Phenoxy compounds
Medchemexpress LLC FR194738 | 204067-52-7 | 99.8% | 476.11 | C27H38ClNO2S | 50 MG
FR194738 is a potent squalene epoxidase inhibitor used in biochemical and cell-based research to block cholesterol biosynthesis. It inhibits squalene epoxidase in HepG2 cell homogenates with an IC50 of 9.8 nM and reduces cholesterol formation in intact HepG2 cells (IC50s 4.9 nM and 8.0 nM). Supplied as a solid for research use (CAS 204067-52-7); solubility and storage guidance are provided.
Medchemexpress LLC FR194738 | 204067-52-7 | 99.8% | 476.11 | C27H38ClNO2S | 25 MG
FR194738 is a small-molecule squalene epoxidase inhibitor for preclinical research. It inhibits squalene epoxidase activity in HepG2 cell homogenates (IC50 = 9.8 nM) and is provided with analytical characterization suitable for biochemical and cellular studies.
- Potent squalene epoxidase inhibitor (IC50 = 9.8 nM).
- Suitable for biochemical and cell-based assays.
- High purity appropriate for analytical applications (~99.8%).
- Characterized by CAS number 204067-52-7 and molecular weight 476.11.
- Available in multiple vial sizes, including 25 mg.
- Supplied with supporting documentation: datasheet, COA, SDS, H NMR, LCMS.
eMolecules N-Phenyl 4-fluorobenzenesulfonamide | 312-52-7 | MFCD00447248 | 1g
Combi-Blocks | N-Phenyl 4-fluorobenzenesulfonamide | 1g | 117542994 | OT-0962 | 95.000 | 312-52-7 | MFCD00447248 | 251.280 | C12H10FNO2S
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eMolecules Medchem Express / PF-4800567 / 5mg / 437899366 / HY-12470 / / 1188296-52-7 / MFCD22123245 / 359.810 / C17H18ClN5O2
Medchem Express / PF-4800567 / 5mg / 437899366 / HY-12470 / / 1188296-52-7 / MFCD22123245 / 359.810 / C17H18ClN5O2
Medchemexpress LLC E-N-ethyl-N-(6,6-dimethyl-2-hepten-4-ynyl)-3-(2-methyl-2-(3-thienylmethoxy)propyloxy)benzylamine HCl | 204067-52-7 | 98.8% | 476.11 | C27H38ClNO2S | 100 MG
FR194738 is a research compound that potently inhibits squalene epoxidase and is used to investigate cholesterol biosynthesis in biochemical and cell-based assays. Reported activity includes an IC50 of 9.8 nM in HepG2 cell homogenates and 4.9 nM for inhibition of cholesterol synthesis in intact HepG2 cells. Supplied as a high-purity free base with multiple package sizes and storage recommendations for laboratory use.
- Potent squalene epoxidase inhibition in biochemical and cell assays.
- Demonstrated low-nanomolar IC50 in HepG2 assays.
- Available as a free base with supplier-reported high purity.
- Multiple package sizes for flexible experimental scaling.
- Storage recommendations support compound stability for routine use.
- For research use only; not for human or clinical use.