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N-phenylureas

Organic compounds that consist of a urea molecule with a phenyl functional group substitution on one of the two nitrogen atoms on the urea molecule.
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46 – 56 of 56 results
46

Medchemexpress LLC SB-265610 | 211096-49-0 | 98.98% | C14H9BrN6O | 50 MG
SDP

SB-265610 is a selective, competitive, nonpeptide, and allosteric CXCR2 antagonist. It blocks rat CINC-1-induced calcium mobilization (IC50 of 3.7 nM) and neutrophil chemotaxis (IC50 of 70 nM). In animal models, it significantly inhibits Gr-1+CD11b+ cell recruitment to mammary adenocarcinoma.

  • Selective, competitive, nonpeptide, and allosteric CXCR2 antagonist.
  • Blocks rat CINC-1-induced calcium mobilization (IC50 of 3.7 nM).
  • Blocks neutrophil chemotaxis (IC50 of 70 nM).
  • Reduces CINC-1's antiapoptotic effect.
  • Inhibits Gr-1+CD11b+ cell recruitment to mammary adenocarcinoma in animal models.

ENCOMPASS_PREFERRED
47

Medchemexpress LLC 1-(2-bromophenyl)-3-(7-cyano-2H-benzotriazol-4-yl)urea | 211096-49-0 | MFCD09971124 | 699.0% | 357.16 g·mol⁻¹ | C14H9BrN6O | 10 MG
SDP

SB-265610 is a selective, competitive, nonpeptide, allosteric antagonist of the CXCR2 chemokine receptor used as a research reagent to study neutrophil chemotaxis and CXCR2-mediated signaling. It inhibits CINC-1-induced calcium mobilization (IC50 3.7 nM) and neutrophil chemotaxis (IC50 70 nM).

  • Selective CXCR2 antagonist for receptor pharmacology studies.
  • Reported low-nanomolar potency for calcium mobilization assays.
  • Suitable for in vitro chemotaxis and signaling experiments.
  • Supplied as a small-molecule solid for formulation or dosing control.
  • Characterized by published analytical data and CAS registration for traceability.

ENCOMPASS_PREFERRED
48

Medchemexpress LLC SB 452533 | 459429-39-1 | 99.1% | 376.29 | 1 ML
SDP

SB 452533 is a potent and selective TRPV1 antagonist with a pKb of 7.8. It is for research use only and not sold to patients.

  • Potent antagonist at the cloned recombinant rat TRPV1 receptor in HEK293 cells.
  • Reduces phosphorylation of CAMKK2 and AMPK.
  • Abolishes the effects of small dose Capsaicin in reducing Bleomycin-induced pulmonary fibrosis in mice.

ENCOMPASS_PREFERRED
49

eMolecules​ AstaTech / (4-FLUOROPHENYL)METHANAMINE HCL / 0.25g / 718060000 / N12249 / 95.000 / 659-41-6 / MFCD00012861 / 161.600 / C7H9ClFN

AstaTech / (4-FLUOROPHENYL)METHANAMINE HCL / 0.25g / 718060000 / N12249 / 95.000 / 659-41-6 / MFCD00012861 / 161.600 / C7H9ClFN

ENCOMPASS_PREFERRED
50

Medchemexpress LLC HY-50688 25mg Medchemexpress, SB-265610 CAS:211096-49-0 Purity:>98%
SDP

Medchemexpress, HY-50688 25mg SB-265610 CAS:211096-49-0 SB-265610 is a selective, competitive, nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis with IC50s of 3.7 nM and 70 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

ENCOMPASS_PREFERRED
51

eMolecules​ Ambeed / 1-Phenylurea / 25g / 523728438 / A107537 / / 64-10-8 / MFCD19441482 / 136.154 / C7H8N2O

Ambeed / 1-Phenylurea / 25g / 523728438 / A107537 / / 64-10-8 / MFCD19441482 / 136.154 / C7H8N2O

ENCOMPASS_PREFERRED
52

(4-Fluorophenyl)urea 97.0+%, TCI America™

CAS: 659-30-3 Molecular Formula: C7H7FN2O Molecular Weight (g/mol): 154.14 MDL Number: MFCD00014787 InChI Key: IQZBVVPYTDHTIP-UHFFFAOYSA-N Synonym: 4-fluorophenyl urea,1-4-fluorophenyl urea,urea, 1-p-fluorophenyl,1-p-fluorophenyl urea,n-4-fluorophenyl urea,p-fluorophenylurea,amino-n-4-fluorophenyl amide,n'-4-fluorophenyl urea PubChem CID: 12612 IUPAC Name: (4-fluorophenyl)urea SMILES: NC(=O)NC1=CC=C(F)C=C1

PubChem CID 12612
CAS 659-30-3
Molecular Weight (g/mol) 154.14
MDL Number MFCD00014787
SMILES NC(=O)NC1=CC=C(F)C=C1
Synonym 4-fluorophenyl urea,1-4-fluorophenyl urea,urea, 1-p-fluorophenyl,1-p-fluorophenyl urea,n-4-fluorophenyl urea,p-fluorophenylurea,amino-n-4-fluorophenyl amide,n'-4-fluorophenyl urea
IUPAC Name (4-fluorophenyl)urea
InChI Key IQZBVVPYTDHTIP-UHFFFAOYSA-N
Molecular Formula C7H7FN2O
53

