Benzenesulfonamides
eMolecules 342404-46-0 | 1-(Phenylsulfonyl)indole-2-boronic acid | Combi-Blocks | MFCD03086094 | 301.120 | C14H12BNO4S | 96.000 | OB(O)c1cc2ccccc2n1S(=O)(=O)c1ccccc1 | 1g | 117525753
1-(Phenylsulfonyl)indole-2-boronic acid | Combi-Blocks | 342404-46-0 | MFCD03086094 | 301.120 | C14H12BNO4S | 96.000 | OB(O)c1cc2ccccc2n1S(=O)(=O)c1ccccc1 | 1g | 117525753
Medchemexpress LLC Sulfacetamide sodium | 127-56-0 | 99.7% | 1 ML
Sulfacetamide sodium is a sulfonamide antibiotic used for the study of ocular infections. It exhibits antifungal and antibacterial activities. It can be used for the study of various ocular infections like trachoma, blepharitis, conjunctivitis, corneal ulcer, pityriasis versicolor, and rosacea, acting as an antifungal agent through a CYP51A1-independent mechanism and as a bacteriostatic agent with similar activity against both Gram-positive and Gram-negative bacteria.
- Sulfonamide antibiotic
- Antifungal and antibacterial activities
- Effective against various ocular infections including trachoma, blepharitis, conjunctivitis, corneal ulcer, pityriasis versicolor, and rosacea
- Antifungal action through a CYP51A1-independent mechanism
- Bacteriostatic agent against Gram-positive and Gram-negative bacteria
Apexbio Technology LLC Bosentan 147536-97-8 10mM (in 1mL DMSO)
Bosentan (CAS 147536-97-8) is a small molecule that acts as a competitive antagonist at both endothelin-A (ET-A) and endothelin-B (ET-B) receptors By blocking the binding of endothelin-1 to these receptors bosentan modulates endothelin-mediated vasoconstriction and cellular proliferation pathways This compound is utilized in biomedical research to investigate the endothelin signaling axis and its role in cardiovascular physiology pulmonary hypertension and related pathologies Bosentan enables the study of receptor-specific effects of endothelin-1 inhibition and offers a tool for evaluating therapeutic strategies targeting the endothelin system
Medchemexpress LLC HY-15517A 5mg Medchemexpress, KN-92 (phosphate) CAS:1135280-28-2 Purity:>98%
Medchemexpress, HY-15517A 5mg KN-92 (phosphate) CAS:1135280-28-2 0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HMN-176 | 173529-10-7 | MFCD00945108 | 99.4% | 382.43 | 100 MG
HMN-176 is a stilbene derivative that inhibits mitosis by interfering with polo-like kinase-1 (PLK1), without significantly affecting tubulin polymerization. It is intended for research use only and is not sold to patients.
- Inhibits mitosis by interfering with polo-like kinase-1 (PLK1).
- Does not significantly affect tubulin polymerization.
- Increases mitosis duration in hTERT-RPE1 and CFPAC-1 cell lines (at 2.5 μM).
- Inhibits aster formation in a concentration-dependent manner.
- Demonstrates inhibitory effects in multiple tumors (breast, non-small-cell lung, ovarian).
- Shows potent cytotoxicity (mean IC50 of 118 nM).
- Suppresses MDR1 mRNA expression by 56% (at 3 μM).
eMolecules 133745-75-2 | N-Fluorobenzenesulfonimide | Ambeed | MFCD00144885 | 315.330 | C12H10FNO4S2 | 98.000 | FN(S(=O)(=O)c1ccccc1)S(=O)(=O)c1ccccc1 | 10g | 490562797
N-Fluorobenzenesulfonimide | Ambeed | 133745-75-2 | MFCD00144885 | 315.330 | C12H10FNO4S2 | 98.000 | FN(S(=O)(=O)c1ccccc1)S(=O)(=O)c1ccccc1 | 10g | 490562797
Medchemexpress LLC Bosentan | 147536-97-8 | 99.9% | C27H29N5O6S | 100 MG
Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors. It features a high purity of 99.9% and is used in various research applications. It is supplied as a solid.
- Competitive and dual antagonist of endothelin-1 (ET)
- Targets ETA and ETB receptors
- Ki values of 4.7 nM and 95 nM in human SMC for ETA and ETB receptors
- Soluble in DMSO
Medchemexpress LLC HY-10341 500mg , Fasudil (Hydrochloride) HA-1077;AT-877;Fasudil HCl CAS:105628-07-7 Purity:98%
Medchemexpress, HY-10341 500mg Fasudil (Hydrochloride) HA-1077;AT-877;Fasudil HCl CAS:105628-07-7 Formula:C14H18ClN3O2S Ki: 0.33 μM (ROCK1), 1.0 μM (PKA), 9.3 μM (PKC), 55 μM (MLCK) [8] Purity:98% Fasudil Hydrochloride is a potent inhibitor of ROCK1 , PKA , PKC , and MLCK with K i of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
