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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
An alkylating agent and antimetabolite of pyruvate; decreases proliferation of BEL-7402 cells expressing hexokinase II; reduces tumor growth and induces tumor necrosis in a hepatocellular carcinoma mouse xenograft model at 50 mg/kg per day, six days per week, for three weeks
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Pyruvic acid (Standard) is the analytical standard of Pyruvic acid This product is intended for research and analytical applications Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates proteins and fats
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Pyruvic acid-13C-2 (sodium) is the 13C labeled Pyruvic acid[1] Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates proteins and fats[2]
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3-Bromopyruvic acid is an analogue of pyruvate and a potent hexokinase (HK)-II inhibitor with high tumor selectivity. It inhibits cell growth and induces apoptosis through interfering with glycolysis. This compound also induces autophagy by stimulating ROS formation in breast cancer cells, and exhibits antimicrobial activities.
Potent hexokinase (HK)-II inhibitor with high tumor selectivity.
Inhibits cell growth and induces apoptosis through interfering with glycolysis.
Induces autophagy by stimulating ROS formation in breast cancer cells.
Exhibits antimicrobial activities.
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3-Bromopyruvic acid (CAS 1113-59-3) abbreviated as 3-BP is a small molecule inhibitor that targets hexokinase II (HK2) an enzyme notably upregulated in cancerous cells By inhibiting HK2 activity (Ki 2 4 mM) 3-BP interferes with glycolytic energy metabolism leading to reduced tumor cell proliferation in hepatocellular carcinoma BEL-7402 cells In mouse xenograft models of hepatocellular carcinoma administration of 3-BP (50 mg/kg/day six days weekly for three weeks) results in decreased tumor growth and increased tumor necrosis This compound serves as a tool in oncology research particularly for studying glycolysis-dependent tumor metabolism
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Indole-3-pyruvic acid-d5 is deuterated labeled Indole-3-pyruvic acid Indole-3-pyruvic acid a keto analogue of tryptophan is an orally active AHR agonist Indole-3-pyruvic acid has antioxidant properties and can be used in the research of inflammation anxiety[1][2][3]
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3-Bromopyruvic acid (CAS 1113-59-3) abbreviated as 3-BP is a small molecule inhibitor that targets hexokinase II (HK2) an enzyme notably upregulated in cancerous cells By inhibiting HK2 activity (Ki 2 4 mM) 3-BP interferes with glycolytic energy metabolism leading to reduced tumor cell proliferation in hepatocellular carcinoma BEL-7402 cells In mouse xenograft models of hepatocellular carcinoma administration of 3-BP (50 mg/kg/day six days weekly for three weeks) results in decreased tumor growth and increased tumor necrosis This compound serves as a tool in oncology research particularly for studying glycolysis-dependent tumor metabolism
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More