Benzenesulfonamides
Accela Chembio Inc 4-(difluoromethoxy)benzenesulfonamide | 1g | 874781-09-6 | MFCD03407973 | 95+% | Shelf Life: 1260 Days | Light Sensitive
4-(difluoromethoxy)benzenesulfonamide | 1g | 874781-09-6 | MFCD03407973 | 95+% | Shelf Life: 1260 Days | Light Sensitive
Medchemexpress LLC tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate | 6926-09-6 | MFCD01570558 | 95.0% | 189.21 | 100 G
tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate is a Glycine derivative. Amino acids and amino acid derivatives have been commercially used as ergogenic supplements and are recognized to be beneficial as ergogenic dietary substances.
- Influence the secretion of anabolic hormones
- Supply of fuel during exercise
- Mental performance during stress-related tasks
- Prevent exercise-induced muscle damage
Medchemexpress LLC HY-110195 10mg Medchemexpress, Smurf1-IN-A01 CAS:1007647-73-5 Purity:>98%
Medchemexpress, HY-110195 10mg Smurf1-IN-A01 CAS:1007647-73-5 Smurf1-IN-A01 (A01) is an ubiquitin ligase Smad ubiquitination regulatory factor-1 (Smurf1) inhibitor with a kd of 3.664 nM, which increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC PHT-7.3 | 1614225-93-2 | 99.3% | 10 MG
PHT-7.3 is a selective inhibitor of the connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain, with a Kd of 4.7 μM. It inhibits mutant KRas cancer cell and tumor growth and signaling, without affecting wild-type KRas. PHT-7.3 demonstrates antitumor activity and has shown cytostatic effects in mut-KRas(G12S) A549 and mut-KRasG12V H441 xenograft models at a dosage of 200 mg/kg.
- Selective inhibitor of Cnk1 PH-domain
- Inhibits mutant KRas cancer cell and tumor growth
- Demonstrates antitumor activity
- Shows cytostatic antitumor activity in mut-KRas xenograft models
Chemscene ChemScene | 3-(Trifluoromethyl)benzenesulfonamide | 25G | CS-W013044 | 0.98 | 672-58-2| MFCD00042421 | 225.19
ChemScene | 3-(Trifluoromethyl)benzenesulfonamide | 25G | CS-W013044 | 0.98 | 672-58-2| MFCD00042421 | 225.19
Medchemexpress LLC Pci-27483 | 871266-63-6 | 99.10% | 596.57 | 100 MG
Pci-27483 | 871266-63-6 | 99.10% | 596.57 | 100 MG
eMolecules 1-(2-Nitro-benzenesulfonyl)-piperazine | 301331-16-8 | MFCD00227564 | 5g
J & W PharmLab, LLC | 1-(2-Nitro-benzenesulfonyl)-piperazine | 5g | 249987175 | 65R0139 | 97.000 | 301331-16-8 | MFCD00227564 | 271.290 | C10H13N3O4S
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Apexbio Technology LLC Sildenafil mesylate 1308285-21-3 500mg
Sildenafil mesylate (CAS 1308285-21-3) is a potent and selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) exhibiting an IC50 of 3 5 nM By inhibiting PDE5-mediated cGMP hydrolysis it enhances endogenous cGMP levels particularly within corpus cavernosum tissue In vitro sildenafil mesylate reversibly potentiates relaxation responses in precontracted corpus cavernosum strips following sodium nitroprusside exposure or electrical stimulation and increases intracellular cGMP in treated smooth muscle cells In vivo it augments erectile responses in anesthetized canine models This compound is widely used for studying PDE5-related signaling pathways and pharmacological modulation in erectile and vascular function research
eMolecules Medchem Express / MX69 / 5mg / 446256267 / HY-100892 / / 1005264-47-0 / MFCD24858136 / 474.580 / C27H26N2O4S
Medchem Express / MX69 / 5mg / 446256267 / HY-100892 / / 1005264-47-0 / MFCD24858136 / 474.580 / C27H26N2O4S
Medchemexpress LLC Sildenafil | 139755-83-2 | MFCD00951165 | C22H30N6O4S | 500 MG
Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. It is intended for research use only.
- Potent phosphodiesterase type 5 (PDE5) inhibitor.
