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AP1867-2-(carboxymethoxy) is an AP1867-derived FKBP12-binding building block used in targeted protein degradation chemistry. It functions as a linker-compatible moiety for constructing PROTAC and dTAG molecules and is provided as a high-purity research reagent for medicinal chemistry and chemical biology applications.
High purity suitable for research applications.
Designed for FKBP12-directed binding in degrader constructs.
Compatible with common linker chemistries for conjugation.
Available in multiple milligram-scale pack sizes for synthesis.
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AP1867-2-(carboxymethoxy) is a synthetic FKBP12F36V-directed ligand fragment used as the FKBP12-binding moiety in dTAG/PROTAC constructs for targeted protein degradation research.
Used to link FKBP12F36V to a CRBN ligand for dTAG-mediated degradation.
High purity suitable for research (HPLC purity reported as 99.88%).
Available as solid and as a DMSO solution for convenient formulation.
Offered in multiple pack sizes to support screening and scale-up.
Soluble in DMSO for solution preparation.
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AP1867-2-(carboxymethoxy) is a PROTAC FKBP12-binding moiety based on the synthetic FKBP12F36V-directed ligand AP1867, intended for research use in assembling dTAG molecules that engage FKBP12F36V and CRBN in vitro.
High purity for reliable assay results.
Molecular weight 693.78 g/mol.
Chemical formula C38H47NO11.
Designed to link to CRBN ligands to form dTAG molecules.
Available in multiple pack sizes for assay development.
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