N-phenylureas
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Filtered Search Results
Medchemexpress LLC Urea, N-(2-bromophenyl)-N'-[2-[ethyl(3-methylphenyl)amino]ethyl]- | 459429-39-1 | 99.1% | 376.29 | 100 MG
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SB 452533 is a potent and selective TRPV1 antagonist with a pKb of 7.8. It is intended for research use only.
- Acts as a potent antagonist at the cloned recombinant rat TRPV1 receptor in HEK293 cells, with a pKb of 7.7 and a pIC50 of 7.0.
- Reduces the phosphorylation of CAMKK2 and AMPK in skeletal muscle (C2C12) cells.
- Abolishes Capsaicin's effect of reducing Bleomycin-induced pulmonary fibrosis in BALB/c mice.
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AMBEED 1 4 FLUOROPHENYL CYCLOBUTANECA
NC2790813 1 4 FLUOROPHENYL CYCLOBUTANECA
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AA BLOCKS LLC
NC4037976 2 BROMO 6 FLUOROPHENYL BIS 2
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Aobchem 1 3-Bis(3 4-difluorophenyl)urea | 95% | CAS 218135-47-8 | C13H8F4N2O | 5g
1 3-Bis(3 4-difluorophenyl)urea | 95% | CAS 218135-47-8 | C13H8F4N2O | 5g
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Aobchem 1 3-Bis(3 4-difluorophenyl)urea | 95% | CAS 218135-47-8 | C13H8F4N2O | 500mg
1 3-Bis(3 4-difluorophenyl)urea | 95% | CAS 218135-47-8 | C13H8F4N2O | 500mg
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Aobchem 1 3-Bis(3 4-difluorophenyl)urea | 95% | CAS 218135-47-8 | C13H8F4N2O | 1g
1 3-Bis(3 4-difluorophenyl)urea | 95% | CAS 218135-47-8 | C13H8F4N2O | 1g
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Aobchem 1 3-Bis(3 4-difluorophenyl)urea | 95% | CAS 218135-47-8 | C13H8F4N2O | 250mg
1 3-Bis(3 4-difluorophenyl)urea | 95% | CAS 218135-47-8 | C13H8F4N2O | 250mg
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Medchemexpress LLC SB 452533 | 459429-39-1 | 99.1% | 376.29 | 1 ML
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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SB 452533 is a potent and selective TRPV1 antagonist with a pKb of 7.8. It is for research use only and not sold to patients.
- Potent antagonist at the cloned recombinant rat TRPV1 receptor in HEK293 cells.
- Reduces phosphorylation of CAMKK2 and AMPK.
- Abolishes the effects of small dose Capsaicin in reducing Bleomycin-induced pulmonary fibrosis in mice.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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BLD PHARMATECH CO LIMITED 2 4 FLUOROPHENYL 5 METHOXYP 1G
NC3253461 2 4 FLUOROPHENYL 5 METHOXYP 1G
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Medchemexpress LLC SB-265610 | 211096-49-0 | 98.98% | C14H9BrN6O | 50 MG
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SB-265610 is a selective, competitive, nonpeptide, and allosteric CXCR2 antagonist. It blocks rat CINC-1-induced calcium mobilization (IC50 of 3.7 nM) and neutrophil chemotaxis (IC50 of 70 nM). In animal models, it significantly inhibits Gr-1+CD11b+ cell recruitment to mammary adenocarcinoma.
- Selective, competitive, nonpeptide, and allosteric CXCR2 antagonist.
- Blocks rat CINC-1-induced calcium mobilization (IC50 of 3.7 nM).
- Blocks neutrophil chemotaxis (IC50 of 70 nM).
- Reduces CINC-1's antiapoptotic effect.
- Inhibits Gr-1+CD11b+ cell recruitment to mammary adenocarcinoma in animal models.
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Medchemexpress LLC 1-(2-bromophenyl)-3-(7-cyano-2H-benzotriazol-4-yl)urea | 211096-49-0 | MFCD09971124 | 699.0% | 357.16 g·mol⁻¹ | C14H9BrN6O | 10 MG
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SB-265610 is a selective, competitive, nonpeptide, allosteric antagonist of the CXCR2 chemokine receptor used as a research reagent to study neutrophil chemotaxis and CXCR2-mediated signaling. It inhibits CINC-1-induced calcium mobilization (IC50 3.7 nM) and neutrophil chemotaxis (IC50 70 nM).
- Selective CXCR2 antagonist for receptor pharmacology studies.
- Reported low-nanomolar potency for calcium mobilization assays.
- Suitable for in vitro chemotaxis and signaling experiments.
- Supplied as a small-molecule solid for formulation or dosing control.
- Characterized by published analytical data and CAS registration for traceability.
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Medchemexpress LLC SB 452533 | 459429-39-1 | 99.11% | 376.29 | 50 MG
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SB 452533 is a potent and selective TRPV1 antagonist with a pKb of 7.8. It functions by acting as a potent antagonist at the cloned recombinant rat TRPV1 receptor in HEK293 cells. This compound has been shown to reduce phosphorylation of CAMKK2 and AMPK, and to abolish the effects of Capsaicin in reducing Bleomycin-induced pulmonary fibrosis in mice.
- Potent and selective TRPV1 antagonist
- Reduces phosphorylation of CAMKK2 and AMPK
- Abolishes the effects of capsaicin in reducing bleomycin-induced pulmonary fibrosis in mice
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC SB-265610 | 211096-49-0 | ≥99.0% | C14H9BrN6O | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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SB-265610 | 211096-49-0 | ≥99.0% | C14H9BrN6O | 5 MG
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Medchemexpress LLC HY-50688 25mg Medchemexpress, SB-265610 CAS:211096-49-0 Purity:>98%
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Medchemexpress, HY-50688 25mg SB-265610 CAS:211096-49-0 SB-265610 is a selective, competitive, nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis with IC50s of 3.7 nM and 70 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 64-10-8 | N-Phenylurea | Ambeed | MFCD19441482 | 136.154 | C7H8N2O | 98.000 | OC(=N)Nc1ccccc1 | 25g | 523728438
N-Phenylurea | Ambeed | 64-10-8 | MFCD19441482 | 136.154 | C7H8N2O | 98.000 | OC(=N)Nc1ccccc1 | 25g | 523728438
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