- Exhibits an IC50 of 5.22 nM for PDE5.
- Potentiates the phosphorylation of ERK1/ERK2 and increases cell proliferation in vitro.
- Increases intracavernosal pressure (ICP) and ICP/blood pressure (BP) in dog models without significant effects on BP.
- Decreases the number of TL+-cells and reduces microglia/macrophages in certain in vivo models.
- Decreases flap necrosis in preclinical animal models by increasing growth factors (FGF and VEGF).
- Effective in rat cavernous nerve architecture.
- Available in various quantities and forms, including solid and solution in DMSO.
Medchemexpress LLC Sildenafil citrate | 171599-83-0 | MFCD09026931 | C22H30N6O4S ·C6H8O7 | 500 MG
Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. It has demonstrated efficacy in potentiating the phosphorylation of ERK1/ERK2, promoting cell proliferation, and enhancing the upregulation of ERK1/ERK2 phosphorylation induced by serotonin in in vitro studies. In vivo, Sildenafil citrate has been shown to significantly increase intracavernosal pressure (ICP) and ICP/blood pressure (BP) in dog models of erection, and it has been reported to decrease flap necrosis in preclinical animal models.
- Potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM
- Potentiates ERK1/ERK2 phosphorylation in vitro
- Promotes cell proliferation and enhances ERK1/ERK2 phosphorylation induced by serotonin
- Increases intracavernosal pressure (ICP) and ICP/BP in dog models of erection
- Reported to decrease flap necrosis in preclinical animal models
Medchemexpress LLC Sildenafil (citrate) | 171599-83-0 | C28H38N6O11S | 5 G
Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. It is intended for research use only.
- Potent phosphodiesterase type 5 (PDE5) inhibitor with IC50 of 5.22 nM.
- Potentiates phosphorylation of ERK1/ERK2.
- Increases percentage of cells in S phase and cell proliferation.
- Enhances upregulation of ERK1/ERK2 phosphorylation induced by serotonin.
- Increases intracavernosal pressure (ICP) and ICP/BP in dog models.
- Reduces the number of TL+-cells and microglia/macrophages in ischemic models.
- Decreases flap necrosis by increasing growth factors (FGF and VEGF).
- Used in clinical trials for pulmonary arterial hypertension, erectile dysfunction, spinal cord injuries, pregnancy complication, cancer, and more.
Medchemexpress LLC N-Benzyl-N-Cbz-glycine | 76315-01-0 | 265.31 | 1 G
N-Benzyl-N-Cbz-glycine is a derivative of Glycine, appearing as a white to off-white solid. This amino acid derivative is used as an ergogenic supplement, known to influence anabolic hormone secretion, provide fuel during exercise, enhance mental performance during stress, and help prevent exercise-induced muscle damage. It is recognized as a beneficial dietary substance for research use only.
- Derivative of glycine
- Used as an ergogenic supplement
- Influences anabolic hormone secretion
- Supplies fuel during exercise
- Improves mental performance during stress-related tasks
- Prevents exercise-induced muscle damage
- White to off-white solid appearance
- For research use only
![Medchemexpress LLC 5-(2-ethoxy-5-piperazin-1-ylsulfonylphenyl)-1-methyl-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-7-one | 139755-82-1 | MFCD00908398 | 99.5% | 460.55 | C21H28N6O4S | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000227669.png-250.jpg)
Medchemexpress LLC 5-(2-ethoxy-5-piperazin-1-ylsulfonylphenyl)-1-methyl-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-7-one | 139755-82-1 | MFCD00908398 | 99.5% | 460.55 | C21H28N6O4S | 5 MG
N-Desmethyl sildenafil is the primary N-desmethyl metabolite of sildenafil and is provided as a high-purity analytical standard for research, pharmacokinetic, and method development applications. It is a solid white to off-white compound with confirmed molecular formula C21H28N6O4S and a molecular weight of approximately 460.6 g/mol.
- Major metabolite of sildenafil for metabolism studies.
- High purity suitable for analytical and quantitative assays.
- Available in small solid packages and as a solution for analytical use.
- White to off-white solid with consistent lot-specific certificate of analysis.
- Recommended storage at low temperatures for long-term stability.
- Used in pharmacology and method validation workflows.