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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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2'-Fluoro-2'-deoxy-ara-C(Bz)-3'-phosphoramidite is a cytidine analog that works by inhibiting DNA methyltransferases. This compound shows potential anti-metabolic and anti-tumor activities.
Cytidine analog
Inhibits DNA methyltransferases
Possesses potential anti-metabolic activities
Possesses potential anti-tumor activities
High purity (99.84%)
Appears as a white to off-white solid
Stable under recommended storage conditions
For research use only
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3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells. It also inhibits HIV-1 reverse transcriptase with an EC50 of 0.06 μM in peripheral blood mononuclear (PBM) cells. This compound is a click chemistry reagent, containing an Azide group, and can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Inhibits HIV-1 at an EC50 of 0.06 μM in PBM cells
Inhibits XMRV at a CC50 of 43.5 μM in MCF-7 cells
Functions as a click chemistry reagent
Contains an Azide group for CuAAc reactions with Alkyne groups
Participates in SPAAC reactions with DBCO or BCN groups
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11-Deoxy Prostaglandin E2 is a selective agonist of EP4 with an EC50 of 0 66 nM 11-Deoxy Prostaglandin E2 is an analog of prostaglandin E2 11-Deoxy Prostaglandin E2 can be used in study bone healing heart failure and other receptor associated conditions[1][2]
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6A-Azido-6A-deoxy-β-cyclodextrin is a mono-azido functionalized β-cyclodextrin supplied as a solid. It provides an azide handle for copper-catalyzed azide-alkyne cycloaddition (click chemistry) and is used for bioconjugation, drug-delivery research, and surface modification. High purity and defined molecular weight support analytical and synthetic workflows.
Mono-azido functionality for efficient click chemistry reactions.
High purity (98.0%) suitable for research applications.
Water-soluble cyclodextrin derivative for host-guest studies.
Good solubility in DMSO; ultrasonic assistance recommended.
Supplied as a solid for convenient handling and storage.
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5'-Deoxy-5'-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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5'-Deoxy-5'-iodouridine is a purine nucleoside analog. Purine nucleoside analogs exhibit broad antitumor activity, specifically targeting indolent lymphoid malignancies. The anticancer mechanisms involved include the inhibition of DNA synthesis and the induction of apoptosis.
It is a purine nucleoside analog.
Demonstrates broad antitumor activity.
Targets indolent lymphoid malignancies.
Functions by inhibiting DNA synthesis.
Induces apoptosis.
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3'-Deoxy-3'-fluorouridine is a purine nucleoside analog with a molecular formula of C9H11FN2O5. It appears as a white to off-white solid and has a high purity of 99.66% as determined by LCMS. This product is intended for research use only and has not been fully validated for medical applications.
White to off-white solid appearance
Purity of 99.66% (LCMS)
Consistent with structure based on 1H NMR spectrum and LCMS
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2'-Fluoro-2'-deoxy-ara-A(Bz)-3'-phosphoramidite is an adenosine analog. Adenosine analogs primarily act as smooth muscle vasodilators and have also been shown to inhibit cancer progression.
Adenosine analog
Acts as a smooth muscle vasodilator
Inhibits cancer progression
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2'-Deoxy-N2-methylguanosine, a DNA adduct, is classified as a purine nucleoside analog. These analogs demonstrate broad antitumor activity, specifically targeting indolent lymphoid malignancies. The anticancer mechanisms involved include the inhibition of DNA synthesis and the induction of apoptosis.
Molecular weight: 281.27
Appearance: Solid
Color: Off-white to light yellow
Purity: 99.82%
Solubility (in vitro): DMSO : 12.5 mg/mL (44.44 mM)
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2'-Deoxy-N2-methylguanosine, a DNA adduct, is a purine nucleoside analog. These analogs are known to have broad antitumor activity, particularly against indolent lymphoid malignancies.
DNA adduct
Purine nucleoside analog
Exhibits broad antitumor activity against indolent lymphoid malignancies
Anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis
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2'-Deoxy-N1-methylguanosine is a purine nucleoside analog that exhibits broad antitumor activity, specifically targeting indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis.
Purine nucleoside analog
Exhibits broad antitumor activity
Targets indolent lymphoid malignancies
Inhibits DNA synthesis
Induces apoptosis
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