybenzylidene)-1-methylpiperidin-4-one | 1370032-19-1 | 99.1% | 388.46 g/mol | C24H24N2O3 | 5 MG
CA-5f is a small-molecule late-stage macroautophagy inhibitor that blocks autophagosome-lysosome fusion, elevates LC3B-II and SQSTM1/p62, increases reactive oxygen species, and has reported antitumor activity in cellular studies. Supplied for research use in solid form and as ready-to-use DMSO solutions; documentation is available for quality control.
- Blocks autophagosome-lysosome fusion in autophagy assays.
- Modulates LC3B-II and SQSTM1/p62 levels for pathway studies.
- Induces reactive oxygen species in cell-based assays.
- Available as solid and DMSO solution formats for flexibility.
- High reported purity suitable for biochemical and cellular experiments.
- Documentation includes datasheet, COA, and SDS for quality control.
Medchemexpress LLC Endo S2 S. pyogenes 5ug | 5ug
Endo S2 secreted by Streptococcus pyogenes deglycosylates the conserved N-linked glycan at Asn297 on IgG Fc to eliminate its effector functions and evade the immune system EndoS2 specifically hydrolyzes diverse glycans on the Fc region of IgG antibodies using a mechanism that relies on its glycoside hydrolase domain and a coevolved carbohydrate-binding module[1][2] Endo S2 Protein S pyogenes (His) is the recombinant Endo S2 protein expressed by E coli with N-6 His labeled tag
AdipoGen Hoechst 33342, 23491-52-3, MFCD00166996, 25 mg
MF: C27H28N6O . 3HCl . xH2O, MW: 561.93, ≥98%, Appearance: Yellow to yellow-green crystalline solid. Useful for staining DNA, chromosomes and nuclei. May be used for fluorescence microscopy or flow cytometry. Suitable for vital DNA staining of a variety of cell types and as a probe of membrane permeability in mammalian cells.