Phenoxy compounds

IMAGION BIOSYSTEMS INC PrecisionMRX mPEG Coated Iron Oxide Nanoparticles-10mg

Superparamagnetic iron oxide nanoparticles with a core diameter of 24 – 26 nm and a low size dispersity (≤7%) as measured by Small Angle X-ray Scattering (SAXS). The cores are coated with a monolayer of oleic acid, a monolayer of an amphiphilic polymer, and a monolayer of methoxypolyethylene glycol (mPEG).

IMAGION BIOSYSTEMS INC PrecisionMRX Carboxylic Acid Functionalized Iron Oxide Nanoparticles -50mg

Water soluble, superparamagnetic iron oxide nanoparticles with a core diameter of 24 – 26 nm and a low size dispersity (≤7%) as measured by Small Angle X-ray Scattering (SAXS). Nanoparticle cores are coated with a monolayer of oleic acid and a monolayer of an amphiphilic polymer with carboxylic acid functional groups displayed on the surface. Carboxylic acid functionality allows conjugation to molecules containing amine groups, such as proteins and peptides. The hydrodynamic diameter of the particles is approximately 30 nm larger than the core size measured by SAXS, and their zeta potential ranges from -60 to -70 mV. These particles are stable in most buffer solutions in the range of pH 4 – 10.

IMAGION BIOSYSTEMS INC PrecisionMRX Carboxylic Acid Functionalized Iron Oxide Nanoparticles -10mg

Water soluble, superparamagnetic iron oxide nanoparticles with a core diameter of 24 – 26 nm and a low size dispersity (≤7%) as measured by Small Angle X-ray Scattering (SAXS). Nanoparticle cores are coated with a monolayer of oleic acid and a monolayer of an amphiphilic polymer with carboxylic acid functional groups displayed on the surface. Carboxylic acid functionality allows conjugation to molecules containing amine groups, such as proteins and peptides. The hydrodynamic diameter of the particles is approximately 30 nm larger than the core size measured by SAXS, and their zeta potential ranges from -60 to -70 mV. These particles are stable in most buffer solutions in the range of pH 4 – 10.

Medchemexpress LLC 2-pyridin-2-yl-4,5-dihydro-3H-benzo[e]indazol-1-one | 1062648-63-8 | 99.9% | 263.29 g/mol | C16H13N3O | 5MG

DMT1 blocker 2 (2-pyridin-2-yl-4,5-dihydro-3H-benzo[e]indazol-1-one) is a small-molecule research compound that directly inhibits divalent metal transporter 1 (DMT1) with an in vitro IC50 of 0.83 μM. It blocks iron uptake by enterocytes in vivo and is supplied as a high-purity solid suitable for biochemical and cellular studies.

• Direct DMT1 inhibitor, IC50 = 0.83 μM.
• High purity (99.9%).
• Molecular formula C16H13N3O; molecular weight 263.29 g/mol.
• Soluble in DMSO for stock solution preparation.
• Suitable for biochemical assays and cellular studies of iron transport.

Selleck Chemical LLC Pioglitazone HCl S2046-200mg

Pioglitazone HCl (AD-4833 U-72107E) is an inhibitor of cytochrome P450 (CYP)2C8 and CYP3A4 enzymes Pioglitazone HCl inhibits CYP2C8 CYP3A4 and CYP2C9 with Ki of 1 7 M 11 8 M and 32 1 M respectively Pioglitazone HCl is also a selective peroxisome proliferator-activated receptor-gamma (PPAR ) agonist with EC50 of 0 93 M and 0 99 M for human PPAR and mouse PPAR respectively Pioglitazone HCl inhibits mitochondrial iron uptake lipid peroxidation and subsequent ferroptosis