Phenylhydrazines
Medchemexpress LLC Triprolidine (hydrochloride) | 550-70-9 | 25MG
Triprolidine hydrochloride is an orally active histamine H1 antagonist. It has the function of spinal cord motor and sensory block and can be used for the research of allergic rhinitis.
- Orally active histamine H1 antagonist.
- Exhibits spinal cord motor and sensory block function.
- Can antagonize histamine H1 and decrease the expression of CD45 in maturing human dendritic cells.
- Produces a dose-dependent effect of spinal motor and sensory block in rats when administered intrathecally.
eMolecules 80567-00-6 | 2,6-Dimethylmorpholine hydrochloride | MFCD28099212 | 25g
Ambeed | 2,6-Dimethylmorpholine hydrochloride | 25g | 600843443 | A576751 | 80567-00-6 | MFCD28099212 | 151.630 | C6H14ClNO
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Medchemexpress LLC Tetracycline hydrochloride | 64-75-5 | 98.7% | 100 MG
Tetracycline hydrochloride | 64-75-5 | 98.7% | 100 MG
Medchemexpress LLC JH-X-119-01 hydrochloride | 2591344-30-6 | 99.1% | 488.93 | 10 MG
JH-X-119-01 hydrochloride is a potent and selective interleukin-1 receptor-associated kinases 1 (IRAK1) inhibitor. It ameliorates LPS-induced sepsis in mice by decreasing phosphorylation of NF-κB and mRNA levels of IL-6 and TNFα in LPS-treated macrophages in vitro. It selectively inhibits IRAK1 phosphorylation. In vivo, it improves survival and decreases immunopathies of LPS-challenged mice, increasing survival at doses of 5 mg/kg and 10 mg/kg body weight.
- Potent and selective IRAK1 inhibitor
- Ameliorates LPS-induced sepsis in mice
- Decreases phosphorylation of NF-κB and mRNA levels of IL-6 and TNFα in LPS-treated macrophages in vitro
- Selectively inhibits IRAK1 phosphorylation
- Improves survival and decreases immunopathies in LPS-challenged mice
- For research use only
Medchemexpress LLC Medetomidine (hydrochloride) | 86347-15-1 | 99.8% | 236.74 | 5 MG
Medetomidine hydrochloride from MedChemExpress is provided for laboratory chemical applications and substance manufacturing. This product is a white to off-white solid.
- Suitable for laboratory chemicals and substance manufacturing
- White to off-white solid appearance
- Store at 4°C, sealed and away from moisture
- Purity of 99.8% confirmed by LCMS
- For research use only; not validated for medical applications
Medchemexpress LLC Methoxyamine hydrochloride | 593-56-6 | MFCD00012951 | 98.0% | 83.52 g/mol | CH5NO·HCl | 5g
Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor Methoxyamine hydrochloride binds to 3 hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents[1][2]
Medchemexpress LLC Sucunamostat (hydrochloride) | 00-00-0 | 98.1% | C22H23ClN4O8 | 10MG
Sucunamostat hydrochloride is an orally active, reversible enteropeptidase inhibitor used in biochemical and pharmacological research to investigate protein digestion and related metabolic pathways. It is supplied as a hydrochloride salt for consistent handling and formulation in laboratory studies.
- Orally active, reversible enteropeptidase inhibitor.
- Low-nanomolar potency against rat and human enteropeptidase (reported IC50s).
- Suitable for in vitro and in vivo studies of protein digestion and metabolic pathways.
- Provided as a stable hydrochloride salt for reproducible handling.
- High purity suitable for research applications (reported purity 98.1%).
Medchemexpress LLC Emprumapimod hydrochloride (PF-07265803 hydrochloride) | 1036404-17-7 | 98.0% | C24H30ClF2N5O3 | 1 MG
Emprumapimod (PF-07265803) hydrochloride is an orally active and selective inhibitor of p38α MAPK.
- Can be used for the research of dilated cardiomyopathy.
- Can be used for the research of acute inflammatory pain.
Medchemexpress LLC 2H,5H-Benzopyrano[4,3-b]-1,4-oxazin-9-ol, 3,4,4a,10b-tetrahydro-4-propyl-, hydrochloride | 300576-59-4 | 98.9% | 285.77 | 100 MG
(+)-PD 128907 hydrochloride is a biochemical reagent used as a biological material or organic compound for life science research. It is a selective dopamine D2/D3 receptor agonist. It displaces [3H]spiperone binding from dopamine D3 receptors with high selectivity over dopamine D2 receptors. In vivo, it significantly decreases dialysate DA levels in D3 knock out mice.
- Potent and selective dopamine D3 receptor agonist
- Used as a biochemical reagent for life science research
- Shows high selectivity over dopamine D2 receptors
- Decreases dialysate DA levels in D3 knock out mice
Medchemexpress LLC CDK4/6-IN-15 (hydrochloride) | 99.0% | C21H28ClFN8S | 50 MG
CDK4/6-IN-15 hydrochloride (MedChemExpress HY-142076A) is an orally active and selective inhibitor of CDK4/6. This compound potently inhibits cancer cell growth and is intended for use as a laboratory chemical in research applications.
- Potently inhibits cancer cell growth.
- Stable under recommended storage conditions.
- Purity of 99.0% by HPLC.
- Appears as a light yellow to yellow solid.
eMolecules 6971-45-5 | (2-Methoxyphenyl)hydrazine hydrochloride | ChemScene | MFCD00035456 | 174.630 | C7H11ClN2O | 97.000 | Cl.COc1ccccc1NN | 1g | 791179964
(2-Methoxyphenyl)hydrazine hydrochloride | ChemScene | 6971-45-5 | MFCD00035456 | 174.630 | C7H11ClN2O | 97.000 | Cl.COc1ccccc1NN | 1g | 791179964
eMolecules 6971-45-5 | 2-Methoxyphenylhydrazine Hydrochloride | Ambeed | MFCD00035456 | 174.630 | C7H11ClN2O | 96.000 | Cl.COc1ccccc1NN | 25g | 552742606
2-Methoxyphenylhydrazine Hydrochloride | Ambeed | 6971-45-5 | MFCD00035456 | 174.630 | C7H11ClN2O | 96.000 | Cl.COc1ccccc1NN | 25g | 552742606
eMolecules 6971-45-5 | 2-Methoxyphenylhydrazine Hydrochloride | Ambeed | MFCD00035456 | 174.630 | C7H11ClN2O | 96.000 | Cl.COc1ccccc1NN | 1g | 552742602
2-Methoxyphenylhydrazine Hydrochloride | Ambeed | 6971-45-5 | MFCD00035456 | 174.630 | C7H11ClN2O | 96.000 | Cl.COc1ccccc1NN | 1g | 552742602
Medchemexpress LLC Pipendoxifene hydrochloride | 245124-69-0 | 99.8% | 493.04 | 50 MG
Pipendoxifene hydrochloride is a selective estrogen receptor modulator (SERM) that can be used for the research of breast cancer.
- Selective estrogen receptor modulator (SERM)
- Used for the research of breast cancer
Medchemexpress LLC M-PEG3-0-benzaldehyde | 153364-63-7 | >98% | C14H20O5 | 1 G
m-PEG3-0-benzaldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. PROTACs function by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Exploits the intracellular ubiquitin-proteasome system.
- Selectively degrades target proteins.