Phenoxy compounds
Medchemexpress LLC HG-7-85-01-NH2 | 1258391-29-5 | 98.1% | 50 MG
HG-7-85-01-NH2 is a small-molecule ligand derived from an ABL inhibitor. It serves as a target protein ligand for synthesizing the heterobifunctional molecule SNIPER and can bind to an IAP ligand via a linker to form SNIPER(ABL)-033. The resulting SNIPER(ABL)-033 effectively degrades BCR-ABL protein.
- Derived from an ABL inhibitor.
- Functions as a target protein ligand for SNIPER synthesis.
- Forms a heterobifunctional molecule when linked to an IAP ligand.
- Used in the formation of SNIPER(ABL)-033, which degrades BCR-ABL protein.
- Intended for research use only.
Medchemexpress LLC Hg-7-85-01-nh2 | 1258391-29-5 | 98.1% | 540.60 | C27H27F3N6OS | 5 MG
HG-7-85-01-NH2 is a small-molecule ligand derived from an ABL inhibitor, designed for use as the target-protein binding moiety in heterobifunctional degraders such as SNIPERs and PROTACs. Supplied as a high-purity solid, the compound includes clear solubility and storage recommendations appropriate for research applications; not for human use.
- High purity solid suitable for research.
- Soluble in DMSO at high concentration (125 mg/mL) with pH adjustment guidance.
- Provides a binding moiety for Bcr-Abl-targeting degraders.
- Specified storage conditions for powder and in solvent to maintain stability.
- Intended for research use only.
eMolecules Medchem Express / UNC0638 / 5mg / 446265321 / HY-15273 / / 1255580-76-7 / MFCD22208587 / 509.739 / C30H47N5O2
Medchem Express / UNC0638 / 5mg / 446265321 / HY-15273 / / 1255580-76-7 / MFCD22208587 / 509.739 / C30H47N5O2
Medchemexpress LLC HG-7-85-01-NH2 | 1258391-29-5 | MFCD34646287 | 98.1% | C27H27F3N6OS | 10MG
HG-7-85-01-NH2 is a research ligand derived from the ABL inhibitor HG-7-85-01, designed to act as the target-protein-binding moiety in SNIPER constructs for targeted protein degradation studies. It is supplied as a characterized, high-purity compound with manufacturer-recommended solubility and storage conditions for preclinical research use.
- High purity (98.1%).
- Molecular formula C27H27F3N6OS; molecular weight 540.6.
- Soluble in DMSO at 125 mg/mL (231.22 mM) with ultrasonic aid and pH adjustment.
- Powder stable at -20°C for up to 3 years; in solvent stable at -80°C for 6 months.
- Supplied in multiple small research quantities.
- Intended for synthesis of SNIPER molecules and targeted degradation assays.