4,4-Diphenylsemicarbazide 98%, Thermo Scientific™

CAS: 603-51-0 Molecular Formula: C13H13N3O Molecular Weight (g/mol): 227.27 MDL Number: MFCD00007592 InChI Key: VVVFQQJJJRFDTE-UHFFFAOYSA-N Synonym: 4,4-diphenylsemicarbazide,n,n-diphenylhydrazinecarboxamide,hydrazinecarboxamide, n,n-diphenyl,semicarbazide, 4,4-diphenyl,qa7tgp7xir,unii-qa7tgp7xir,hydrazinecarboxamide,n,n-diphenyl,semicarbazide,4-diphenyl,hydrazinecarboxamide,n-diphenyl,4,4-diphenylsemicar-bazide PubChem CID: 69049 IUPAC Name: 3-amino-1,1-diphenylurea SMILES: NNC(=O)N(C1=CC=CC=C1)C1=CC=CC=C1

PubChem CID 69049
CAS 603-51-0
Molecular Weight (g/mol) 227.27
MDL Number MFCD00007592
SMILES NNC(=O)N(C1=CC=CC=C1)C1=CC=CC=C1
Synonym 4,4-diphenylsemicarbazide,n,n-diphenylhydrazinecarboxamide,hydrazinecarboxamide, n,n-diphenyl,semicarbazide, 4,4-diphenyl,qa7tgp7xir,unii-qa7tgp7xir,hydrazinecarboxamide,n,n-diphenyl,semicarbazide,4-diphenyl,hydrazinecarboxamide,n-diphenyl,4,4-diphenylsemicar-bazide
IUPAC Name 3-amino-1,1-diphenylurea
InChI Key VVVFQQJJJRFDTE-UHFFFAOYSA-N
Molecular Formula C13H13N3O
54

1-(2-Chlorophenyl)-3-[4-(trifluoromethoxy)phenyl]urea, 97%, Thermo Scientific™

CAS: 406930-04-9 Molecular Formula: C14H10ClF3N2O2 Molecular Weight (g/mol): 330.691 MDL Number: MFCD02632826 InChI Key: IBVFZYNARZAJSE-UHFFFAOYSA-N Synonym: 1-2-chlorophenyl-3-4-trifluoromethoxy phenyl urea,3-2-chlorophenyl-1-4-trifluoromethoxy phenyl urea,1-2-chlorophenyl-3-4-trifluoromethoxyphenyl urea PubChem CID: 951288 IUPAC Name: 1-(2-chlorophenyl)-3-[4-(trifluoromethoxy)phenyl]urea SMILES: C1=CC=C(C(=C1)NC(=O)NC2=CC=C(C=C2)OC(F)(F)F)Cl

PubChem CID 951288
CAS 406930-04-9
Molecular Weight (g/mol) 330.691
MDL Number MFCD02632826
SMILES C1=CC=C(C(=C1)NC(=O)NC2=CC=C(C=C2)OC(F)(F)F)Cl
Synonym 1-2-chlorophenyl-3-4-trifluoromethoxy phenyl urea,3-2-chlorophenyl-1-4-trifluoromethoxy phenyl urea,1-2-chlorophenyl-3-4-trifluoromethoxyphenyl urea
IUPAC Name 1-(2-chlorophenyl)-3-[4-(trifluoromethoxy)phenyl]urea
InChI Key IBVFZYNARZAJSE-UHFFFAOYSA-N
Molecular Formula C14H10ClF3N2O2
55

SB 228357, Tocris Bioscience™

CAS: 181629-93-6 Molecular Formula: C22H17F4N3O2 Molecular Weight (g/mol): 431.391 InChI Key: RRJLJKRFFRZRAF-UHFFFAOYSA-N Synonym: unii-5rdn2e8e97,tocris-1375,chembl14276,n-3-fluoro-5-3-pyrindyl phenyl-2,3-dihydro-5-methoxy-6-trifluoromethyl-1h-indole-1-carboxamide,n-3-fluoro-5-pyridin-3-ylphenyl-5-methoxy-6-trifluoromethyl-2,3-dihydroindole-1-carboxamide,n-3-fluoro-5-3-pyridinyl phenyl-2,3-dihydro-5-methoxy-6-trifluoromethyl-1h-indole-1-carboxamide,lopac-s-2318,d05nwh,gtpl192,n-3-3-pyridinyl-5-fluorophenyl-5-methoxy-6-trifluoromethyl indoline-1-carboxamide PubChem CID: 443390 ChEBI: CHEBI:8979 IUPAC Name: N-(3-fluoro-5-pyridin-3-ylphenyl)-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide SMILES: COC1=C(C=C2C(=C1)CCN2C(=O)NC3=CC(=CC(=C3)C4=CN=CC=C4)F)C(F)(F)F

PubChem CID 443390
CAS 181629-93-6
Molecular Weight (g/mol) 431.391
ChEBI CHEBI:8979
SMILES COC1=C(C=C2C(=C1)CCN2C(=O)NC3=CC(=CC(=C3)C4=CN=CC=C4)F)C(F)(F)F
Synonym unii-5rdn2e8e97,tocris-1375,chembl14276,n-3-fluoro-5-3-pyrindyl phenyl-2,3-dihydro-5-methoxy-6-trifluoromethyl-1h-indole-1-carboxamide,n-3-fluoro-5-pyridin-3-ylphenyl-5-methoxy-6-trifluoromethyl-2,3-dihydroindole-1-carboxamide,n-3-fluoro-5-3-pyridinyl phenyl-2,3-dihydro-5-methoxy-6-trifluoromethyl-1h-indole-1-carboxamide,lopac-s-2318,d05nwh,gtpl192,n-3-3-pyridinyl-5-fluorophenyl-5-methoxy-6-trifluoromethyl indoline-1-carboxamide
IUPAC Name N-(3-fluoro-5-pyridin-3-ylphenyl)-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
InChI Key RRJLJKRFFRZRAF-UHFFFAOYSA-N
Molecular Formula C22H17F4N3O2
56

Cayman Chemical DOLUTEGRAVIR-5G

NC2854320 DOLUTEGRAVIR-5G

ENCOMPASS_PREFERRED