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Styrenes

Organic compounds that consist of a benzene ring with a vinyl functional group in the following chemical formula: C₆H₅CH=CH₂; can also be called vinyl benzene.

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Medchemexpress LLC Benzamide, 2-[[5-bromo-2-[[1-(methylsulfonyl)-4-piperidinyl)amino]-4-pyrimidinyl]amino]-6-fluoro- | 2488892-01-7 | C17H20BrFN6O3S | 25 MG
SDP

TMX-2039 is a pan-CDK inhibitor for both cell cycle CDKs (CDK1, CDK2, CDK4, CDK5, and CDK6) and transcriptional CDKs (CDK7 and CDK9). It acts as a ligand for target proteins for PROTACs, demonstrating IC50 values against CDK1 (2.6 nM), CDK2 (1.0 nM), CDK4 (52.1 nM), CDK5 (0.5 nM), CDK6 (35.0 nM), CDK7 (32.5 nM), and CDK9 (25 nM).

  • Pan-CDK inhibitor
  • Inhibits cell cycle CDKs
  • Inhibits transcriptional CDKs
  • Ligand for target protein for PROTACs

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2

Medchemexpress LLC Benzonitrile, 4-[5-chloro-7-[[(1R)-1,2,2-trimethylpropyl]amino]triazolo[1,5-a]pyrimidin-6-yl]-3,5-difluoro- | 2699937-76-1 | 99.5% | 390.82 | 5 MG
SDP

Microtubule stabilizer-1 (compound 69) is a brain-penetrant microtubule (MT) stabilizer. It increases acetylated α-tubulin (AcTub) levels and prevents the characteristic loss of neuronal MTs observed after incubation with Okadaic acid. This compound can be used for the study of Alzheimer's disease (AD) and related neurodegenerative tauopathies.

  • Brain-penetrant microtubule (MT) stabilizer
  • Increases acetylated α-tubulin (AcTub) levels
  • Prevents loss of neuronal MTs after Okadaic acid incubation
  • Used for Alzheimer's disease (AD) and neurodegenerative tauopathies research

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3

Medchemexpress LLC 2-((5-bromo-2-((1-(methylsulfonyl)piperidin-4-yl)amino)pyrimidin-4-yl)amino)-6-fluorobenzamide | 2488892-01-7 | 99.4% | 487.35 g/mol | C17H20BrFN6O3S | 10 MG
SDP

TMX-2039 is a research-grade pan-cyclin-dependent kinase (pan-CDK) inhibitor intended for biochemical and cellular studies of cell cycle and transcriptional CDKs. Supplied as an off-white to light yellow solid with high reported purity, it is suitable for assay development, mechanism-of-action experiments, and probe validation in research settings.

  • Pan-CDK activity covering cell cycle and transcriptional CDKs.
  • High purity (≈99.4%) suitable for research applications.
  • Supplied as a solid powder for flexible formulation and dosing.
  • Available in small research-friendly pack sizes, e.g. 10 mg.
  • Stable under recommended storage: 4°C under nitrogen; in solvent, -80°C for 6 months or -20°C for 1 month.
  • Provides consistent material for biochemical and cellular assays.

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