Benzenesulfonamides
![Medchemexpress LLC 7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene | 84030-20-6 | MFCD00043004 | 99.2% | C8H15N3 | 500 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC 7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene | 84030-20-6 | MFCD00043004 | 99.2% | C8H15N3 | 500 MG
7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene is a drug intermediate used for the synthesis of various active compounds. This product is intended for research use only.
- Purity: 99.2%
- Molecular weight: 153.23
- Chemical formula: C8H15N3
- CAS number: 84030-20-6
- Appearance: Liquid
- Color: Colorless to light yellow
- Storage conditions:
- Pure form: -20°C for 3 years, 4°C for 2 years
- In solvent: -80°C for 6 months, -20°C for 1 month
Chem-Impex International, Inc. 2-Nitrobenzenesulfonamide | MFCD00009807 | 100G
2-Nitrobenzenesulfonamide, MFCD00009807, 100G
Medchemexpress LLC Sulfacetamide sodium | 127-56-0 | 99.7% | 25 G
Sulfacetamide sodium is a sulfonamide antibiotic that can be used for the study of ocular infections. It exhibits antifungal and antibacterial activities.
- Used for the study of various ocular infections like trachoma, blepharitis, conjunctivitis, corneal ulcer, pityriasis versicolor, and rosacea
- Acts as an antifungal agent through a CYP51A1-independent mechanism
- Bacteriostatic agent with similar activity against both Gram-positive and Gram-negative bacteria
Medchemexpress LLC Sulfacetamide sodium monohydrate | 6209-17-2 | >99.5% | 10 G
Sulfacetamide sodium monohydrate is a sulfonamide antibiotic effective against ocular infections. It exhibits antifungal and antibacterial activities, making it suitable for studying conditions like trachoma, blepharitis, conjunctivitis, and corneal ulcers.
- Acts as an antifungal drug through a CYP51A1-independent mechanism
- Functions as a bacteriostatic agent
- Effective against both Gram-positive and Gram-negative bacteria
- Can be used for the study of various ocular infections
Sigma Aldrich Fine Chemicals Biosciences (+/-)-Sulpiride | 15676-16-1 | MFCD00055061 | 25G
(+/-)-Sulpiride | Mol Wt: 341.43 | 15676-16-1 | MFCD00055061 | 25G
Medchemexpress LLC HY-15025A 50mg Medchemexpress, Sildenafil (citrate) CAS:171599-83-0 Purity:>98%
Medchemexpress, HY-15025A 50mg Sildenafil (citrate) CAS:171599-83-0 Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with IC50 of 5.22 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![Medchemexpress LLC 5-(2-ethoxy-5-piperazin-1-ylsulfonylphenyl)-1-methyl-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-7-one | 139755-82-1 | MFCD00908398 | 99.5% | 460.55 | C21H28N6O4S | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000227669.png-250.jpg)
Medchemexpress LLC 5-(2-ethoxy-5-piperazin-1-ylsulfonylphenyl)-1-methyl-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-7-one | 139755-82-1 | MFCD00908398 | 99.5% | 460.55 | C21H28N6O4S | 5 MG
N-Desmethyl sildenafil is the primary N-desmethyl metabolite of sildenafil and is provided as a high-purity analytical standard for research, pharmacokinetic, and method development applications. It is a solid white to off-white compound with confirmed molecular formula C21H28N6O4S and a molecular weight of approximately 460.6 g/mol.
- Major metabolite of sildenafil for metabolism studies.
- High purity suitable for analytical and quantitative assays.
- Available in small solid packages and as a solution for analytical use.
- White to off-white solid with consistent lot-specific certificate of analysis.
- Recommended storage at low temperatures for long-term stability.
- Used in pharmacology and method validation workflows.
