CD73-IN-3 is a potent inhibitor of CD73, demonstrating an IC50 of 7.3 nM in a Calu6 human cell assay. This compound, identified as example 2 from patent WO2019168744 A1, holds potential for cancer research. It inhibits CD73 activity in human serum with an EC50 of 0.213 μM. The product is a solid, white to off-white in color.
- Potent inhibitor of CD73
- IC50 of 7.3 nM in Calu6 human cell assay
- Inhibits CD73 activity in human serum with an EC50 of 0.213 μM
- Potential for cancer research
- Appears as a solid, white to off-white