Benzenesulfonamides
Medchemexpress LLC Glimepiride (Standard) | 93479-97-1 | 99.9% | C24H34N4O5S | 25 MG
Glimepiride (Standard) is an analytical standard, intended for research and analytical applications. It is a medium-to-long acting sulfonylurea anti-diabetic compound that has shown potential in decreasing extracellular Aβ40 and Aβ42 levels, suggesting its use in treating Alzheimer's Disease associated with diabetes. This compound is associated with a lower risk of hypoglycemia and less weight gain compared to other sulfonylureas.
- Analytical standard for research and analytical applications
- Medium-to-long acting sulfonylurea anti-diabetic compound
- Associated with lower risk of hypoglycemia
- Reduced weight gain compared to other sulfonylureas
- May be safer for patients with cardiovascular disease
- Potential to decrease extracellular Aβ40 and Aβ42 levels
Medchemexpress LLC HY-103000 10mg Medchemexpress, HSF1A CAS:1196723-93-9 Purity:>98%
Medchemexpress, HY-103000 10mg HSF1A CAS:1196723-93-9 HSF1A is a cell-permeable activator of heat shock transcription factor 1 (HSF1). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Bosentan Hydrate 157212-55-0 50mg
Bosentan Hydrate (CAS 157212-55-0) is a sulfonamide-derived competitive antagonist of endothelin receptors exhibiting preferential affinity toward endothelin A over endothelin B receptors By interfering with endothelin-triggered signaling in endothelial and vascular smooth muscle cells it attenuates vasoconstrictive and bronchoconstrictive responses In vitro studies revealed bosentan inhibited endothelin receptor activity in P388/dx cells (IC50 15 1 1 6 M) and effectively reversed antiangiogenic effects of systemic sclerosis patient sera on dermal microvascular endothelial cells In animal models bosentan administration post-myocardial infarction significantly elevated plasma leptin levels Clinically bosentan is applied extensively in research on pulmonary arterial hypertension showing beneficial outcomes on patients exercise capacity
Medchemexpress LLC Glimepiride (Standard) | 93479-97-1 | >99.9% | C24H34N4O5S | 100 MG
Glimepiride (Standard) is an analytical standard of Glimepiride, a medium-to-long acting sulfonylurea anti-diabetic compound. It is intended for research and analytical applications, and is not for patient use.
- Medium-to-long acting sulfonylurea anti-diabetic compound
- Lowers blood glucose
- Attenuates Aβ production by suppressing BACE1 activity
- Associated with lower risk of hypoglycemia
- Less weight gain compared to other sulfonylureas
- May be safer for patients with cardiovascular disease
Medchemexpress LLC HY-B0375A 10mg Medchemexpress, Argatroban (monohydrate) CAS:141396-28-3 Purity:>98%
Medchemexpress, HY-B0375A 10mg Argatroban (monohydrate) CAS:141396-28-3 Argatroban (monohydrate) (MD-805 (monohydrate)) is a direct, selective thrombin inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC N-desmethyl sildenafil-d8 | 1185168-06-2 | 99.3% | 468.60 | C21H20D8N6O4S | 1 MG
N-Desmethyl Sildenafil-d8 is the deuterium-labeled form of N-desmethyl sildenafil supplied as a high-purity analytical standard for LC-MS/MS, pharmacokinetic, and metabolic studies. It provides a stable isotope internal standard for accurate quantitation and method development.
