Aminobenzoic acids and derivatives
Medchemexpress LLC Pamufetinib mesylate | 1688673-09-7 | 99.2% | 614.66 | C28H27FN4O7S2 | 25MG
Pamufetinib mesylate is a research-stage small-molecule kinase inhibitor that targets vascular endothelial growth factor receptors (VEGFR) and hepatocyte growth factor receptor (c-Met/HGFR). It exhibits low-nanomolar inhibition of recombinant VEGFR2 and MET and is used in preclinical studies of angiogenesis and MET-driven signaling in oncology research. The compound is provided as the mesylate salt for laboratory use and should be stored under controlled conditions to maintain stability.
- Provides low-nanomolar inhibition of VEGFR2 and MET (IC50 ≈ 30-32 nM).
- Suitable for preclinical studies of angiogenesis and MET-dependent signaling.
- High chemical purity as confirmed by batch analysis (~99.2%).
- Mesylate salt form for convenient laboratory handling.
- Stable when stored under recommended conditions to preserve activity.
Medchemexpress LLC Pamufetinib mesylate | 1688673-09-7 | 99.2% | 614.66 | C28H27FN4O7S2 | 10MG
Pamufetinib mesylate is the methanesulfonate (mesylate) salt of pamufetinib (TAS-115), a small-molecule tyrosine kinase inhibitor that targets vascular endothelial growth factor receptors (VEGFR) and hepatocyte growth factor receptor (c-Met/HGFR). It exhibits low-nanomolar biochemical potency (IC50 = 30 nM for rVEGFR2; 32 nM for rMET) and is supplied as a high-purity solid for research use.
- Dual inhibition of VEGFR and c-Met with low-nanomolar potency.
- Provided as the mesylate salt to enhance handling and stability.
- High purity (>99.1%) suitable for biochemical and cell assays.
- Soluble in DMSO (~75 mg/mL), enabling preparation of concentrated stocks.
- Storage recommendations include refrigerated, moisture-protected storage; in solvent long-term at -80°C.
- Available in research pack sizes appropriate for in vitro and in vivo studies.
Medchemexpress LLC Pamufetinib mesylate | 1688673-09-7 | 99.2% | 614.66 g/mol | C28H27FN4O7S2 | 100MG
Pamufetinib mesylate is an ATP-competitive, small-molecule inhibitor that targets vascular endothelial growth factor receptor (VEGFR) and hepatocyte growth factor receptor (c-Met/HGFR). Supplied as the mesylate salt for research use only, it exhibits potent in vitro kinase inhibition and is provided as a high-purity solid with recommended storage conditions to preserve stability.
- Potent dual inhibition of VEGFR2 and MET (IC50 ≈ 30-32 nM).
- High reported purity (99.2%).
- Provided as a mesylate salt to improve handling and solubility for assays.
- Available in a 100 mg pack size for research applications.
- Solid, white to off-white appearance suitable for accurate weighing.
- Storage recommendations: 4°C for powder; in solvent -80°C for long-term stability.
Medchemexpress LLC Pamufetinib mesylate | 1688673-09-7 | 99.2% | 614.66 g/mol | C28H27FN4O7S2 | 50MG
Pamufetinib mesylate is a research-grade small-molecule multi-kinase inhibitor that targets vascular endothelial growth factor receptor (VEGFR) and hepatocyte growth factor receptor (c-Met/HGFR). It exhibits potent activity in biochemical assays, with reported IC50 values near 30 nM for VEGFR2 and 32 nM for MET, and is intended for in vitro and preclinical research use only.
- High purity suitable for research (reported 99.17%).
- Potent VEGFR and c-Met inhibition (IC50 ~30-32 nM).
- Available as solid and DMSO solution formats for assay flexibility.
- Characterized molecular weight and formula for analytical work.
- Supplied in multiple pack sizes to support diverse study scales.
