Aminobenzoic acids and derivatives
Medchemexpress LLC Reboxetine mesylate | 98769-84-7 | MFCD02184016 | 99.7% | 409.50 g·mol⁻1 | C20H27NO6S | 5 MG
Reboxetine mesylate is the methanesulfonate salt of reboxetine, a selective noradrenaline reuptake inhibitor used as a research compound to study norepinephrine transporter function and neuropharmacology. It is supplied as a high-purity research chemical for in vitro and in vivo experimental applications; CAS 98769-84-7, molecular weight 409.50 g·mol⁻1.
- Selective noradrenaline reuptake inhibitor activity for transporter studies.
- Suitable for in vitro and in vivo research applications.
- High purity suitable for analytical and pharmacological assays.
- Available in small milligram quantities for laboratory use.
- Provided with referenced product documentation and datasheet.
Medchemexpress LLC Pritelivir (mesylate hydrate) | 1428321-10-1 | C19H24N4O7S3 | 25 MG
Pritelivir (mesylate hydrate) | 1428321-10-1 | C19H24N4O7S3 | 25 MG
Medchemexpress LLC Obatoclax mesylate | 803712-79-0 | 99.9% | 413.49 | 1 ML
Obatoclax Mesylate is a BH3 mimetic and a pan-BCL-2 family proteins inhibitor that induces autophagy-dependent cell death and targets cyclin D1 for proteasomal degradation. It exhibits anti-cancer and broad-spectrum antiparasitic activity.
- Inhibits BCL-2 family proteins including BCL-2, BCL-XL, MCL-1, BCL-w, A1, and BCL-b
- Induces autophagy-dependent cell death
- Targets cyclin D1 for proteasomal degradation
- Demonstrates anti-cancer and broad-spectrum antiparasitic activity
- Reduces cell numbers in human colorectal cancer cell lines (HCT116, HT-29, LoVo)
- Increases G1-phase cell populations
- Causes a marked drop in cyclin D1 levels, inhibits GSK3β, and activates p38MAPK
- Shows potent antitumor activity in xenograft mouse models
Apexbio Technology LLC KB-R7943 mesylate 182004-65-5 50mg
KB-R7943 mesylate (CAS 182004-65-5) is a selective inhibitor of the Na /Ca2 exchanger (NCX) particularly effective against its reverse mode It inhibits NCX-mediated Ca2 influx with an IC50 of 0 7 M In transfected Chinese hamster ovary (CHO) cells expressing NCX KB-R7943 suppresses exchanger activity at high intracellular Na concentrations In cultured rat forebrain neurons it attenuates Ca2 transients induced by glutamate NMDA kainate or KCl with IC50 values ranging from 2 9 to 8 2 M In in vivo studies KB-R7943 reduces endothelin-1 levels and mitigates acute renal dysfunction following ischemic injury This compound is widely utilized in studies investigating Na /Ca2 exchange and related calcium signaling pathways
Apexbio Technology LLC Nafamostat 81525-10-2 10mg
Nafamostat (CAS 81525-10-2) is a small-molecule inhibitor targeting a broad spectrum of serine proteases including thrombin plasmin kallikrein and human trypsin It is designed to block protease-mediated hydrolysis reactions thereby regulating coagulation pathways and inflammation-related protease activity Nafamostat exerts its biological activity primarily through reversible binding to protease active sites inhibiting their enzymatic functions In biochemical assays Nafamostat demonstrates potent inhibitory activity with an IC50 value of approximately 1 10 nM against human trypsin Based on these pharmacological properties Nafamostat holds research potential in coagulation pathway studies inflammation-related protease research pancreatitis modeling and mechanistic investigations of blood coagulation disorders and inflammatory responses
Aobchem 4-(4-Methylbenzyl)benzoic acid | 97% | CAS 70121-78-7 | C15H14O2 | 1g
4-(4-Methylbenzyl)benzoic acid | 97% | CAS 70121-78-7 | C15H14O2 | 1g
Aobchem 4-(4-Formylphenoxy)benzoic acid | 97% | CAS 2509-18-4 | C14H10O4 | 250mg
4-(4-Formylphenoxy)benzoic acid | 97% | CAS 2509-18-4 | C14H10O4 | 250mg
Aobchem 5-Ethoxy-2 4-dimethylbenzoic acid | 97% | CAS 2091216-89-4 | C11H14O3 | 250mg
5-Ethoxy-2 4-dimethylbenzoic acid | 97% | CAS 2091216-89-4 | C11H14O3 | 250mg
Aobchem Methyl 7-methylbenzo[b]thiophene-2-carboxylate | 97% | CAS 3751-50-6 | C11H10O2S | 1g
Methyl 7-methylbenzo[b]thiophene-2-carboxylate | 97% | CAS 3751-50-6 | C11H10O2S | 1g