Styrenes
Medchemexpress LLC K858 (Racemic) | 72926-24-0 | 99.8% | 277.35 | 100 MG
K858 (Racemic) | 72926-24-0 | 99.8% | 277.35 | 100 MG
TARGETMOL CHEMICALS INC 653-47 hydrochloride 5MG
Also available in 1 mL, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. 653-47 hydrochloride is a potentiator, significantly potentiates the cAMP-response element binding protein (CREB) inhibitory activity of 666-15. It is also a very weak CREB inhibitor with IC50 of 26.3 uM. Purity 99.65%
Medchemexpress LLC CPI-637 | 1884712-47-3 | 99.9% | 386.45 | C22H22N6O | 100 MG
CPI-637 is a selective, cell-active CBP/EP300 bromodomain inhibitor that exhibits low-nanomolar biochemical potency and confirmed cellular activity. It inhibits CBP and EP300 with IC50 values in the tens of nanomolar range, shows substantially weaker activity against BRD4 BD-1, and has reported cellular EC50 and antiproliferative effects in multiple cancer cell lines. It is supplied as a high-purity research compound for epigenetics and oncology studies.
- Selective CBP/EP300 bromodomain inhibition.
- Low-nanomolar biochemical potency.
- Demonstrated cellular activity and EC50 measurements.
- Antiproliferative effects reported in multiple cancer cell lines.
- High chemical purity suitable for research.
- Supplied as a 100 mg research pack.
Medchemexpress LLC ODN INH 18 sodium | DNA, d(P-thio)(C-C-T-G-G-A-T-G-G-G-A-A-C-T-T-A-C-C-G-C-T-G-C-A）, sodium salt | 1 MG
ODN INH-18 sodium is a linear 24-mer class B INH-ODN. It shows inhibitory potency for TLR9 ligand-induced IFN-α production and is for research use only.
- Linear 24-mer class B INH-ODN
- 5' INH-ODN 4084-F sequence followed by a random stretch of 12 nucleotides
- Lacks ability to form significant secondary structures
Medchemexpress LLC Poly(styrene)-block-poly(acrylic acid) (PS:PAA 30000:2000) | 90.0% | 50 MG
Poly(styrene)-block-poly(acrylic acid) (PS:PAA 30000:2000) is a diblock copolymer utilized in the preparation of polymer micelles or vesicles and other encapsulation applications. This product is intended for research use only.
- Solid appearance
- White to off-white color
- Soluble in DMF (25 mg/mL with ultrasonic) and THF (20 mg/mL with ultrasonic)
- Ships at room temperature in continental US
- Storage as powder at -20°C for 3 years
- Storage in solvent at -80°C for 6 months, -20°C for 1 month
![Medchemexpress LLC (4R)-1,3,4,5-tetrahydro-4-methyl-6-[1-methyl-3-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-5-yl]-2H-1,5-be | 1884712-47-3 | MFCD30489741 | 99.9% | 386.45 | C22H22N6O | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000213781.png-250.jpg)
Medchemexpress LLC (4R)-1,3,4,5-tetrahydro-4-methyl-6-[1-methyl-3-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-5-yl]-2H-1,5-be | 1884712-47-3 | MFCD30489741 | 99.9% | 386.45 | C22H22N6O | 50 MG
CPI-637 is a selective, cell-active benzodiazepinone inhibitor of the CBP and EP300 bromodomains used as a research reagent for epigenetic and cancer-biology studies. It shows nanomolar biochemical potency and cellular target engagement and is supplied as a high-purity solid for laboratory use.
- Selective CBP/EP300 bromodomain inhibition (CBP IC50 ≈ 0.03 μM; EP300 IC50 ≈ 0.051 μM).
- Low activity against BRD4 BD-1 (IC50 ≈ 11.0 μM), indicating >700-fold selectivity.
- Cellular activity with CBP BRET EC50 ≈ 0.3 μM.
- High purity solid suitable for biochemical and cellular assays.
- Stable under recommended storage conditions (powder: -20°C; in solvent: -80°C).
- Available in small research package sizes (for example, 50 mg).
Sigma Aldrich Fine Chemicals Biosciences Cinnamyl alcohol >=98%, FG | 104-54-1 | MFCD00002921 |
Cinnamyl alcohol >=98%, FG | Purity: >=98% | Mol Wt: 134.18 | 104-54-1 | MFCD00002921 |
eMolecules 524684-52-4 | Medchem Express | Prinaberel | 10mg | 446264801 | HY-14933 | MFCD09954141 | 271.247 | C15H10FNO3
Medchem Express | Prinaberel | 10mg | 446264801 | HY-14933 | 524684-52-4 | MFCD09954141 | 271.247 | C15H10FNO3
Medchemexpress LLC CFTR(inh)-172 | 307510-92-5 | 99.8% | 409.40 | 1 MG
CFTR(inh)-172 is a potent and selective blocker of the CFTR chloride channel. It reversibly inhibits CFTR short-circuit current in less than 2 minutes with a Ki of 300 nM. The inhibition is complete in approximately 10 minutes (t1/2=4 minutes) and is reversed after washout with a t1/2 of approximately 5 minutes. It is nontoxic to FRT cells after 24 hours at concentrations up to 100 μM. It reduces open probability by > 90% and significantly reduces cholera toxin-induced fluid secretion in mouse models.
- Potent and selective blocker of the CFTR chloride channel.
- Reversibly inhibits CFTR short-circuit current.
- Nontoxic to FRT cells at concentrations up to 100 μM.
- Reduces open probability of CFTR by > 90%.
- Reduces cholera toxin-induced fluid secretion in mouse models.