Medchemexpress LLC Pamufetinib mesylate | 1688673-09-7 | 99.2% | 614.66 g·mol-1 | C28H27FN4O7S2 | 10MM 1ML
Pamufetinib mesylate is the methanesulfonate salt of a small-molecule kinase inhibitor that targets VEGFR and hepatocyte growth factor receptor (c-Met/HGFR). Supplied as a 10 mM solution in DMSO (1 mL) for in vitro research use, it demonstrates potent activity with reported IC50 values of 30 nM (rVEGFR2) and 32 nM (rMET). Molecular formula: C28H27FN4O7S2; molecular weight: 614.66 g·mol-1. Purity: 99.17%.
- Supplied as a ready-to-use 10 mM solution in DMSO.
- Suitable for in vitro kinase inhibition assays.
- Potent VEGFR and c-Met inhibitor with low-nanomolar IC50 values.
- High chemical purity (99.17%).
- For research use only; not for human or veterinary use.
Chemscene 3 4 -Dihydroxyacetophenone | 25g | CS-W008953 | 98% | 1197-09-7 | MFCD00016439 | 152 15 | C8H8O3
Chemscene | 3 4 -Dihydroxyacetophenone | 25g | CS-W008953 | 98% | 1197-09-7 | MFCD00016439 | 152 15 | C8H8O3
Chemscene (E)-Crotonic acid | 100g | CS-0017976 | 98% | 107-93-7 | MFCD00002701 | 86 09 | C4H6O2
Chemscene | (E)-Crotonic acid | 100g | CS-0017976 | 98% | 107-93-7 | MFCD00002701 | 86 09 | C4H6O2
Chemscene (E)-Crotonic acid | 500g | CS-0017976 | 98% | 107-93-7 | MFCD00002701 | 86 09 | C4H6O2
Chemscene | (E)-Crotonic acid | 500g | CS-0017976 | 98% | 107-93-7 | MFCD00002701 | 86 09 | C4H6O2
Chemscene D-tert-Leucinol | 25g | CS-W008332 | 98% | 112245-09-7 | MFCD01076574 | 117 19 | C6H15NO
Chemscene | D-tert-Leucinol | 25g | CS-W008332 | 98% | 112245-09-7 | MFCD01076574 | 117 19 | C6H15NO
Chemscene 3 4 -Dihydroxyacetophenone | 5g | CS-W008953 | 98% | 1197-09-7 | MFCD00016439 | 152 15 | C8H8O3
Chemscene | 3 4 -Dihydroxyacetophenone | 5g | CS-W008953 | 98% | 1197-09-7 | MFCD00016439 | 152 15 | C8H8O3
Chemscene D-tert-Leucinol | 100g | CS-W008332 | 98% | 112245-09-7 | MFCD01076574 | 117 19 | C6H15NO
Chemscene | D-tert-Leucinol | 100g | CS-W008332 | 98% | 112245-09-7 | MFCD01076574 | 117 19 | C6H15NO
Chemscene D-tert-Leucinol | 10g | CS-W008332 | 98% | 112245-09-7 | MFCD01076574 | 117 19 | C6H15NO
Chemscene | D-tert-Leucinol | 10g | CS-W008332 | 98% | 112245-09-7 | MFCD01076574 | 117 19 | C6H15NO
Chemscene 3 4 -Dihydroxyacetophenone | 10g | CS-W008953 | 98% | 1197-09-7 | MFCD00016439 | 152 15 | C8H8O3
Chemscene | 3 4 -Dihydroxyacetophenone | 10g | CS-W008953 | 98% | 1197-09-7 | MFCD00016439 | 152 15 | C8H8O3
Chemscene D-tert-Leucinol | 250mg | CS-W008332 | 98% | 112245-09-7 | MFCD01076574 | 117 19 | C6H15NO
Chemscene | D-tert-Leucinol | 250mg | CS-W008332 | 98% | 112245-09-7 | MFCD01076574 | 117 19 | C6H15NO
Chemscene D-tert-Leucinol | 5g | CS-W008332 | 98% | 112245-09-7 | MFCD01076574 | 117 19 | C6H15NO
Chemscene | D-tert-Leucinol | 5g | CS-W008332 | 98% | 112245-09-7 | MFCD01076574 | 117 19 | C6H15NO
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