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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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3'-Deoxy-3'-fluorouridine is a fluorinated uridine analogue used in biochemical and oncology research as a probe of nucleoside metabolism and as a research compound in antitumor studies. It is supplied as an off-white powder for laboratory use; consult the product SDS for handling and storage requirements.
Chemical name: 3'-deoxy-3'-fluorouridine.
CAS number 57944-13-5.
Molecular formula C9H11FN2O5.
Molecular weight 246.19 g/mol.
Purity >95.0%.
Appearance off-white to white powder.
Storage recommended -20 °C, dry and protected from moisture.
Typical packaging 10 mg vial.
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LUF6096 is a potent allosteric enhancer of the adenosine A3 receptor, which is able to allosterically enhance agonist binding. It shows low orthosteric affinity for any of the adenosine receptors. LUF6096 also demonstrates protective effects in myocardial ischemia/reperfusion injury.
Enhances agonist binding to adenosine A3 receptor
Exhibits low orthosteric affinity for adenosine receptors
Provides protective effects in myocardial ischemia/reperfusion injury
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3-Bromopyruvic acid (CAS 1113-59-3) abbreviated as 3-BP is a small molecule inhibitor that targets hexokinase II (HK2) an enzyme notably upregulated in cancerous cells By inhibiting HK2 activity (Ki 2 4 mM) 3-BP interferes with glycolytic energy metabolism leading to reduced tumor cell proliferation in hepatocellular carcinoma BEL-7402 cells In mouse xenograft models of hepatocellular carcinoma administration of 3-BP (50 mg/kg/day six days weekly for three weeks) results in decreased tumor growth and increased tumor necrosis This compound serves as a tool in oncology research particularly for studying glycolysis-dependent tumor metabolism
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