![Medchemexpress LLC 5-[6-[[(3R)-1-azabicyclo[2.2.2]octan-3-yl]oxy]pyridazin-3-yl]-1H-indole | 855291-54-2 | 99.7% | 320.39 g/mol | C19H20N4O | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000242979.png-250.jpg)
Medchemexpress LLC 5-[6-[[(3R)-1-azabicyclo[2.2.2]octan-3-yl]oxy]pyridazin-3-yl]-1H-indole | 855291-54-2 | 99.7% | 320.39 g/mol | C19H20N4O | 10 MG
ABT-107 is a selective α7 neuronal nicotinic acetylcholine receptor agonist used in preclinical research to probe α7-mediated signaling and neuroprotection. It has shown protection against nigrostriatal damage in rodent models and is supplied for both in vitro and in vivo experimental applications.
- Selective α7 neuronal nicotinic receptor agonist suitable for receptor pharmacology studies.
- Demonstrated neuroprotective effects in rodent nigrostriatal lesion models.
- White to off-white solid for use in analytical and biological assays.
- High purity (approximately 99.7%) for reproducible experimental results.
- Soluble in DMSO at 100 mg/mL; recommended in vivo formulation protocols available.
- Stable when stored as a powder at -20°C; follow solvent storage guidance for solutions.
- Available as solid and as pre-made DMSO solutions for convenient dosing.
Medchemexpress LLC Glimepiride | 93479-97-1 | 99.9% | C24H34N4O5S | 10 MM * 1 ML
Glimepiride is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg. It is for research use only. It has been shown to decrease extracellular Aβ40 and Aβ42 levels, potentially serving as a promising drug for the treatment of AD associated with diabetes. Compared to other sulfonylureas, it is generally associated with a lower risk of hypoglycemia and less weight gain, and may be safer for patients with cardiovascular disease due to its lack of detrimental effects on ischemic preconditioning.
- Medium-to-long acting sulfonylurea anti-diabetic compound
- Lowers blood glucose in rabbits more effectively than glibenclamide
- Associated with lower risk of hypoglycemia and less weight gain
- May be safer for patients with cardiovascular disease
eMolecules 1314594-23-4 | Medchem Express | PKR-IN-C51 | 5mg | 719835740 | HY-118131 | 367.456 | C23H21N5
Ambeed | 5-Chloro-2-cyano-3-methylpyridine | 1g | 525233235 | A681695 | 156072-84-3 | MFCD17214209 | 152.580 | C7H5ClN2
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Medchemexpress LLC HY-103000 10mg Medchemexpress, HSF1A CAS:1196723-93-9 Purity:>98%
Medchemexpress, HY-103000 10mg HSF1A CAS:1196723-93-9 HSF1A is a cell-permeable activator of heat shock transcription factor 1 (HSF1). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Gliclazide-d4 | 1185039-30-8 | 99.9% | 5 MG
Gliclazide-d4 is the deuterium-labeled form of Gliclazide, an antidiabetic agent that functions as a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Deuteration, the process of incorporating stable heavy isotopes like hydrogen and carbon into drug molecules, is used for quantitation during drug development and has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules.
- Largely used as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC IACS-13909 | 2160546-07-4 | 99.97% | 377.27 | 50 MG
IACS-13909 is a selective, potent, and orally active allosteric inhibitor of SHP2. It demonstrates an IC50 of 15.7 nM and a Kd of 32 nM, exhibiting higher selectivity for SHP2 compared to other phosphatases, including SHP1. This compound possesses antitumor activities and effectively suppresses MAPK pathway signaling in cancers that are dependent on receptor tyrosine kinases (RTK).
- Selective, potent, and orally active SHP2 allosteric inhibitor
- IC50 of 15.7 nM and Kd of 32 nM
- Higher selectivity for SHP2 over other phosphatases
- Exhibits antitumor activities
- Suppresses MAPK pathway signaling in RTK-dependent cancers
- For research use only
Medchemexpress LLC Glimepiride (Standard) | 93479-97-1 | >99.9% | C24H34N4O5S | 100 MG
Glimepiride (Standard) is an analytical standard of Glimepiride, a medium-to-long acting sulfonylurea anti-diabetic compound. It is intended for research and analytical applications, and is not for patient use.
- Medium-to-long acting sulfonylurea anti-diabetic compound
- Lowers blood glucose
- Attenuates Aβ production by suppressing BACE1 activity
- Associated with lower risk of hypoglycemia
- Less weight gain compared to other sulfonylureas
- May be safer for patients with cardiovascular disease