- Deuterium-labeled internal standard for mass spectrometry
- High purity (99.3%) for reliable quantitation
- Molecular formula C21H20D8N6O4S; molecular weight 468.60
- Available in small quantities suitable for analytical use (1 mg, 5 mg)
- Stable isotope reduces matrix effects and improves accuracy
Medchemexpress LLC HY-10858 5mg Medchemexpress, WAY 316606 CAS:915759-45-4 Purity:>98%
Medchemexpress, HY-10858 5mg WAY 316606 CAS:915759-45-4 WAY 316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. The affinity of WAY-316606 for sFRP-1 is determined using the FP binding assay with IC50 of 0.5 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 862189-96-6 | Medchem Express | Mirodenafil (dihydrochloride) | 5mg | 446264794 | HY-14930A | MFCD28139019 | 604.59 | C26H39Cl2N5O5S
Medchem Express | Mirodenafil (dihydrochloride) | 5mg | 446264794 | HY-14930A | 862189-96-6 | MFCD28139019 | 604.590 | C26H39Cl2N5O5S
Medchemexpress LLC HY-110195 10mg Medchemexpress, Smurf1-IN-A01 CAS:1007647-73-5 Purity:>98%
Medchemexpress, HY-110195 10mg Smurf1-IN-A01 CAS:1007647-73-5 Smurf1-IN-A01 (A01) is an ubiquitin ligase Smad ubiquitination regulatory factor-1 (Smurf1) inhibitor with a kd of 3.664 nM, which increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Sulfasalazine 10mM/1mL 599-79-1 Azulfidine, Salazopyrin, Sulphasalazine
Sulfasalazine (Azulfidine, Salazopyrin, Sulphasalazine) is a sulfa derivative of mesalazine, used as an anti-inflammatory agent to treat bowel disease and rheumatoid arthritis. Sulfasalazine is a potent and specific inhibitor of nuclear factor kappa B (NF-?B), TGF-? and COX-2. Sulfasalazine induces ferroptosis, apoptosis and autophagy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
![Medchemexpress LLC 4-[[4-(2-butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide | 287403-39-8 | 99.6% | 398.50 g/mol | C17H22N2O5S2 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000248736.png-250.jpg)
Medchemexpress LLC 4-[[4-(2-butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide | 287403-39-8 | 99.6% | 398.50 g/mol | C17H22N2O5S2 | 100 MG
TMI-1 (WAY-171318) is a small-molecule inhibitor of TNF-α converting enzyme (TACE) with reported activity against ADAM-17, ADAMTS-4, and multiple MMPs. Supplied for research use, it has demonstrated oral activity and induces apoptosis in cancer cell models, and is provided with analytical documentation for laboratory studies.
- Purity 99.57%.
- Molecular formula C17H22N2O5S2.
- Molecular weight 398.50 g/mol.
- Available as solid (5 mg, 10 mg, 25 mg, 50 mg, 100 mg) and solution (10 mM in DMSO).
- Includes datasheet, COA, and SDS documentation.
- Suitable for biochemical, cell-based, and in vivo oral dosing research (research use only).
Medchemexpress LLC HY-15833 50mg , Chlorthalidone CAS:77-36-1 Purity:98%
Medchemexpress, HY-15833 50mg Chlorthalidone CAS:77-36-1 Formula:C14H11ClN2O4S Purity:98% Chlorthalidone is a thiazide-like diuretic used to treat hypertension. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![eMolecules 31696-45-4 | Ethyl 3-[(phenylsulfonyl)oxy]-5-isoxazoleacetate | Synthonix311.310 | C13H13NO6S | 97.000 | CCOC(=O)Cc1cc(OS(=O)(=O)c2ccccc2)no1 | 10mg | 786491789](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502456934.PNG-250.jpg)
eMolecules 31696-45-4 | Ethyl 3-[(phenylsulfonyl)oxy]-5-isoxazoleacetate | Synthonix311.310 | C13H13NO6S | 97.000 | CCOC(=O)Cc1cc(OS(=O)(=O)c2ccccc2)no1 | 10mg | 786491789
Ethyl 3-[(phenylsulfonyl)oxy]-5-isoxazoleacetate | Synthonix | 31696-45-4311.310 | C13H13NO6S | 97.000 | CCOC(=O)Cc1cc(OS(=O)(=O)c2ccccc2)no1 | 10mg | 786491789